Protein Alignment Cyp4s3 and Cyp26b1

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_780684.1
• Gene: Cyp26b1 / 232174
• MGIID: 2176159
• Length: 512
• Species: Mus musculus
• Alignment Length: 528
• Identity: 123/528 - (23%)
• Similarity: 216/528 - (40%)
• Gaps: 102/528 - (19%)

  Fly     1 MSTLA--LVAFVLWAAFLRYLPKILNFLRLQRFAKT--------LPGPTIG-ELIANVKKGEILN 54
            ::|||  ||:..|..|..:.|.::       |:|.|        :|..::| .||     ||..:
Mouse    12 LATLAACLVSVTLLLAVSQQLWQL-------RWAATRDKSCKLPIPKGSMGFPLI-----GETGH 64

  Fly    55 WL-------KELREKHGPVFRIWFGKDLMVMFTDPEDIKQ-LLGNNQLLTKS--RNYELLEPWLG 109
            ||       ...|||:|.||:.......::..|..|:::: |||.:||::..  |:..:|   ||
Mouse    65 WLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILLGEHQLVSTEWPRSARVL---LG 126

  Fly   110 KGLLTNG-GESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRT-KANGESFDIYPYITLF 172
            ...:.|. |:....:||:.:..|....|..:...::   .::...||. .:..|:.::|......
Mouse   127 PNTVANSIGDIHRNKRKVFSKIFSHEALESYLPKIQ---LVIQDTLRAWSSQPEAINVYQEAQRL 188

  Fly   173 ALDAICETAMG--IKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAAL 235
            .........:|  |.:.........|.|.|:::..:.....||.::|
Mouse   189 TFRMAVRVLLGFSIPEEDLGHLFEVYQQFVENVFSLPVDLPFSGYRR------------------ 235

  Fly   236 KVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREE 300
               ..:..::::...|:.|:|:.:.....:..|.        ||:|:.:..|.|.|::..::::.
Mouse   236 ---GIQARQILQKGLEKAIREKLQCTQGKDYSDA--------LDILIESSKEHGKEMTMQELKDG 289

  Fly   301 VDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEE----------ASELEGREK----ESMPYL 351
            ....:|..:.||:||....:..|.|:|.|.::..||          ....||..:    .|:.||
Mouse   290 TLELIFAAYATTASASTSLIMQLLKHPAVLEKLREELRAQGLLHGGGCPCEGTLRLDTLSSLRYL 354

  Fly   352 EAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRF-- 414
            :.||||.:|::..|....|.||:..|:....:|||.|:...|...|.....|.|...||||||
Mouse   355 DCVIKEVMRLFTPVSGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQ 419

  Fly   415 LVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQPKPLAELVTKSGN 479
            ..:|.:...|.:..|..|.|.|:|:..|.|.||.....|..:.||            ||.|::..
Mouse   420 ARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRF------------ELATRTFP 472

  Fly   480 GIRLRILP 487
              |:.::|
Mouse   473 --RITLVP 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	99/441 (22%)
Cyp26b1	NP_780684.1	CYP26B1	60..490	CDD:410730	108/468 (23%)