Protein Alignment Cyp4s3 and cyp-13A7

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_496114.1
• Gene: cyp-13A7 / 188362
• WormBaseID: WBGene00000372
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 134/510 - (26%)
• Similarity: 232/510 - (45%)
• Gaps: 74/510 - (14%)

  Fly     1 MSTLALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPG-PTIGEL--IANVKKGEILNWLKELREK 62
            ||...|:|..::...:.|...|.:|. :::..|...| |.:|.:  ..|.:....|.: .|..:|
 Worm     1 MSFSILIAIAIFVGIISYYLWIWSFW-IRKGVKGPRGLPFLGVIHKFTNYENPGALKF-SEWTKK 63

  Fly    63 HGPVFRIWFGKDLMVMFTDPEDIKQLLGN------NQLLTKSRNYELLEPWLGK--GLLTNGGES 119
            :|||:.|..|.:..::.:|||.:.::...      .:.||..:.    :|...|  .|:...|..
 Worm    64 YGPVYGITEGVEKTLVISDPEFVHEVFVKQFDNFYGRKLTAIQG----DPNKNKRVPLVAAQGHR 124

  Fly   120 WHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRL-RTKANGESFDIYPYITLFALDAICETAMG 183
            |.|.|.|.:|.|..:.|.:....:||:...|||.| :..|.|::.|:..|...|.:|.|.:.|||
 Worm   125 WKRLRTLASPTFSNKSLRKIMGTVEESVTELVRSLEKASAEGKTLDMLEYYQEFTMDIIGKMAMG 189

  Fly   184 IKKHAQLQSDSEYVQAVQSICR------VMHKQSFSF--WQRLNVFFKHTKPGKEREAALK-VLH 239
            .:|  .|...:..:..|::|.:      .|....|.|  ....|:|.|.  |..:....:: :|.
 Worm   190 QEK--SLMFRNPMLDKVKTIFKEGRNNVFMISGIFPFVGIALRNIFAKF--PSLQMATDIQSILE 250

  Fly   240 DETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLL-----LTQMEGGAE-------- 291
            ...|:  ||.:.: ..|:...:|..|..|        |:|:.|     :...||.||
 Worm   251 KALNK--RLEQRE-ADEKAGIEPSGEPQD--------FIDLFLDARSTVDFFEGEAEQDFAKSEV 304

  Fly   292 ------LSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEAS------ELEGRE 344
                  |:..:|..::..|:..|:|||:.:::::..||:.:|::|::..||..      |:...:
 Worm   305 LKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVDRECPDPEVTFDQ 369

  Fly   345 KESMPYLEAVIKETLRIYPSVPF-FSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNF-PDPE 407
            ...:.|||.|:||.||:||.... .:||.|:...|..:.:..|.:|:...:.||.|||.: .|..
 Worm   370 LSKLKYLECVVKEALRLYPLASLVHNRKCLKTTNVLGMEIEAGTNINVDTWSLHHDPKVWGDDVN 434

  Fly   408 RFDPDRFLVNEKQMHPFA---FAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF 459
            .|.|:|:...::..  ||   :..|..|||.|||.:.||:|:|..|..:|::|.|
 Worm   435 EFKPERWESGDELF--FAKGGYLPFGMGPRICIGMRLAMMEMKMLLTNILKNYTF 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	119/444 (27%)
cyp-13A7	NP_496114.1	CYP3A-like	63..507	CDD:410678	120/446 (27%)