Protein Alignment Cyp4s3 and cyp-13A1

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001369869.1
• Gene: cyp-13A1 / 188361
• WormBaseID: WBGene00011677
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 121/547 - (22%)
• Similarity: 222/547 - (40%)
• Gaps: 102/547 - (18%)

  Fly     4 LALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGPTIGELIANVKKG-----EILNWLKELREKH 63
            :|:.::.:|.         ..|.|.:.....:..|.:|..:.::...     :...|.|    |.
 Worm    14 VAVFSYYIWQ---------WTFWRRRGVVGPMGFPVLGVFLNSLDNNFPFPLQCREWTK----KF 65

  Fly    64 GPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNY--ELLEPWLG-------KGLLTNGGES 119
            |.::....|....::.:|||.:.::     .:|:..|:  ....|..|       ..|....|..
 Worm    66 GKIYGFTEGTLKTLVISDPELVHEV-----FVTQYDNFYGRKRNPIQGDSEKEKRTNLFAAQGFR 125

  Fly   120 WHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRL-RTKANGESFDIYPYITLFALDAICETAMG 183
            |.|.|.:.:|.|....|.:..:.:|::...|:|.: :..|.|:..|:..:...|.||.|...|||
 Worm   126 WKRLRAISSPTFSNSSLRKLYQTVEDSALELLRHIEKQSAGGKQIDMLKFYQEFTLDVIGRIAMG 190

  Fly   184 IKKHAQLQSDSE-YVQAVQSICRVMHKQSF-----------SFWQRL--NVFFKHTKPG---KER 231
                   |:||: :...:..|...:.:.:|           :|...:  .:..|:.|.|   |..
 Worm   191 -------QTDSQMFKNPIMPIVSKLFQGNFAKLFLIGGIFPTFLVEIIRQILLKNLKVGSFRKIN 248

  Fly   232 EAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEG-------- 288
            |..|..:|   ||:             :.:.|.:::.:.......|:|:.|..:.|.
 Worm   249 EITLDAIH---NRI-------------KQREEDQKNGIEIGEPADFIDLFLDAKAEDVEHFGENN 297

  Fly   289 ----------GAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEAS----- 338
                      ..:|:..:|..:...|:..|.|||:.::::|..||:.:|::|::..||.:
 Worm   298 GDFSKSTTYTNRQLTTEEIVGQCTVFLIAGFDTTALSLSYATYLLATHPEIQKKLQEEVNRECPN 362

  Fly   339 -ELEGREKESMPYLEAVIKETLRIYPSVPFF-SRKVLEDLEVGKLTVPKGASISCLIYMLHRDPK 401
             |:...:...:.|:|.|.||.||:||...|. ||:.:.:.::|.:.|..|..|....:.||.||.
 Worm   363 PEVTIDQLSKLKYMECVFKEALRLYPLGAFANSRRCMRNTKLGNMKVEVGTMIQVDTWTLHTDPN 427

  Fly   402 NF-PDPERFDPDRFLV-NEKQMH-PFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF-LPD 462
            .: .|.|.|.|:|:.. |..|:: ...:..|..|||.|||.:.|.:|.|..|..:||.:.| ...
 Worm   428 IWGDDAEDFKPERWQTPNSDQIYQKSGYIPFGLGPRQCIGMRLAYMEEKILLVHILRKFTFETGA 492

  Fly   463 KDHQPKPLAELVTKSGNGIRLRILPRD 489
            |...|..|....|.....:.:.:.||:
 Worm   493 KTEIPLKLIGRATTQPESVWMHLNPRN 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	110/474 (23%)
cyp-13A1	NP_001369869.1	CYP3A-like	64..510	CDD:410678	111/473 (23%)