Protein Alignment Cyp4s3 and cyp-13A3

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_496110.1
• Gene: cyp-13A3 / 188359
• WormBaseID: WBGene00011675
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 556
• Identity: 133/556 - (23%)
• Similarity: 236/556 - (42%)
• Gaps: 107/556 - (19%)

  Fly     1 MSTLALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGPT------IGELIANVKKGEIL---NWL 56
            ||...|:|..|:.....|...|.:|.    ..|.:.||.      |.....:.:|..||   :|.
 Worm     1 MSLSILIAIALFIGVFTYYLWIWSFW----MRKGIKGPRGLPFFGIINAFQSYEKPWILRLGDWT 61

  Fly    57 KELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGN--NQLLTKSRNYELLEPWLGK-------GL 112
            ||    :||::....|.:..::.:|||.:.::...  :....:.:|     |..|.       .|
 Worm    62 KE----YGPMYGFTDGVEKTLVVSDPEFVHEVFVKQFDNFYARKQN-----PLQGDPDKDPRIHL 117

  Fly   113 LTNGGESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRL-RTKANGESFDIYPYITLFALDA 176
            :|:.|..|.|.|.|.:|.|..:.|.:....:||:...::|.| :..|.|::.||..|...|.:|.
 Worm   118 VTSQGHRWKRLRTLASPTFSNKSLRKIFSTVEESVAEMMRHLEKGTAGGKTIDILEYYQEFTMDI 182

  Fly   177 ICETAMGIKKHAQLQSDSEYVQAVQS-----------ICRVMHKQSFSF-WQRLNVFFKHTKPGK 229
            |.:.|||  :...:..::.::..:::           ||.::......| |     ||......:
 Worm   183 IGKIAMG--QSGSMMFENPWLDKIRAIFNTRGNIIFIICGIVPFTGSIFRW-----FFSKVPTAQ 240

  Fly   230 EREAALKVLHDE-TNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELS 293
            ...:.:..|... |.||    .::...|:...:...|..|        |:|:.|..|       :
 Worm   241 TVTSLMHTLEIALTKRV----EQRAADEKAGIESSGEPQD--------FIDLFLDVQ-------A 286

  Fly   294 DTDIREE-------------VD-------------TFMFEGHDTTSSAIAFALSLLSKNPDVQQR 332
            |||..|:             ||             .|:..|:|||:.:::::..||:::|::|::
 Worm   287 DTDFLEDETKNGFARSQIVKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKK 351

  Fly   333 AFEEAS------ELEGREKESMPYLEAVIKETLRIYPSVPF-FSRKVLEDLEVGKLTVPKGASIS 390
            ..||..      |:...:...:.|:|.|||||||:||.... .:||.::...|..:.:.:|.::.
 Worm   352 LQEEVDRECPDPEVTFDQLSKLKYMECVIKETLRLYPLASIVHNRKCMKSTTVLGMKIEEGTNVQ 416

  Fly   391 CLIYMLHRDPKNF-PDPERFDPDRFLVNEKQ-MHPFAFAAFSAGPRNCIGQKFAMLELKTSLAML 453
            ...:.||.|||.: .:...|.|:|:...::| :...|:..|..|||.|||.:.|.:|.|..||.:
 Worm   417 ADTWTLHYDPKFWGENANEFKPERWESGDEQAVAKGAYLPFGLGPRICIGMRLAYMEEKMLLAQI 481

  Fly   454 LRSYRF-LPDKDHQPKPLAELVTKSGNGIRLRILPR 488
            |:.|.. ...:.|.|..|..:.|.:...:.|::.||
 Worm   482 LKKYSLETTFETHIPLKLVGIATTAPTNVHLKLKPR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	112/477 (23%)
cyp-13A3	NP_496110.1	CYP3A-like	63..509	CDD:410678	113/480 (24%)