Protein Alignment Cyp4s3 and cyp-13A6

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_496113.1
• Gene: cyp-13A6 / 188357
• WormBaseID: WBGene00011673
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 570
• Identity: 130/570 - (22%)
• Similarity: 223/570 - (39%)
• Gaps: 139/570 - (24%)

  Fly     1 MSTLALVAFV----LWAAFLRYLPKILNFLRLQRFAKTLPGPT----IGELIANVKKG-----EI 52
            :|.:.|..|.    :|:.|:|               |.:.||.    ||.||..:...     :.
 Worm     6 LSAVLLGVFTYSVWIWSYFIR---------------KGIKGPRGFPGIGMLIQTIDHENPPFLKY 55

  Fly    53 LNWLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKS-RNY--ELLEPWLGK---- 110
            .:|.|:    :|||:....|....::.::||.:      |::..|. .|:  ..|.|.:|.
 Worm    56 RDWTKQ----YGPVYGFTEGPQQTMIISEPEMV------NEIFKKQFDNFYGRKLRPIIGDPEKD 110

  Fly   111 ---GLLTNGGESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKA-NGESFDIYPYITL 171
               .:.:..|:.|.|.|.|.:|.|....|.:.:..::|....::..:..|. ..|..|:......
 Worm   111 KRVNIFSTQGKRWKRLRTLSSPSFSNNSLRKVRNSVQECGTEILWNIEQKVRKNEDIDMLIVYQE 175

  Fly   172 FALDAICETAMGIKKHAQLQSDSEY--------VQAV-----------------QSICRVMHKQ- 210
            :.|..|...|:|       ||:|..        |||:                 ..:.|.|.|.
 Worm   176 YTLGVISRIALG-------QSESNMFKNPLLPKVQAIFNGSWHVFLITGIFPPLAGVFRKMSKML 233

  Fly   211 SFSFWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRL 275
            ..||.....:|                  |.....::.|.:|..::..:.....|..|
 Worm   234 PASFIPAFKIF------------------DLIEVAVQARIDQRAKDEIKGVEPGEPQD------- 273

  Fly   276 AFLDMLL------LTQMEGGA--------------ELSDTDIREEVDTFMFEGHDTTSSAIAFAL 320
             |:|:.|      :..:.|.|              ||:..:|..:...|:..|.|||:.::::|.
 Worm   274 -FIDLFLDARVPDVKILSGEANEDFAKSSVVKINKELTFDEIIAQCFVFLAAGFDTTALSLSYAT 337

  Fly   321 SLLSKNPDVQQRAFEEAS------ELEGREKESMPYLEAVIKETLRIYP-SVPFFSRKVLEDLEV 378
            .||:.:|::|.:..||..      |:.......:.|||.|:|||||:|| .....:||.:.:..:
 Worm   338 YLLATHPEIQTKLQEEVDRECPDPEIFFDHLSKLKYLECVMKETLRLYPLGTTANTRKCMRETTI 402

  Fly   379 GKLTVPKGASISCLIYMLHRDPKNF-PDPERFDPDRFL--VNEKQMHPFAFAAFSAGPRNCIGQK 440
            ..:...:|.:|....:.||.:|:.: .|.|.|.|:|:.  ..|...|..::..|.:|||.|||.:
 Worm   403 NGVNFDEGMNIQVDTWTLHHNPRIWGEDVEDFKPERWENGACEHLEHNGSYIPFGSGPRQCIGMR 467

  Fly   441 FAMLELKTSLAMLLRSYRFLPDKDHQ-PKPLAELVTKSGNGIRLRILPRD 489
            .|.:|.|..||.:|:.|.|...|:.| |..|...:|.|...:.:::.|||
 Worm   468 LAQMEQKILLAQILKEYSFRTTKNTQIPVKLVGKLTLSPESVIVKLEPRD 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	112/486 (23%)
cyp-13A6	NP_496113.1	CYP3A-like	61..511	CDD:410678	112/492 (23%)