Protein Alignment Cyp4s3 and cyp-13A5

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 133/552 - (24%)
• Similarity: 229/552 - (41%)
• Gaps: 93/552 - (16%)

  Fly     1 MSTLALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGP-------TIGEL--IAN---VKKGEIL 53
            ||...|:|...:...|.|...|.:|.    ..|.:.||       .|.|.  ..|   :|.||
 Worm     1 MSLSILIAGASFIGLLTYYIWIWSFW----IRKGVKGPRGFPFFGVIHEFQDYENPGLLKLGE-- 59

  Fly    54 NWLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGN--NQLLTKSRNYELLEPWLGK--GLLT 114
             |.||    :||::.|..|.:..::.::||.:.::...  :....:..|....:|...|  .|::
 Worm    60 -WTKE----YGPIYGITEGVEKTLIVSNPEFVHEVFVKQFDNFYGRKTNPIQGDPNKNKRAHLVS 119

  Fly   115 NGGESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRL-RTKANGESFDIYPYITLFALDAIC 178
            ..|..|.|.|.|.:|.|..:.|.:....:||....|:|.| ...|.|::.|:..|...|.||.|.
 Worm   120 AQGHRWKRLRTLSSPTFSNKNLRKIMSTVEETVVELMRHLDDASAKGKAVDLLDYYQEFTLDIIG 184

  Fly   179 ETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSF--------------SFWQRLNVFFKHTKPGK 229
            ..|||  :...|...:..:..|:.|.:...|..|              .|:.|    |...:|..
 Worm   185 RIAMG--QTESLMFRNPMLPKVKGIFKDGRKLPFLVSGIFPIAGTMFREFFMR----FPSIQPAF 243

  Fly   230 EREAALKVLHDETNRVIRLRREQ-LIQERNEWKPEAEQDDVGAKRRLAFLDMLL-------LTQM 286
            :       :.....:.:..|.|| ...|:...:|..|..|        |:|:.|       ..:.
 Worm   244 D-------IMSTVEKALNKRLEQRAADEKAGIEPSGEPQD--------FIDLFLDARANVDFFEE 293

  Fly   287 EGGAELSDTDIRE------------EVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEAS- 338
            |.....:.|:|.:            ::..|:..|:|||:.:::::..||:::|::|::..||..
 Worm   294 ESALGFAKTEIAKVDKQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDR 358

  Fly   339 -----ELEGREKESMPYLEAVIKETLRIYPSVPF-FSRKVLEDLEVGKLTVPKGASISCLIYMLH 397
                 |:...:...:.|:|.|:||.||:||.... .:||.:::..|..:.:.||.::....:.||
 Worm   359 ECPNPEVTFDQISKLKYMECVVKEALRMYPLASIVHNRKCMKETNVLGVQIEKGTNVQVDTWTLH 423

  Fly   398 RDPKNF-PDPERFDPDRFLVNEKQMH-PFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFL 460
            .|||.: .|...|.|:|:...::..: ...:..|..|||.|||.:.||:|.|..|..:|:.|.|.
 Worm   424 YDPKVWGEDANEFRPERWESGDELFYAKGGYLPFGMGPRICIGMRLAMMEKKMLLTHILKKYTFE 488

  Fly   461 PDKDHQ-PKPLAELVTKSGNGIRLRILPRDEN 491
            .....: |..|....|.:...:.|::.||..|
 Worm   489 TSTQTEIPLKLVGSATTAPRSVMLKLTPRHSN 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	109/467 (23%)
cyp-13A5	NP_496112.1	CYP3A-like	63..511	CDD:410678	110/472 (23%)