Protein Alignment Cyp4s3 and CYP11B2

DIOPT Version :9

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_000489.3
• Gene: CYP11B2 / 1585
• HGNCID: 2592
• Length: 503
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 113/455 - (24%)
• Similarity: 182/455 - (40%)
• Gaps: 84/455 - (18%)

  Fly    55 WLKELR------------EKH------GPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNY 101
            ||:.|:            |.|      ||:||...|...||....|||:::|   .|:.:.....
Human    49 WLRLLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKL---QQVDSLHPCR 110

  Fly   102 ELLEPWLGK--------GLLTNGGESWHRRR-----KLLTPGFHFRILSEFKEPMEENCRILVRR 153
            .:||||:..        |:....|..|...|     .:|:|....|.|........:..:.|.::
Human   111 MILEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKK 175

  Fly   154 LRTKANGE-SFDIYPYITLFALD----AICETAMGIKKHAQLQSDSEYVQAVQSICRVMHK---- 209
            :...|.|. :.|:.|.|..:.::    |:....:|:..|:...:...::.|::    ||.|
Human   176 VLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALE----VMFKSTVQ 236

  Fly   210 -----QSFSFWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDV 269
                 :|.|.|....|:       ||...|...:....:..|    :::.||....:|:.....|
Human   237 LMFMPRSLSRWISPKVW-------KEHFEAWDCIFQYGDNCI----QKIYQELAFNRPQHYTGIV 290

  Fly   270 GAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAF 334
            .        ::||      .||||...|:...........|||:..:...|..|::||||||...
Human   291 A--------ELLL------KAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILR 341

  Fly   335 EEA-------SELEGREKESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCL 392
            :|:       ||...:....:|.|.|.:|||||:||...|..|.|..||.:....:|.|..:...
Human   342 QESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVF 406

  Fly   393 IYMLHRDPKNFPDPERFDPDRFLVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSY 457
            :|.|.|:...||.|||::|.|:|........|....|..|.|.|:|::.|..|:...|..:|:.:
Human   407 LYSLGRNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHF 471

  Fly   458  457
            Human   472  471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	113/455 (25%)
CYP11B2	NP_000489.3	p450	42..454	CDD:365848	109/436 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910