DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4s3 and cyp-31A5

DIOPT Version :9

Sequence 1:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001343697.1	Gene:	cyp-31A5 / 13198891	WormBaseID:	WBGene00013381	Length:	308	Species:	Caenorhabditis elegans

Alignment Length:	219	Identity:	76/219 - (34%)
Similarity:	116/219 - (52%)	Gaps:	16/219 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 IWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGKGLLTNGGESWHRRRKLLTPGFHF 133
            :|.|....:|....:.::.:..:.:.|.|...|.|||||||..:||:..|.|..:||||||.||:
Worm    74 LWIGPFPCLMLYSADLVEPIFSSTKHLNKGFAYVLLEPWLGISILTSQKEQWRPKRKLLTPTFHY 138

  Fly   134 RILSEFKEPMEENCRILVRRL-RTKANGESFDIYPYITLFALDAICETAMGIKKHAQLQSDSEYV 197
            .||.:|.....|..:||:::| ......|..|:...|||..||.||||:||....|||..::|||
Worm   139 DILKDFLPIFNEQSKILIQKLCCLGVADEEVDVLSVITLCTLDIICETSMGKAIGAQLAENNEYV 203

  Fly   198 QAVQSICRVMHKQSFS--FWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQLIQERNEW 260
            .||.:|.:::.|::.:  .|.  :..:..|:.|:..|..|.:|||.|.:||..|:|.|  :.:::
Worm   204 WAVHTINKLISKRTNNPLMWN--SFIYNLTEDGRTHEKCLHILHDFTKKVIVERKEAL--QDSDY 264

  Fly   261 KPEAEQDDVGAKRRLAFLDMLLLT 284
            |.|.         ||||...:..|
Worm   265 KMEG---------RLAFSRQICCT 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	76/219 (35%)
cyp-31A5	NP_001343697.1	p450	36..>261	CDD:325183	69/190 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820