Protein Alignment Cyp4s3 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 521
• Identity: 206/521 - (39%)
• Similarity: 301/521 - (57%)
• Gaps: 50/521 - (9%)

  Fly    10 VLWAA-----------FLRYLPKILNFLRLQRFAKTLPG-----PTIGELIANVKKG-----EIL 53
            :||.|           .:...|.::::.|..:..:::|.     |.:|..:......     :::
Mouse    14 LLWGAASAVSLAGATILISIFPMLVSYARKWQQMRSIPSVARAYPLVGHALYMKPNNAEFFQQLI 78

  Fly    54 NWLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGKGLLTNGGE 118
            .:.:|.|  |.|:.::|.|...:|.....|:::.:|.:::.:.||..|:.|:||||.||||:.|.
Mouse    79 YYTEEFR--HLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFLYKFLQPWLGLGLLTSTGS 141

  Fly   119 SWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICETAMG 183
            .|..|||:|||.|||.||..|.:.|.|...|||.:|....|.|:|:.:.||||.|||.|||||||
Mouse   142 KWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEKHVNQEAFNCFFYITLCALDIICETAMG 206

  Fly   184 IKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRL 248
            ....||..:|||||:.|..:..:::::....|...::::...|.|::.:..||.||..||.||..
Mouse   207 KNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKRGLKCLHTFTNNVIAE 271

  Fly   249 RREQLIQERNEWKPEAEQDDVGAKR--------RLAFLDMLLLTQMEGGAELSDTDIREEVDTFM 305
            |    ::||     :||:|..||.|        |.||||:||....|.|..||..||||||||||
Mouse   272 R----VKER-----KAEEDWTGAGRGPIPSKNKRKAFLDLLLSVTDEEGNRLSQEDIREEVDTFM 327

  Fly   306 FEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGR--------EKESMPYLEAVIKETLRIY 362
            |||||||::||.::|.||..||:||::..:|..|:.||        :.:.:.||:.|||||||::
Mouse   328 FEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSHRPVTLEDLKKLKYLDCVIKETLRVF 392

  Fly   363 PSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFL-VNEKQMHPFAF 426
            ||||.|:|.:.||.|||...|.||.....:.|.|||||:.|||||.|.|:||. .|.:..||:|:
Mouse   393 PSVPLFARSLSEDCEVGGYKVTKGTEAIIIPYALHRDPRYFPDPEEFRPERFFPENSQGRHPYAY 457

  Fly   427 AAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQPKPLA-ELVTKSGNGIRLRILPRDE 490
            ..||||||||||||||::|.||.||.:||.:....::..:...|| :|:.:..|||.:::..|.|
Mouse   458 VPFSAGPRNCIGQKFAVMEEKTILACILRQFWVESNQKREELGLAGDLILRPNNGIWIKLKRRHE 522

  Fly   491 N 491
            :
Mouse   523 D 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	193/436 (44%)
Cyp4v3	NP_598730.1	CYP4V	76..515	CDD:410773	196/449 (44%)