Protein Alignment Cyp4s3 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 527
• Identity: 138/527 - (26%)
• Similarity: 240/527 - (45%)
• Gaps: 98/527 - (18%)

  Fly     5 ALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGP-----TIGELIANVKKGE---------ILNW 55
            |:|||:.:.|:::|:.  |.:       ..:|||     .:|. |..:.|.|         .|:|
 Frog    24 AVVAFLAYCAYIKYMH--LKY-------DDIPGPPRDSFLLGH-IPTLSKAEENYSVVHDLFLHW 78

  Fly    56 LKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELL-----EPWLGKGLLTN 115
                .|.:||||:|.....:|:..|.||.:|:.|.:::.......|..|     :.:|||||||:
 Frog    79 ----AEIYGPVFKINILHRVMIYSTSPESVKECLMSSKYPKDPYTYNQLFNLFGKRFLGKGLLTD 139

  Fly   116 -GGESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKANG-ESFDIYPYITLFALDAIC 178
             ..:.|:.:|:::.|.|....|.|......|....::.:|..||:| :...::..|....||.|.
 Frog   140 PDHDHWYHQRRIMDPAFSNTYLKEMIGIFNERAEQMMEKLEEKADGHQEVSMHSIINRVTLDVIT 204

  Fly   179 ETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQR--LNVFFKHTKPGKEREAALKVLHDE 241
            :.|.|:.......:.:::..|:..:...|.:    :.|.  :..|.||....:|.:        |
 Frog   205 KVAFGMDLGLVEGNKTDFPNAISKVLTGMMR----YMQNPYMQYFPKHWAFVREVQ--------E 257

  Fly   242 TNRVIRLRREQLIQERNEWKPEAEQ--DDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTF 304
            :..::|...::.|.:|.:.....|:  .|:..|       :|...::|..  |.|..:.:...||
 Frog   258 SADLLRKTGKECISQRKKAMQNGEELPKDILTK-------ILQCAELENA--LDDEIMLDNFITF 313

  Fly   305 MFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGREK-------ESMPYLEAVIKETLRIY 362
            ...|.:||::.::|.:..|::.|::..:...|..|:.|.::       :::.|:..|:||:||.|
 Frog   314 FIAGQETTANQLSFTVMELTRQPEIMTKLRMEVDEVIGFKRDISYDDIQNLNYMTQVLKESLRFY 378

  Fly   363 PSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFLVNEKQMHP---- 423
            |..|..||.:.||.....:.:|.|.||:...|::.|..|.|.||.:|||:||       ||
 Frog   379 PPGPGTSRYLKEDTIFEGIKIPGGVSITFNTYVMGRMEKFFQDPCKFDPERF-------HPAAVK 436

  Fly   424 --FAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQPKPLAELVTKSGNGIR---- 482
              |.:..|:.|||:|:||.|:.||.|..|:.|::.:.|            |||.....||:
 Frog   437 PYFCYFPFALGPRSCLGQIFSQLEAKVILSKLIQRFEF------------ELVPGQSFGIKDTGT 489

  Fly   483 LRILPRD 489
            ||  |||
 Frog   490 LR--PRD 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	116/446 (26%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	124/469 (26%)