Protein Alignment Cyp4s3 and cyp19a1

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001090630.1
• Gene: cyp19a1 / 100036594
• XenbaseID: XB-GENE-953895
• Length: 500
• Species: Xenopus tropicalis
• Alignment Length: 495
• Identity: 115/495 - (23%)
• Similarity: 202/495 - (40%)
• Gaps: 97/495 - (19%)

  Fly     2 STLALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGPT----IGELIANVK-----KGEILNWLK 57
            :|::|:.|:.          :|..|..|.....:|||.    :|.||:..:     .|:..|:..
 Frog    22 TTVSLLLFIF----------LLIILWNQEETCLIPGPAYCMGLGPLISYGRFLLTGIGKAANYYN 76

  Fly    58 ELREKHGPVFRIWF-GKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLG--------KGLL 113
            .:   :|...|:|. |::.:|       |.:......::..|.........||        .|::
 Frog    77 NM---YGEFVRVWINGEETLV-------ISKASATFHIMKHSHYISRFGSKLGLQCIGMNENGII 131

  Fly   114 TNGGES-WHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLR---------TKANGESFDIYPY 168
            .|...| |    |::.| |..:.||  ...:.:...|.:|..:         |...| :.|:...
 Frog   132 FNSNPSLW----KVIRP-FFIKALS--GPGLMQTTEICIRSTKRYLDNLGNVTNELG-NVDVLKL 188

  Fly   169 ITLFALDAICETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRL----NVFFKHTKPGK 229
            :.|..||    |:..:.....| .::|.|..:|        :.|..||.|    ::|||.:...|
 Frog   189 MRLIMLD----TSNNLFLRIPL-DENEIVLKIQ--------KYFDAWQALLLKPDIFFKISWLYK 240

  Fly   230 EREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSD 294
            :.|.:...|.:....:|..:|::|        ..:|:.|    ..:.|...|:..|..|  :|:.
 Frog   241 KYEKSANDLKEAIEILIEQKRQKL--------SSSEKLD----ENMDFASELIFAQNHG--DLTA 291

  Fly   295 TDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEG-REKES-----MPYLEA 353
            .::.:.:...:....||.|.::.|.|.|::::|.:::....|...:.| |:.||     :..||.
 Frog   292 ENVNQCILEMLIAAPDTMSVSLFFMLVLVAQHPKIEEGIMNEIDNVIGDRDVESNDIPNLKVLEN 356

  Fly   354 VIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFLVNE 418
            .|.|::|..|.|....||.|||..:....|.||.:|...:..:|| .:.||.|..|..:.|   |
 Frog   357 FIYESMRYQPVVDLVMRKALEDDMIDGYYVKKGTNIILNLGRMHR-IEYFPKPNEFTLENF---E 417

  Fly   419 KQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYR 458
            |.:....|..|.:|||.|.|:..||:.:|..|..|.:.|:
 Frog   418 KTVPYRYFQPFGSGPRACAGKYIAMVMMKVILVTLFKRYK 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	101/424 (24%)
cyp19a1	NP_001090630.1	CYP19A1	70..483	CDD:410709	102/437 (23%)