DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5599 and BCE2

DIOPT Version :9

Sequence 1:	NP_573000.1	Gene:	CG5599 / 32441	FlyBaseID:	FBgn0030612	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_187341.1	Gene:	BCE2 / 819869	AraportID:	AT3G06850	Length:	483	Species:	Arabidopsis thaliana

Alignment Length:	464	Identity:	181/464 - (39%)
Similarity:	256/464 - (55%)	Gaps:	51/464 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GATCWLLRNCISQRAALRRCLHVTSSLDKTVSFNLSDIGEGIREVTVKEWFVKEGDTVEQFDNLC 73
            |:..|.....::           |.|....:...|:..||||.|..:.:|||||||:||:|..||
plant    57 GSRSWFSNEAMA-----------TDSNSGLIDVPLAQTGEGIAECELLKWFVKEGDSVEEFQPLC 110

  Fly    74 EVQSDKASVTITSRYDGKITKIHHKIDEIALVGKPLLDFDVVNEDEDEPEDSSSSSSSTSSDSSA 138
            |||||||::.||||:.||:..|.|...:|..||:.|:...|        |||..|..:|.|....
plant   111 EVQSDKATIEITSRFKGKVALISHSPGDIIKVGETLVRLAV--------EDSQDSLLTTDSSEIV 167

  Fly   139 SENEEKQSAEASATPTEGRVIIPATPSVRRLAKEHQLDLAKVPATGKNGRVLKGDILEFLGQ--- 200
            :....||.       ||..:...:||:||.|||:..:|:..:..|||:|||||.|:|.|..|
plant   168 TLGGSKQG-------TENLLGALSTPAVRNLAKDLGIDINVITGTGKDGRVLKEDVLRFSDQKGF 225

  Fly   201 VPPGTNVPHPTLLAKTPSAAPSGAASVSVPA-----DRVEVLKGVRKAMLKSMTESLKIPHFAYS 260
            |....:..|..:          |..|||..|     |:...|:|..:||:|:||.:..:|||.:.
plant   226 VTDSVSSEHAVI----------GGDSVSTKASSNFEDKTVPLRGFSRAMVKTMTMATSVPHFHFV 280

  Fly   261 DEIDMTQLMQFRNQLQLVAKENGVP---KLTFMPFCIKAASIALSKYPIVNSSLDLASESLVFKG 322
            :||:...|:    :|:...|||...   |.||:|..||:.|:||:|||.|||..:..|..::.||
plant   281 EEINCDSLV----ELKQFFKENNTDSTIKHTFLPTLIKSLSMALTKYPFVNSCFNAESLEIILKG 341

  Fly   323 AHNISVAIDTPQGLVVPNIKNCQTKTIIEIAKDLNALVERGRTGSLSPADFADGTFSLSNIGVIG 387
            :|||.||:.|..|||||||||.|:.:::||.|:|:.|........|:|.|...||.:|||||.||
plant   342 SHNIGVAMATEHGLVVPNIKNVQSLSLLEITKELSRLQHLAANNKLNPEDVTGGTITLSNIGAIG 406

  Fly   388 GTYTHPCIMAPQVAIGAMGRTKAVPRFNDKDEVVKAYVMSVSWSADHRVIDGVTMASFSNVWKQY 452
            |.:..|.:..|:|||.|:||.:.||:|:.:..|..|.:|.|:.:|||||:||.|:|.|...||:|
plant   407 GKFGSPLLNLPEVAIIALGRIEKVPKFSKEGTVYPASIMMVNIAADHRVLDGATVARFCCQWKEY 471

  Fly   453 LENPALFLL 461
            :|.|.|.:|
plant   472 VEKPELLML 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5599	NP_573000.1	lipoyl_domain	39..109	CDD:133458	36/69 (52%)
		PLN02528	41..462	CDD:215289	177/432 (41%)
		E3_binding	161..194	CDD:280908	16/32 (50%)
		2-oxoacid_dh	248..461	CDD:278621	95/215 (44%)
BCE2	NP_187341.1	PLN02528	78..483	CDD:215289	177/432 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	191	1.000	Domainoid score	I943
eggNOG	1	0.900	-	-		E1_COG0508
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1444
Inparanoid	1	1.050	297	1.000	Inparanoid score	I805
OMA	1	1.010	-	-		QHG61710
OrthoDB	1	1.010	-	-		D854035at2759
OrthoFinder	1	1.000	-	-		FOG0005815
OrthoInspector	1	1.000	-	-		oto3062
orthoMCL	1	0.900	-	-		OOG6_101891
Panther	1	1.100	-	-	LDO	PTHR43178
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4793
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840