Protein Alignment CG5599 and dbt

DIOPT Version :9

• Sequence 1: NP_573000.1
• Gene: CG5599 / 32441
• FlyBaseID: FBgn0030612
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_001013533.1
• Gene: dbt / 541388
• ZFINID: ZDB-GENE-050320-85
• Length: 493
• Species: Danio rerio
• Alignment Length: 494
• Identity: 237/494 - (47%)
• Similarity: 317/494 - (64%)
• Gaps: 55/494 - (11%)

  Fly     6 LRNGATCWLLRNCISQRAA----LR------------RCLHVT-SSLDKTVSFNLSDIGEGIREV 53
            :|...:..|.|||.|:..|    ||            |..|.: .:....|.|.||||||||.||
Zfish    14 MRRLVSARLHRNCCSKLPAACLVLRPHSYSLVAGRQHRYFHTSYVAARPIVQFKLSDIGEGIMEV 78

  Fly    54 TVKEWFVKEGDTVEQFDNLCEVQSDKASVTITSRYDGKITKIHHKIDEIALVGKPLLDFDVVNED 118
            |||||:|||||.|.|||::||||||||||||||||||.|.|:::.:|.||||||||:|.:.....
Zfish    79 TVKEWYVKEGDKVSQFDSICEVQSDKASVTITSRYDGVIRKLYYDVDSIALVGKPLVDIETDGGQ 143

  Fly   119 EDEPEDSSSSSSSTSSDSSASENEEKQSAEASATPTEGRVIIPATPSVRRLAKEHQLDLAKVPAT 183
            .:.|::....:.:.|       .||....|.....|:      |||:|||||.|:.:.|::|..|
Zfish   144 AESPQEDVVETPAVS-------QEEHSPQEIKGHKTQ------ATPAVRRLAMENNIKLSEVVGT 195

  Fly   184 GKNGRVLKGDILEFLGQ-----VPPGTNVPHPTLLAKTPSAA----PSGAA---SVSVPA----- 231
            ||:||:||.|||.|:.:     :||   .|...:..:.|:||    ||..|   ||.:|.
Zfish   196 GKDGRILKEDILNFIAKQTGAILPP---APFQEIRPQPPAAAAPLTPSAKATPPSVPIPVIPKPV 257

  Fly   232 ----DRVEVLKGVRKAMLKSMTESLKIPHFAYSDEIDMTQLMQFRNQLQLVAKENGVPKLTFMPF 292
                |..|.:||.:|||:|:|:.:||||||.|.||:|::||::.|::|:.:.:..|| ||::|||
Zfish   258 FTGKDHTEPIKGFQKAMVKTMSAALKIPHFGYKDEVDLSQLVRLRSELKGLTESRGV-KLSYMPF 321

  Fly   293 CIKAASIALSKYPIVNSSLDLASESLVFKGAHNISVAIDTPQGLVVPNIKNCQTKTIIEIAKDLN 357
            .|||||:||..:||:|||||....|:.:|.||||.:|:||.|||:|||:||.|..::.|||.:||
Zfish   322 FIKAASLALLHFPILNSSLDENCTSITYKAAHNIGLAMDTSQGLLVPNVKNIQMLSVFEIAVELN 386

  Fly   358 ALVERGRTGSLSPADFADGTFSLSNIGVIGGTYTHPCIMAPQVAIGAMGRTKAVPRFNDKDEVVK 422
            .|...|.:|.|..:|...|||:|||||.|||||..|.|:.|:|||||:|:.:.:||||.||||||
Zfish   387 RLQILGASGQLGTSDLTGGTFTLSNIGSIGGTYAKPVILPPEVAIGALGKIQVLPRFNHKDEVVK 451

  Fly   423 AYVMSVSWSADHRVIDGVTMASFSNVWKQYLENPALFLL 461
            |::|:||||||||:|||.||..|||:|:.||||||..:|
Zfish   452 AHIMNVSWSADHRIIDGATMCRFSNLWRSYLENPASMVL 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5599	NP_573000.1	lipoyl_domain	39..109	CDD:133458	53/69 (77%)
		PLN02528	41..462	CDD:215289	225/442 (51%)
		E3_binding	161..194	CDD:280908	18/32 (56%)
		2-oxoacid_dh	248..461	CDD:278621	121/212 (57%)
dbt	NP_001013533.1	lipoyl_domain	64..137	CDD:133458	55/72 (76%)
		PLN02528	66..493	CDD:215289	225/442 (51%)
		E3_binding	174..206	CDD:280908	18/31 (58%)
		2-oxoacid_dh	278..490	CDD:278621	121/212 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596411
Domainoid	1	1.000	233	1.000	Domainoid score	I2342
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1444
Inparanoid	1	1.050	386	1.000	Inparanoid score	I1986
OMA	1	1.010	-	-		QHG61710
OrthoDB	1	1.010	-	-		D428202at33208
OrthoFinder	1	1.000	-	-		FOG0005815
OrthoInspector	1	1.000	-	-		oto40279
orthoMCL	1	0.900	-	-		OOG6_101891
Panther	1	1.100	-	-	LDO	PTHR43178
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4793
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910