Protein Alignment Dbct and Pdhx

DIOPT Version :10

• Sequence 1: NP_573000.1
• Gene: Dbct / 32441
• FlyBaseID: FBgn0030612
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_780303.1
• Gene: Pdhx / 27402
• MGIID: 1351627
• Length: 501
• Species: Mus musculus
• Alignment Length: 493
• Identity: 135/493 - (27%)
• Similarity: 228/493 - (46%)
• Gaps: 65/493 - (13%)

  Fly     6 LRNGATCWLLRNCISQRAALRRCLHVTSSLD-KTVSFNLSDIGEGIREVTVKEWFVKEGDTVEQF 69
            |..||..|.:     .|.|..|..|.|..|. ..:...:..:...:.:..:.:|..|||:.|...
Mouse    28 LAQGAAAWPV-----DRGASWRWFHSTQLLQADPIKVLMPSLSPTMEQGNIVKWLRKEGEAVSAG 87

  Fly    70 DNLCEVQSDKASVTITSRYDGKITKIHHKIDE----------IALVGKPLLDFDVVNEDED---- 120
            |:|||:::|||.||:.:..||.:.||  .::|          |||         :|.|.||
Mouse    88 DSLCEIETDKAVVTLDANDDGILAKI--VVEEGAKNIQLGSLIAL---------MVEEGEDWKQV 141

  Fly   121 -EPEDSSSSSSSTSSDSSASENEEKQSAEASATPTEGRVIIPATPSVRRLAKEHQLDLAKVPATG 184
             .|:|.|:....:...:....:.:.|....:....:|......:|:.|.:.::|.||.::..|||
Mouse   142 EIPKDVSAPPPVSKPPAPTQPSPQPQIPCPARKEHKGTARFRLSPAARNILEKHSLDASQGTATG 206

  Fly   185 KNGRVLKGDILEF-----LGQVPPG--TNVPHPTLLAKTPSAAPSGAA-------SVSVPADR-- 233
            ..|...|.|.|:.     :|::...  .:.|.|:|.|..|..|.:|.:       .||:|...
Mouse   207 PRGIFTKEDALKLVELKQMGKITESRPASAPPPSLSASVPPQATAGPSYPRPMTPPVSIPGQPNA 271

  Fly   234 ----VEV-LKGVRKAMLKSMTESLK-IPHFAYSDEIDMTQLMQFRNQLQLVAKENGVPKLTFMPF 292
                .|: ...:|:.:.|.:|||.. :||...:.:.|:..:::.|..|   .|::  .|::...|
Mouse   272 AGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRRDL---VKDD--IKVSVNDF 331

  Fly   293 CIKAASIALSKYPIVNSSLDLASESLVFKGAHNISVAIDTPQGLVVPNIKNCQTKTIIEIAKDLN 357
            .|:||::.|.:.|.||.:.|  .|......:.:||||:.|.:||:.|.||:...|.|.|||..:.
Mouse   332 IIRAAAVTLKQMPGVNVTWD--GEGPKQLPSVDISVAVATDKGLITPIIKDAAAKGIQEIADSVK 394

  Fly   358 ALVERGRTGSLSPADFADGTFSLSNIGVIGGTYTHPCIMAPQVAIGAMGRTKAVPRFNDKDE--- 419
            .|.::.|.|.|.|.::..|:||:||:|:.|.......|..||..|.|:||.:.|.:..:.:|
Mouse   395 VLSKKARDGKLMPEEYQGGSFSISNLGMFGIDEFAAVINPPQACILAVGRFRPVLKLTEDEEGNP 459

  Fly   420 -VVKAYVMSVSWSADHRVIDGVTMASFSNVWKQYLENP 456
             :.:..:::|:.|:|.||:|......|...:|..||||
Mouse   460 QLQQHQLITVTMSSDSRVVDDELATRFLETFKANLENP 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbct	NP_573000.1	PLN02528	41..462	CDD:215289	125/457 (27%)
Pdhx	NP_780303.1	PDHac_trf_mito	58..500	CDD:273567	125/458 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..176		3/30 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	228..256		7/27 (26%)