Protein Alignment CG5599 and dlat-1

DIOPT Version :9

• Sequence 1: NP_573000.1
• Gene: CG5599 / 32441
• FlyBaseID: FBgn0030612
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_001369968.1
• Gene: dlat-1 / 179945
• WormBaseID: WBGene00009082
• Length: 507
• Species: Caenorhabditis elegans
• Alignment Length: 447
• Identity: 145/447 - (32%)
• Similarity: 216/447 - (48%)
• Gaps: 71/447 - (15%)

  Fly    54 TVKEWFVKEGDTVEQFDNLCEVQSDKASVTITSRYDGKITKIHHKIDEIAL---VGKPLLDFDVV 115
            ||..|..||||.:.:.|.|||:::|||::...:..:|.:.||  .|.|.:.   :|| ||...|.
 Worm    93 TVVSWQKKEGDQLSEGDLLCEIETDKATMGFETPEEGYLAKI--LIQEGSKDVPIGK-LLCIIVD 154

  Fly   116 NEDE-----DEPEDSSSSSSSTSSDSSASENEEKQSAEASATP-------------------TEG 156
            ||.:     |..:|.:||..|..:...|.| ..|.:|.:..:|                   :.|
 Worm   155 NEADVAAFKDFKDDGASSGGSAPAAEKAPE-PAKPAASSQPSPPAQMYQAPSVPKSAPIPHSSSG 218

  Fly   157 RVIIPATPSVRRLAKEHQLDLAKVPATGKNGRVLKGDILEFLGQVPPGTNVPHPTLLAK----TP 217
            ||  .|:|..::||.|:.|||:.|..:|..||:|..|    |.|.|           ||    |.
 Worm   219 RV--SASPFAKKLAAENGLDLSGVSGSGPGGRILASD----LSQAP-----------AKGATSTT 266

  Fly   218 SAAPSGAASVSVPADRVEVLKGVRKAMLKSMTESLK-IPHFAYSDEIDMTQLMQFRNQLQ-LVAK 280
            :.|.||.....:|      |..:||.:.|.:|||.. |||:..:.||.:..|:|.|.:|. |:||
 Worm   267 TQAVSGQDYTDIP------LSNMRKTIAKRLTESKSTIPHYYLTSEIQLDTLLQVREKLNGLLAK 325

  Fly   281 --ENGVPKLTFMPFCIKAASIALSKYPIVNSSLDLASESLVFKGAH-NISVAIDTPQGLVVPNIK 342
              .....|::...|.|||:::|..:.|..||   ...:|.:.:..| ::|||:.||.||:.|.|.
 Worm   326 GTSGQATKISINDFIIKASALACQRVPEANS---YWMDSFIRENHHVDVSVAVSTPAGLITPIIF 387

  Fly   343 NCQTKTIIEIAKDLNALVERGRTGSLSPADFADGTFSLSNIGVIGGTYTHPCIM-APQVAIGAMG 406
            |...|.:..||.::..|.:|.|.|.|.|.:|..|||::||:|:.|.......|: .||..|.|:|
 Worm   388 NAHAKGLATIASEIVELAQRAREGKLQPHEFQGGTFTVSNLGMFGSVSDFTAIINPPQSCILAIG 452

  Fly   407 --RTKAVPRFNDKDEVVKAYVMSVSWSADHRVIDGVTMASFSNVWKQYLENPALFLL 461
              ..|.||  ::.:...|...|.|:.|.|||.:||...|.:...:|::||.|...||
 Worm   453 GASDKLVP--DEAEGYKKIKTMKVTLSCDHRTVDGAVGAVWLRHFKEFLEKPHTMLL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5599	NP_573000.1	lipoyl_domain	39..109	CDD:133458	21/57 (37%)
		PLN02528	41..462	CDD:215289	145/447 (32%)
		E3_binding	161..194	CDD:280908	13/32 (41%)
		2-oxoacid_dh	248..461	CDD:278621	76/220 (35%)
dlat-1	NP_001369968.1	PDHac_trf_mito	80..507	CDD:273567	143/445 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810