Protein Alignment Dbct and Dbt

DIOPT Version :10

• Sequence 1: NP_573000.1
• Gene: Dbct / 32441
• FlyBaseID: FBgn0030612
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_034152.2
• Gene: Dbt / 13171
• MGIID: 105386
• Length: 482
• Species: Mus musculus
• Alignment Length: 454
• Identity: 223/454 - (49%)
• Similarity: 300/454 - (66%)
• Gaps: 43/454 - (9%)

  Fly    26 RRCLHVTSSLD-KTVSFNLSDIGEGIREVTVKEWFVKEGDTVEQFDNLCEVQSDKASVTITSRYD 89
            |..|...:.|. :.|.|.||||||||||||:|||:|||||||.|||::|||||||||||||||||
Mouse    51 RHSLRTAAVLQGQVVQFKLSDIGEGIREVTIKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYD 115

  Fly    90 GKITKIHHKIDEIALVGKPLLDFDVVNEDEDEPEDSSSSSSSTSSDSSASENEEKQSAEASATPT 154
            |.|.::::.:|:||.|||||:|.:.         ::...|.....::.|..::|....|.....|
Mouse   116 GVIKRLYYNLDDIAYVGKPLIDIET---------EALKDSEEDVVETPAVSHDEHTHQEIKGQKT 171

  Fly   155 EGRVIIPATPSVRRLAKEHQLDLAKVPATGKNGRVLKGDILEFLGQ-----VPPG-----TNVP- 208
                  .|||:|||||.|:.:.|::|..:||:||:||.|||.||.:     :||.     |..|
Mouse   172 ------LATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILSFLEKQTGAILPPSPKSEITPPPP 230

  Fly   209 ------HPTLLAKTPSAAPSGAASVSVPADRVEVLKGVRKAMLKSMTESLKIPHFAYSDEIDMTQ 267
                  .||.:||.|         |....||.|.:.|.:|||:|:|:.:||||||.|.||||:||
Mouse   231 QPKDRTFPTPIAKPP---------VFTGKDRTEPVTGFQKAMVKTMSAALKIPHFGYCDEIDLTQ 286

  Fly   268 LMQFRNQLQLVAKENGVPKLTFMPFCIKAASIALSKYPIVNSSLDLASESLVFKGAHNISVAIDT 332
            |::.|.:|:.||...|: ||:||||.:||||:.|.::||:|:|:|...:::.:|.:|||.:|:||
Mouse   287 LVKLREELKPVALARGI-KLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDT 350

  Fly   333 PQGLVVPNIKNCQTKTIIEIAKDLNALVERGRTGSLSPADFADGTFSLSNIGVIGGTYTHPCIMA 397
            ..||:|||:||.|.:::.|||.:||.|.:.|.:|.|...|...|||:|||||.|||||..|.|:.
Mouse   351 ELGLIVPNVKNVQVRSVFEIAMELNRLQKLGSSGQLGTTDLTGGTFTLSNIGSIGGTYAKPVILP 415

  Fly   398 PQVAIGAMGRTKAVPRFNDKDEVVKAYVMSVSWSADHRVIDGVTMASFSNVWKQYLENPALFLL 461
            |:|||||:|..||:|||:.|.:|.||.:|:||||||||||||.||:.|||:||.||||||..||
Mouse   416 PEVAIGALGAIKALPRFDQKGDVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLL 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbct	NP_573000.1	PLN02528	41..462	CDD:215289	219/438 (50%)
Dbt	NP_034152.2	PLN02528	67..482	CDD:215289	219/438 (50%)
		Critical for association with PPM1K. /evidence=ECO:0000250|UniProtKB:P11182	145..160		2/14 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..252		10/43 (23%)