DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lsd-2 and Plin4

DIOPT Version :9

Sequence 1:	NP_572996.1	Gene:	Lsd-2 / 32437	FlyBaseID:	FBgn0030608	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_011244848.1	Gene:	Plin4 / 57435	MGIID:	1929709	Length:	1649	Species:	Mus musculus

Alignment Length:	359	Identity:	64/359 - (17%)
Similarity:	107/359 - (29%)	Gaps:	97/359 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TGNGTTGNGTAMNDVDQPK----DAKD-LLPHLESLERIIKLPVVNAAWDKSQDVYGKVKGKNRV 69
            ||......|||...:|..|    ..|| :...|.....:.|               |..:|....
Mouse  1085 TGAMNVAKGTAQMGIDTSKTVLTGTKDTVCAGLTGAINVAK---------------GATQGGLDT 1134

  Fly    70 FEWALTAAEDCVTRAVTTAAPFVTKLDRPIAYVDQTLVKGIDKLEVKAPIIKDTPQEIYNQAKSK 134
            .:..|...:|.||..:|.|          |.........|:|..:......|||.......|.:.
Mouse  1135 TKSVLMGTKDTVTTGLTGA----------INVAKGAAQGGLDTTKSVLLGTKDTVTTGLTGAANV 1189

  Fly   135 VIDVVQPHLERVVKFKAAGQQKAASLKDLAWQKANEVLATQYGSLAV------NGVDTTTALAER 193
            ..:.||..|:              :.|::.....:.:.|...|::.|      .|:||:.|....
Mouse  1190 AKETVQMGLD--------------TSKNILMDTKDSICAGATGAITVVKGAAQGGLDTSNAALTG 1240

  Fly   194 LLEYYFPKCESDVEEDNDDKQNAVVQNGKSSENDMPVPASEDPVLHTVQTVGRLSNKISRRVYRN 258
            .:                |.....||....:...|.: ..:|.|...|.:...::..|.:..  :
Mouse  1241 TM----------------DTAKGTVQTSLDTSKHMLI-GMKDTVCAGVTSAMNMAKGIHKNT--D 1286

  Fly   259 VSRQIKQ---VQKGNINDYLSSLIAALKLHQYINFINSSMGTNVEQSGGSSSDACSP-------- 312
            .:|..:.   ...||        :|...:|..::.:.||:       .||.|..|..
Mouse  1287 TTRDTQSSVLAHSGN--------VATNAIHTGVHTVPSSL-------SGSHSIICHEPSIYRATN 1336

  Fly   313 --FGTTTSTTTTTTTSSTSNNKPVVALPHVAKSK 344
              .|....|:|.:....||:......|.||.:.:
Mouse  1337 HGVGQAILTSTESLCCETSSFSDKYGLGHVTEPR 1370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lsd-2	NP_572996.1	Perilipin	40..>287	CDD:281086	40/255 (16%)
Plin4	XP_011244848.1	Perilipin	<177..>255	CDD:367309
		Perilipin	<242..>288	CDD:367309
		COG5412	309..834	CDD:333356
		COG5412	804..1338	CDD:333356	56/325 (17%)
		Perilipin	<1373..1630	CDD:367309
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847356
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840