DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lsd-2 and Plin1

DIOPT Version :9

Sequence 1:	NP_572996.1	Gene:	Lsd-2 / 32437	FlyBaseID:	FBgn0030608	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001295074.1	Gene:	Plin1 / 25629	RGDID:	3351	Length:	518	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	63/249 - (25%)
Similarity:	108/249 - (43%)	Gaps:	36/249 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LPHLES-LERIIKLPVVNAAWDKSQDVYGKVKGKNRVFEWALTAAEDCVTRAVTTAA----PFVT 93
            ||..|: |:|:::||||:...:..|..|...|..:.:......|.|..|..|...||    |.|.
  Rat    14 LPEQENVLQRVLQLPVVSGTCECFQKTYNSTKEAHPLVASVCNAYEKGVQGASNLAAWSMEPVVR 78

  Fly    94 KLDRPIAYVDQTLVKGIDKLEVKAPIIKDTPQEIYNQAKSKV----------IDV-VQPHLERVV 147
            :|.......::...:|:|.||.|.|.::..|::|.::.|..:          |.| :....::|:
  Rat    79 RLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKGTISTRLRSARNSISVPIASTSDKVL 143

  Fly   148 KFKAAGQQKAASL-KDLAWQKANEVLATQYGSLAVNGVDTTTALAERLLEYYFPKCESDVEEDND 211
            ....||.:.|..: |:.|...||    |:.|.||..|.|......|:::||..|          .
  Rat   144 GATLAGCELALGMAKETAEYAAN----TRVGRLASGGADLALGSIEKVVEYLLP----------P 194

  Fly   212 DKQNAVVQNGKSSENDMPVPASEDPVLHTVQTVGRLSNKISRRVYRNVSRQIKQ 265
            ||..:...:|:  :.....|.::..:|..|.|   |:|.:||...:..:|.:|:
  Rat   195 DKVESAPSSGR--QKMQKAPKAKPSLLRRVST---LANTLSRHTMQTTARALKR 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lsd-2	NP_572996.1	Perilipin	40..>287	CDD:281086	60/242 (25%)
Plin1	NP_001295074.1	Perilipin	14..392	CDD:281086	63/249 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	197..217		2/21 (10%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	285..321
		Required for interaction with CIDEC. /evidence=ECO:0000250	291..322
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350911
Domainoid	1	1.000	61	1.000	Domainoid score	I10186
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	53	1.000	Inparanoid score	I5350
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1437332at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto98801
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.900