Protein Alignment Lsd-2 and PLIN2

DIOPT Version :9

• Sequence 1: NP_572996.1
• Gene: Lsd-2 / 32437
• FlyBaseID: FBgn0030608
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: XP_016869748.1
• Gene: PLIN2 / 123
• HGNCID: 248
• Length: 445
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 68/295 - (23%)
• Similarity: 118/295 - (40%)
• Gaps: 45/295 - (15%)

  Fly    35 PHLESLERIIKLPVVNAAWDKSQDVYGKVKGK----NRVFEWALTAAEDCVTRAVTTAAPFVTKL 95
            |....:.|::.||:|::.:|.....|...|.:    ..|.|.|....:...:.|:|:|.|.:.||
Human     8 PQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPIIQKL 72

  Fly    96 DRPIAYVDQTLVKGIDKLEVKAPIIKDTPQEIYNQAKSKVI--------------DVVQPHLERV 146
            :..||..:....||:|::|.:.||:.....:|...||..|.              |.|...:..|
Human    73 EPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGV 137

  Fly   147 V-KFKAAGQQKAASLKDLAWQKANEVLATQYGSLAVNGVDTTTALAERLLEYYFPKCESDVEEDN 210
            : |.|.|........|.:.....|.||.::...|..:||:.....:|.|:|.|.|..|.::|::
Human   138 MDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKE- 201

  Fly   211 DDKQNAVVQNGKSSEN-DMPVPASEDPVLHTVQTVGRLSNKISRRVYRNVSRQIKQVQKGNINDY 274
                      .|..|. |:    .:.|..:.  .:|.||.|:..|.|:....::|:.::
Human   202 ----------AKKVEGFDL----VQKPSYYV--RLGSLSTKLHSRAYQQALSRVKEAKQ------ 244

  Fly   275 LSSLIAALKLHQYINFINSSMGTNVEQSGGSSSDA 309
             .|.....:||..::.|..:. .||..:.....||
Human   245 -KSQQTISQLHSTVHLIEFAR-KNVYSANQKIQDA 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lsd-2	NP_572996.1	Perilipin	40..>287	CDD:281086	62/266 (23%)
PLIN2	XP_016869748.1	Perilipin	6..395	CDD:281086	68/295 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156952
Domainoid	1	1.000	64	1.000	Domainoid score	I10228
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	65	1.000	Inparanoid score	I5366
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1437332at2759
OrthoFinder	1	1.000	-	-		FOG0001967
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14024
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4632
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	8.030