Protein Alignment Lsd-2 and PLIN3

DIOPT Version :9

• Sequence 1: NP_572996.1
• Gene: Lsd-2 / 32437
• FlyBaseID: FBgn0030608
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_005808.3
• Gene: PLIN3 / 10226
• HGNCID: 16893
• Length: 434
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 61/306 - (19%)
• Similarity: 125/306 - (40%)
• Gaps: 48/306 - (15%)

  Fly    10 TGNGTTGNGTAMNDVDQPKDAKDLLPHLESLERIIKLPVVNAAWDKSQDVYGKVKGKNRVFEWAL 74
            :.:|...:|:....|::|.....:      ::|:..:|::::..|.....|...|......:...
Human     2 SADGAEADGSTQVTVEEPVQQPSV------VDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC 60

  Fly    75 TAAEDCV----TRAVTTAAPFVTKLDRPIAYVDQTLVKGIDKLEVKAPIIKDTPQEIYNQAK--- 132
            .|||..|    ..||:.|.|.::||:..||...:...:|:||||...||::...:::....|
Human    61 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELV 125

  Fly   133 -SKVI----------DVVQPHL-ERVVKFKAAGQQKAASLKDLAWQKANEVLATQYGSLAVNGVD 185
             |||.          |.|...| |.|...:.|.|......|.:.......|:.::.|.:.::|||
Human   126 SSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVD 190

  Fly   186 TTTALAERLLEYYFPKCESD---VEEDNDDKQNAVVQNGKSSENDMPVPASEDPVLHTVQTVGRL 247
            |....:|...:.:.|..:::   :....|....|.||..:..::            :.|: :|.|
Human   191 TVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQS------------YFVR-LGSL 242

  Fly   248 SNKISRRVYRNVSRQIKQVQKGNINDYLSSLIAALKLHQYINFINS 293
            |.::.:..|.:...:::..::       .:..|.|:|.|.::.:.:
Human   243 SERLRQHAYEHSLGKLRATKQ-------RAQEALLQLSQVLSLMET 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lsd-2	NP_572996.1	Perilipin	40..>287	CDD:281086	56/268 (21%)
PLIN3	NP_005808.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		4/19 (21%)
		Perilipin	19..411	CDD:281086	58/289 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156955
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1437332at2759
OrthoFinder	1	1.000	-	-		FOG0001967
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14024
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4632
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.980