DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dob and Pnpla4

DIOPT Version :9

Sequence 1:	NP_572995.1	Gene:	dob / 32436	FlyBaseID:	FBgn0030607	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	XP_006257029.1	Gene:	Pnpla4 / 363471	RGDID:	1562200	Length:	259	Species:	Rattus norvegicus

Alignment Length:	253	Identity:	92/253 - (36%)
Similarity:	132/253 - (52%)	Gaps:	23/253 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LSFSGCGFLGIYHVGVAVCLRQHAPQLL--LERIAGASAGALAACCLICDLP--LECMAGDFLRV 69
            ||||.||||||||:|.|..|.:....||  :...||||||||.| .|:...|  :|.........
  Rat    13 LSFSSCGFLGIYHLGAATVLSKRGRGLLCNVTGFAGASAGALVA-TLLLTAPERIEACTRFTFAF 76

  Fly    70 VQEIQRHSLGAFSPWFNLPECLLEGMRSWLPEDAHLLASGRLHISLTRVSDRRNVVMSEFSSRQE 134
            .:|::..:||..:|.::....|..|:...||:.||.||..|||:|:|.... :|.::|.|:.|..
  Rat    77 AEEVRMQALGPLTPGYDFMARLRGGIDEILPQHAHELARERLHVSVTSAVG-QNYLVSNFTCRDN 140

  Fly   135 LLQALMCSCFIPGLSGLVPPQVRGVRYMDGAFSDNLPLLDE-HTVTVSPFCGESDICPRDQNPHL 198
            |:..|:.|||||..:||.|....|...:||..:::||:|.. .|||.|||.|.:|:.|||
  Rat   141 LITVLLASCFIPFYAGLKPMDCAGQLCVDGGLTNSLPVLPTGRTVTFSPFSGRADVSPRD----- 200

  Fly   199 LQLNINWANTCIRLSRR-------NLRRMVRILVPGRADFMANFCQQGYDDTLQFLRR 249
                :.|....:|::::       ||.|:.:.|.|.....|......|..||::||||
  Rat   201 ----LGWPGIYVRVAKQDVMVSMANLVRVQQALFPPSRGMMEAIYGMGMTDTVRFLRR 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dob	NP_572995.1	Pat_iPLA2	7..253	CDD:132857	92/253 (36%)
dob	NP_572995.1	EIN3	<270..>375	CDD:296674
Pnpla4	XP_006257029.1	Pat_PNPLA4	12..256	CDD:132861	92/253 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204225at2759
OrthoFinder	1	1.000	-	-		FOG0000670
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820