DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dob and D1054.1

DIOPT Version :9

Sequence 1:	NP_572995.1	Gene:	dob / 32436	FlyBaseID:	FBgn0030607	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	NP_505749.3	Gene:	D1054.1 / 179492	WormBaseID:	WBGene00008370	Length:	266	Species:	Caenorhabditis elegans

Alignment Length:	271	Identity:	92/271 - (33%)
Similarity:	135/271 - (49%)	Gaps:	27/271 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKIRT-------------RRSLSFSGCGFLGIYHVGVAVCLRQHAPQL--LLERIAGASAGALAA 50
            |||.|             :.:|||||.||||.|:.|.|..|.|....:  .::|.||||||:|.|
Worm     1 MKISTILLKRLNKLEDVSKLALSFSGSGFLGAYNFGAAKRLMQEKKTIGEKVDRFAGASAGSLVA 65

  Fly    51 CCL-ICDLPLECMAGDFLRVVQEIQRHSLGAFSPWFNLPECLLEGMRSWLPEDAHLLASGRLHIS 114
            ..| :....|:........:...:.....||.:|.:.|.|.|:..:..:||.|. ..|.||||||
Worm    66 AILALAPEKLDAAIDTLYSMADHVHAQRFGAMTPGYYLNEQLVTIIDDFLPTDI-ANAQGRLHIS 129

  Fly   115 LTRVSDRRNVVMSEFSSRQELLQALMCSCFIP----GLSGLVPPQVRGVRYMDGAFSDNLPLL-D 174
            :|::....|:::::|.||..|:..|:.||:||    |..| |||.:.....:||..::|||.. |
Worm   130 ITKLKKWENIMINKFDSRDHLISCLLASCYIPMYSMGYKG-VPPIINQEECIDGGMTNNLPTFPD 193

  Fly   175 EHTVTVSPFCGESDICPRDQNPHLLQLNINWANTCIRLSRRNLRRMVRILVPGRADFMANFCQQG 239
            ..|:|.|||..::||||.|.:    ..||.:.....:.|||||.|..|.|.|.....:..:.:.|
Worm   194 VLTITCSPFSSQADICPDDPS----TWNIEFGKQIFKASRRNLYRGARALFPPNRFILKQYYEMG 254

  Fly   240 YDDTLQFLRRN 250
            ..|...|:::|
Worm   255 ISDADIFIKKN 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dob	NP_572995.1	Pat_iPLA2	7..253	CDD:132857	88/252 (35%)
dob	NP_572995.1	EIN3	<270..>375	CDD:296674
D1054.1	NP_505749.3	Pat_PNPLA4	21..266	CDD:132861	88/251 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3773
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204225at2759
OrthoFinder	1	1.000	-	-		FOG0000670
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17075
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.850