DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dob and Pnpla3

DIOPT Version :9

Sequence 1:	NP_572995.1	Gene:	dob / 32436	FlyBaseID:	FBgn0030607	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	XP_006520408.1	Gene:	Pnpla3 / 116939	MGIID:	2151796	Length:	432	Species:	Mus musculus

Alignment Length:	252	Identity:	117/252 - (46%)
Similarity:	164/252 - (65%)	Gaps:	5/252 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RRSLSFSGCGFLGIYHVGVAVCLRQHAPQLLLE--RIAGASAGALAACCLICDLPLECMAGDFLR 68
            |.||||:||||||.||||..:||.:.||.||.:  ...|.|||||.|...:|.|||..:....:.
Mouse     7 RWSLSFAGCGFLGFYHVGATLCLSERAPHLLRDARTFFGCSAGALHAVTFVCSLPLGRIMEILMD 71

  Fly    69 VVQEIQRHSLGAFSPWFNLPECLLEGMRSWLPEDAHLLASGRLHISLTRVSDRRNVVMSEFSSRQ 133
            :|::.:..::|...|:||:.:|:.:|::..||::.|.:.||::|||||||||..||::|||.|:.
Mouse    72 LVRKARSRNIGTLHPFFNINKCIRDGLQESLPDNVHQVISGKVHISLTRVSDGENVLVSEFHSKD 136

  Fly   134 ELLQALMCSCFIPGLSGLVPPQVRGVRYMDGAFSDNLPLLD-EHTVTVSPFCGESDICPRDQNPH 197
            |::.||:||||||..|||:||..||.||:||..|||:|:|| :.|:|||||.||.||||:.::.:
Mouse   137 EVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTN 201

  Fly   198 LLQLNINWANTCIRLSRRNLRRMVRILVPGRADFMANFCQQGYDDTLQFLRRNSLLN 254
            ...:||  .|..:||...||:.:.|.|.|.....|...|.|||.|..:||..|.:.|
Mouse   202 FFHVNI--TNLSLRLCTGNLQLLTRALFPSDVKVMGELCYQGYLDAFRFLEENGICN 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dob	NP_572995.1	Pat_iPLA2	7..253	CDD:132857	115/248 (46%)
dob	NP_572995.1	EIN3	<270..>375	CDD:296674
Pnpla3	XP_006520408.1	Pat_PNPLA3	8..259	CDD:132860	116/251 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	266	1.000	Inparanoid score	I3030
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204225at2759
OrthoFinder	1	1.000	-	-		FOG0000670
OrthoInspector	1	1.000	-	-		mtm8728
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12406
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1585
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.930