DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment opm and ERP3

DIOPT Version :9

Sequence 1:	NP_572994.1	Gene:	opm / 32435	FlyBaseID:	FBgn0264389	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_010266.1	Gene:	ERP3 / 851544	SGDID:	S000002176	Length:	225	Species:	Saccharomyces cerevisiae

Alignment Length:	257	Identity:	60/257 - (23%)
Similarity:	90/257 - (35%)	Gaps:	97/257 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 AEAYDKEMTVYVDAGKTECLYHSVRQGE-TIDFEYQVIDGGHGDLDISFTLLDPIGLVIVSDFKK 90
            |||  ..:|..::.|:.||||....:.: ||.:.:.|..|...|.|:::.:..|      .|..|
Yeast    19 AEA--SPLTFELNKGRKECLYTLTPEIDCTISYYFAVQQGESNDFDVNYEIFAP------DDKNK 75

  Fly    91 PENVHRHEVAKEGDYRFCFDNSFSMFNRKTVFFELIVEREGEELQGDTQWNEADELTGLSRDEY- 154
            |                                  |:||.||. ||  :|:    ..|..:.||
Yeast    76 P----------------------------------IIERSGER-QG--EWS----FIGQHKGEYA 99

  Fly   155 ---YDMKVQD-IMDFIGR--------IRLQLTKARQLQDVLRSHEA---------------RDRN 192
               |..|..| |:|...:        ||.:..|||:.|..||..:.               |..:
Yeast   100 ICFYGGKAHDKIVDLDFKYNCERQDDIRNERRKARKAQRNLRDSKTDPLQDSVENSIDTIERQLH 164

  Fly   193 LAESNFQKV------NH------------WSMVQISAMIGVGLIQVFMLRSIFATGGRMHNL 236
            :.|.|.|..      ||            :|:..|..:||:...|:.:|..||.. .|.||:
Yeast   165 VLERNIQYYKSRNTRNHHTVCSTEHRIVMFSIYGILLIIGMSCAQIAILEFIFRE-SRKHNV 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
opm	NP_572994.1	EMP24_GP25L	33..227	CDD:279450	52/240 (22%)
ERP3	NP_010266.1	EMP24_GP25L	23..218	CDD:395878	53/241 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1693
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22811
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.870