DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment opm and tmed1b

DIOPT Version :9

Sequence 1:	NP_572994.1	Gene:	opm / 32435	FlyBaseID:	FBgn0264389	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_001074109.1	Gene:	tmed1b / 791158	ZFINID:	ZDB-GENE-070112-1112	Length:	226	Species:	Danio rerio

Alignment Length:	223	Identity:	80/223 - (35%)
Similarity:	125/223 - (56%)	Gaps:	10/223 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLSIAALLLGVQDA-EAYDKEMTVYVDAGKTECLYHSVRQGETIDFEYQVIDGGHGDLDISFTLL 77
            ||....||.|..:| ...|.|.|..:.|...||.|.|.....:::.|||||.|  ..:|:.|:::
Zfish    11 LLGYVTLLFGAVNAFSPADTEFTFLLPAASKECFYQSAVHNGSVEIEYQVIAG--AGMDVDFSVV 73

  Fly    78 DPIGLVIVSDFKKPENVHRHEVAKEGDYRFCFDNSFSMFNRKTVFFELIVEREGEELQGDTQWNE 142
            .|.|:.::|:|::.:.||..|..:||||:.||||:||..:.|.||||:|::....:...|.:|
Zfish    74 SPQGIHLISEFRRSDGVHMVEPTEEGDYQICFDNTFSRLSEKMVFFEVILDHPSNDAGADDEW-- 136

  Fly   143 ADELTGLSRDE-YYDMKVQDIMDFIGRIRLQLTKARQLQDVLRSHEARDRNLAESNFQKVNHWSM 206
                .||...| ..:.|:.||.:.:..:..:|.::||:|..||:.|||||||.|.|..:|:.||.
Zfish   137 ----AGLGEPESILEYKLDDIKESMETVHRRLERSRQMQTFLRAFEARDRNLLEDNLWRVSFWSC 197

  Fly   207 VQISAMIGVGLIQVFMLRSIFATGGRMH 234
            |.:..::.|..|||:.||.:|....|::
Zfish   198 VNLLVLLSVAFIQVYTLRRLFDDKRRVY 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
opm	NP_572994.1	EMP24_GP25L	33..227	CDD:279450	71/194 (37%)
tmed1b	NP_001074109.1	EMP24_GP25L	31..218	CDD:279450	71/194 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	159	1.000	Domainoid score	I4046
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4164
OMA	1	1.010	-	-		QHG49398
OrthoDB	1	1.010	-	-		D1292519at2759
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	1	1.000	-	-		mtm6492
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22811
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1790
SonicParanoid	1	1.000	-	-		X1510
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	12.110