DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment opm and Tmed2

DIOPT Version :9

Sequence 1:	NP_572994.1	Gene:	opm / 32435	FlyBaseID:	FBgn0264389	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	XP_036021223.1	Gene:	Tmed2 / 56334	MGIID:	1929269	Length:	208	Species:	Mus musculus

Alignment Length:	220	Identity:	52/220 - (23%)
Similarity:	91/220 - (41%)	Gaps:	18/220 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 MPGLVLLLSIAALLLGVQDAEAYDKEMTVYVDAGKTECLYHSVRQGETIDFEYQVIDGGHGDLDI 72
            |..|..||::.|.||..  |..|    .|.:||...||.:..|..|..:...::|.:||..|:|:
Mouse     1 MVTLAELLALLAALLAT--ASGY----FVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDV 59

  Fly    73 SFTLLDPIGLVIVSDFKKPENVHRHEVAKEGDYRFCFDNSFSMFNRKTVFFELIVEREGEELQGD 137
            ..|..|..|  |....::....:......:|.|:|||.|..|....|.|.|.:.:   ||..:|.
Mouse    60 EITGPDNKG--IYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDI---GEAPKGQ 119

  Fly   138 TQWNEADELTGLSRDEYYDMKVQDIMDFIGRIRLQLTKARQLQDVLRSHEARDRNLAESNFQKVN 202
            ....|..       .:.:|.....:.:.|..:.:.:|..:..|:.:...|...|.:.::...:|.
Mouse   120 DMETEGG-------GDSWDAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVV 177

  Fly   203 HWSMVQISAMIGVGLIQVFMLRSIF 227
            .||..:...::.:.|.|::.|:..|
Mouse   178 LWSFFEALVLVAMTLGQIYYLKRFF 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
opm	NP_572994.1	EMP24_GP25L	33..227	CDD:279450	42/193 (22%)
Tmed2	XP_036021223.1	EMP24_GP25L	23..203	CDD:395878	43/192 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910