back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment opm and TMED7

DIOPT Version :9

Sequence 1:	NP_572994.1	Gene:	opm / 32435	FlyBaseID:	FBgn0264389	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_861974.1	Gene:	TMED7 / 51014	HGNCID:	24253	Length:	224	Species:	Homo sapiens

Alignment Length:	227	Identity:	68/227 - (29%)
Similarity:	105/227 - (46%)	Gaps:	26/227 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WLGMPGL--VLLLSIAALLLGVQDAEAYDKEMTVYVDAGKTECLYHSVRQGETIDFEYQVIDGGH 67
            |..:.|.  ..||::..|:.|...|    .|:|..:.....:|.|..:.||.....|:|||.|||
Human    10 WAAVAGRWGCRLLALLLLVPGPGGA----SEITFELPDNAKQCFYEDIAQGTKCTLEFQVITGGH 70

  Fly    68 GDLDISFTLLDPIGLVIVSDFKKPENVHRHEVAKEGDYRFCFDNSFSMFNRKTVFFELIVEREGE 132
            .|:|.  .|.||.|.|:..:.||..:......:|.|.|:|||.|.||.|..|||:|:..|   ||
Human    71 YDVDC--RLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFDFQV---GE 130

  Fly   133 ELQGDTQWNEADELTGL-SRDEYYDMKVQDIMDFIGRIRLQLTKARQLQDVLRSHEARDRNLAES 196
            :.......|....||.: |........::.::|:....||:              ||:.|:.||.
Human   131 DPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLR--------------EAQGRSRAED 181

  Fly   197 NFQKVNHWSMVQISAMIGVGLIQVFMLRSIFA 228
            ...:|.:||:.:...::.|.:.|||:|:|.|:
Human   182 LNTRVAYWSVGEALILLVVSIGQVFLLKSFFS 213

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.