DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment opm and bub3

DIOPT Version :9

Sequence 1:	NP_572994.1	Gene:	opm / 32435	FlyBaseID:	FBgn0264389	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_001007498.2	Gene:	bub3 / 493224	XenbaseID:	XB-GENE-955683	Length:	330	Species:	Xenopus tropicalis

Alignment Length:	179	Identity:	36/179 - (20%)
Similarity:	69/179 - (38%)	Gaps:	40/179 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 GDLDISFTLLDPIGLVIVSDFKKPENVHRHEVAKEGDYRFCFDNSFSMFNRKTVFFEL-----IV 127
            |..|.:..|.||........|.:|:.|:...|:  || |.....:    .|:.:.::|     :.
Frog   120 GSWDQTVKLWDPRTPCNAGTFSQPDKVYTLSVS--GD-RLIVGTA----GRRVLVWDLRNMGYVQ 177

  Fly   128 EREGEELQGDTQWNEADELTGLSRDEYYDMKVQDIMDFI-GRIRLQ-LTKARQLQDVLRSHEARD 190
            :|....|:..|:...|           :..|...::..| ||:.:: |..:.::|.  :.:..:.
Frog   178 QRRESSLKYQTRCIRA-----------FPNKQGYVLSSIEGRVAVEYLDPSLEVQK--KKYAFKC 229

  Fly   191 RNLAESNFQKVNHWSMVQISAMIGVGLIQVFMLRSIFATGGR--MHNLW 237
            ..|.|:|.:::           ..|..:....|.:.|||||.  ..|:|
Frog   230 HRLKENNIEQI-----------YPVNAVSFHNLHNTFATGGSDGFVNIW 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
opm	NP_572994.1	EMP24_GP25L	33..227	CDD:279450	29/165 (18%)
bub3	NP_001007498.2	WD40	20..302	CDD:421866	36/179 (20%)
		WD40 repeat	23..60	CDD:293791
		WD40 repeat	66..100	CDD:293791
		WD40 repeat	105..140	CDD:293791	5/19 (26%)
		WD40 repeat	147..181	CDD:293791	7/40 (18%)
		WD40 repeat	188..228	CDD:293791	8/52 (15%)
		WD40 repeat	243..280	CDD:293791	9/25 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1693
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900