DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment opm and tmed1a

DIOPT Version :9

Sequence 1:	NP_572994.1	Gene:	opm / 32435	FlyBaseID:	FBgn0264389	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_001003487.1	Gene:	tmed1a / 445093	ZFINID:	ZDB-GENE-040801-229	Length:	226	Species:	Danio rerio

Alignment Length:	219	Identity:	86/219 - (39%)
Similarity:	124/219 - (56%)	Gaps:	11/219 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VLLLSIAALL--LGVQDAEAYDKEMTVYVDAGKTECLYHSVRQGETIDFEYQVIDGGHGDLDISF 74
            |..||...|.  ||....:..|.|.|..:.||.|||.:.:..:..:::.|||||.|  ..||:.|
Zfish     8 VCFLSFLTLCLDLGFTFGQNKDTEFTFLLPAGATECFFQTATKNSSMEVEYQVIAG--SGLDVGF 70

  Fly    75 TLLDPIGLVIVSDFKKPENVHRHEVAKEGDYRFCFDNSFSMFNRKTVFFELIVE-REGEELQGDT 138
            ||:.|.|..:||||:|.:.:|..:..:|||||.|||||||..:.|.|:.|:|:: .|||: :.|.
Zfish    71 TLISPRGYRLVSDFRKSDGIHTVDSTEEGDYRICFDNSFSRISEKMVYVEVIMDGPEGED-EDDE 134

  Fly   139 QWNEADELTGLSRDEYYDMKVQDIMDFIGRIRLQLTKARQLQDVLRSHEARDRNLAESNFQKVNH 203
            .|....|     .::..:.|::||.|.:..:...|.::||||..||:.|||||.|.|.|..:|:.
Zfish   135 DWAALAE-----PEDSLEYKLEDIRDSMDAVHKSLERSRQLQTTLRAFEARDRYLLEDNLWRVSF 194

  Fly   204 WSMVQISAMIGVGLIQVFMLRSIF 227
            ||...:..||.|.|.||:.||.:|
Zfish   195 WSCASLLVMISVALTQVYTLRRLF 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
opm	NP_572994.1	EMP24_GP25L	33..227	CDD:279450	78/194 (40%)
tmed1a	NP_001003487.1	EMP24_GP25L	31..219	CDD:279450	79/196 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	159	1.000	Domainoid score	I4046
eggNOG	1	0.900	-	-		E1_KOG1693
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4164
OMA	1	1.010	-	-		QHG49398
OrthoDB	1	1.010	-	-		D1292519at2759
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	1	1.000	-	-		mtm6492
orthoMCL	1	0.900	-	-		OOG6_108563
Panther	1	1.100	-	-	O	PTHR22811
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1510
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.840