DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment opm and tmed5

DIOPT Version :9

Sequence 1:	NP_572994.1	Gene:	opm / 32435	FlyBaseID:	FBgn0264389	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_956697.1	Gene:	tmed5 / 393374	ZFINID:	ZDB-GENE-040426-1302	Length:	225	Species:	Danio rerio

Alignment Length:	224	Identity:	91/224 - (40%)
Similarity:	138/224 - (61%)	Gaps:	21/224 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VLLLSIAALLLGVQDAEAY----DKEMTVYVDAGKTECLYHSVRQGETIDFEYQVIDGGHGDLDI 72
            ||...:|.|.:.|..|.|:    |.:.|..:.||:.||.:.::::..:::.||||:||  ..||:
Zfish     7 VLRACVACLSVCVSLASAFSQSLDSDFTFTLAAGRRECFFQTMKKDASLEIEYQVLDG--ASLDV 69

  Fly    73 SFTLLDPIGLVIVSDFKKPENVHRHEVAKEGDYRFCFDNSFSMFNRKTVFFELIVEREGEELQGD 137
            .|.|..|.|.:|.||::|.:.||..| .:||||.|||||:||..:.|.:|||||::..||:.:.:
Zfish    70 DFQLNSPSGHIIASDYRKSDGVHTVE-TEEGDYMFCFDNTFSAVSEKVIFFELILDNMGEDEESE 133

  Fly   138 TQWNE----ADELTGLSRDEYYDMKVQDIMDFIGRIRLQLTKARQLQDVLRSHEARDRNLAESNF 198
             .|..    ||.|         |||::||||.|..::.:|.|:.|:|.:||:.|||||||.|||:
Zfish   134 -DWKAYVQGADLL---------DMKLEDIMDTINNVKSRLGKSLQIQTLLRAFEARDRNLQESNY 188

  Fly   199 QKVNHWSMVQISAMIGVGLIQVFMLRSIF 227
            ::||.||...:..|:.|..:||::|||:|
Zfish   189 ERVNLWSCTNVLVMVIVSGVQVYLLRSLF 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
opm	NP_572994.1	EMP24_GP25L	33..227	CDD:279450	82/197 (42%)
tmed5	NP_956697.1	EMP24_GP25L	32..218	CDD:279450	83/199 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	159	1.000	Domainoid score	I4046
eggNOG	1	0.900	-	-		E1_KOG1693
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4996
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4164
OMA	1	1.010	-	-		QHG49398
OrthoDB	1	1.010	-	-		D1292519at2759
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	1	1.000	-	-		mtm6492
orthoMCL	1	0.900	-	-		OOG6_108563
Panther	1	1.100	-	-	O	PTHR22811
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1790
SonicParanoid	1	1.000	-	-		X1510
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.870