DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment opm and TMED2

DIOPT Version :9

Sequence 1:	NP_572994.1	Gene:	opm / 32435	FlyBaseID:	FBgn0264389	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_001308374.1	Gene:	TMED2 / 10959	HGNCID:	16996	Length:	208	Species:	Homo sapiens

Alignment Length:	221	Identity:	50/221 - (22%)
Similarity:	92/221 - (41%)	Gaps:	31/221 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLLSIAALLLGVQDAEAYDKEMTVYVDAGKTECLYHSVRQGETIDFEYQVIDGGHGDLDISFTLL 77
            ||:.:||||..|..       ..|.:||...||.:..|..|..:...::|.:||..|:|:..|..
Human     7 LLVLLAALLATVSG-------YFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGP 64

  Fly    78 DPIGLVIVSDFKKPENVHRHEVAKEGDYRFCFDNSFSMFNRKTVFFELIVER--EGEELQ----G 136
            |..|  |....::....:......:|.|:|||.|..|....|.|.|.:.:..  :|::::    |
Human    65 DNKG--IYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEGGG 127

  Fly   137 DTQWNEADELTGLSRDEYYDMKVQDIMDFIGRIRLQLTKARQLQDVLRSHEARDRNLAESNFQKV 201
            ||                :|.....:.:.|..:.:.:|..:..|:.:...|...|.:.::...:|
Human   128 DT----------------WDAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRV 176

  Fly   202 NHWSMVQISAMIGVGLIQVFMLRSIF 227
            ..||..:...::.:.|.|::.|:..|
Human   177 VLWSFFEALVLVAMTLGQIYYLKRFF 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
opm	NP_572994.1	EMP24_GP25L	33..227	CDD:279450	42/199 (21%)
TMED2	NP_001308374.1	EMP24_GP25L	23..203	CDD:366467	43/198 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910