|
Fly 4 LLNPLKYGDHFYELYT----------NSTRRKMQHDRKVLTKRK-SRKDKSAAAMAAAAAAAVLE 57
||:.....|.:..:|| :||......::|:|.|:| .||.||.:.:...:.:..:|
Mouse 67 LLSGRALADRYRRIYTTALSDRDQAGSSTGHPASRNKKILNKKKLKRKQKSKSKVKTRSKSENVE 131
Fly 58 GNAGAGGLVNPLDPPLVKEQLMILPSFPVAHIELDPNASKFAVFSAIRSTVLEAETRYSLFQEGG 122
.. :|:|. |:|..|.|.|.::..:|..|||.:.:.:......
Mouse 132 NT-------------------VIIPD-----IKLHSNPSAFNIYCNVRHCVLEWQKKETSLAAAS 172
Fly 123 APSGQSGSNQKKWSNNVNSACCMMCAHSCMISNLLDCSCHAHMAMHGAVGPGNAGPGGPVGVLVD 187
..|.|||
Mouse 173 KNSVQSG---------------------------------------------------------- 179
Fly 188 GRIPAPVPVVVGGPGLPAEKRPRRDSANSDADSDTEEPTEREPVYATVPLIVGAGLRSLFELIAD 252
::|||.||.:...|: .:|.|:..||..:||||.:
Mouse 180 -----------------------------ESDSDEEEESREPPI--KLPKIIEVGLCEVFELIKE 213
Fly 253 ARHVHPLLCTKALKALLDVIQGQQPESFKLEPEELINPLYDLLLDLATMPAALNSATGAEANWSA 317
.|..||.||.::|:|||:|:||||||..:.||.|::..|:.|||::......:|.:|| .:.:|
Mouse 214 TRFSHPSLCLRSLQALLNVLQGQQPEGLQSEPPEVLESLFQLLLEITVRSTGMNDSTG--QSLTA 276
Fly 318 MACAALLGLCIARGDTGKMLKAIAAMLMTPRQLSAQIVQLPVVLATLQHTVISAALNKPTRPDFH 382
::||.|..|..:.|:||:.|:||:|:|......:.|.:|:|.:|.:||.:|.:..:.|....|:.
Mouse 277 LSCACLFSLVASWGETGRTLQAISAILTNNGSHACQTIQVPTILNSLQRSVQAVLVGKIQVQDWF 341
Fly 383 SHGVPHNSLIDEFPVKLPPLSTGAPITSPAMACDGVFVYLLYGGTLLKIGTGFGGSYKGHIYAQN 447
|:|:...:|:.::|:|...:... ....:..||.|:|||....|.|||:|:.|:.:||||...
Mouse 342 SNGIKKAALMHKWPLKEVSVDED---DQCLLQNDGFFLYLLCKDGLYKIGSGYSGTVRGHIYNST 403
Fly 448 EDFSH--ERSAWLGYSGGQLYFR------RTCRRSAGDQLQMVGLDTLAIKAMSPLSMLHMREGL 504
....: |:.:||||:.|.|.:| .|..|.:.:.|:..| |:. |...| .||.
Mouse 404 SRIRNRKEKKSWLGYAQGYLLYRDLNNHSMTAIRISPETLEQDG--TVL------LPDCH-TEGQ 459
Fly 505 NYVLFTDDDSLHAICSNRDDTLVVKKLNLYHNSYNIDPPPF---ELPLQLARKKFRTLGYAAFED 566
| :||||.:.::.|.::|||..||: .:.....|. ||.|:||||.....|.:.|:.
Mouse 460 N-ILFTDGEYINQIAASRDDGFVVR-------IFATSTEPVLQQELQLKLARKCLHACGISLFDL 516
Fly 567 ELLNQYQIQRIQSAHNSFEPKLPAPCRDADVDVMGMACGKEFGLVRASNGRVYYYGKSAALGLKC 631
| :.:......| |.:..::| .|:||.|::.:||::||.||..:||:|.
Mouse 517 E-------KDLHIISTGF---------DEESAILG--AGREFALMKTANGKIYYTGKYQSLGIKQ 563
Fly 632 VGRTPTL-KLTELVISKAANIVHVAVGHDGIHALLVNDDGTVFFAGTARRGEDGDSSKNRRQPKA 695
.| |:. |..||.|:|:..|||.:|||||.|||||.:||:|||.|:|.:||||:|:|:|||.|.
Mouse 564 GG--PSAGKWVELPITKSPKIVHFSVGHDGSHALLVAEDGSVFFTGSASKGEDGESTKSRRQSKP 626
Fly 696 VKPKKMTKIDGHVVVHAACNNGTSAFVTKTGKLIMYGKDTAHCDAMGFVSELLEQHVTKVALGKA 760
.||||:.|::|.:||:.|||||:|:.::|.|:|.|:|||..:.|:...||:|....||:||:|||
Mouse 627 YKPKKIIKMEGKIVVYTACNNGSSSVISKDGELYMFGKDAIYSDSSSLVSDLKGHFVTQVAMGKA 691
Fly 761 HCVALNAKGQLFSFGLNNKGQCGRIFNKLQPVKDVPPFASSSTAAACFASL-LPLDKRLKLDFST 824
|...|...|::::||:||||||||....:. :....|...:.|.|....| ..||: |.:.|.
Mouse 692 HTCVLMKNGEVWTFGVNNKGQCGRDTGAMN--QGGKGFGVENMATAMDEDLEEELDE--KDEKSM 752
Fly 825 LCDYDDHNLVQGQCRVCVICRECTGYNVSCVSALNVPLDQRLAGSICPCGHGDAGCAKCGLCAAC 889
:|....|.....||.||.:|.:||||..||||: ....|:.|.||.||.|::|||.||.|.||
Mouse 753 MCPPGMHKWKLEQCMVCTVCGDCTGYGASCVSS---GRPDRVPGGICGCGSGESGCAVCGCCKAC 814
Fly 890 IALQDSDEAK--------TELKP---------PPSDVQQ----RQQRSKTLIMRR---------- 923
....|..||: .|:.| |..:::: ||:..:..::||
Mouse 815 ARELDGQEARQRGILDAVKEMIPLDLLLAVPVPGVNIEEHLQLRQEEKRQRVIRRHRLEDGRGPL 879
Fly 924 -------------------------KERKGELETGAAGGGAATPTDLDKDPPRVAPLAPQLLQLT 963
|.::.:.:.|:...| :||..::....|..::..
Mouse 880 VFAGPIFMNHREQALARLRSHPAQLKHKRDKHKDGSGDRG-------EKDASKITTYPPGSVRFD 937
Fly 964 SSSPVVQVACGLHHTVVLTLAGEVYTFGSNQYGQLGSGDLQPVSGPVRVQ-VPGAISQVAAGSNH 1027
.....|||:||.||:|||...|:|||||..|:||||.||:.....|..|| :||..:||.|||||
Mouse 938 CELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTAGSNH 1002
Fly 1028 TVLLTSKGMVYTFGNYQKGQLGRLPSDYGLKPPPQDDDSPVGAGSDGGAGGSPTVAPVGMPGPER 1092
|.:|...|.|:|||::.||||||
Mouse 1003 TAVLLMDGQVFTFGSFSKGQLGR------------------------------------------ 1025
Fly 1093 SQSPANVQPSGSKEMPPLLPVLTQRQKFLWNCSPGAVFGLGPCYGKKVTWIGANGDQTFIKIDES 1157
|:|.:. .||..|..:..:|..||:|.|||||:|||||::|||:
Mouse 1026 ----------------PILDIP------YWNAKPAPMPNIGSKYGRKATWIGASGDQTFLRIDEA 1068
Fly 1158 LITAQMLPKMHVVANKKTILLIP---SIPLSFHTLSINRRDGSCTAHYRGQTNFVKLMQAQPEQQ 1219
||.:.:|....:.|:|..|.|:| |.|..|..|.||:.||||
Mouse 1069 LINSHVLATSEIFASKHIIGLVPASISEPPPFKCLLINKVDGSC--------------------- 1112
Fly 1220 QPEINSNLDVAVTPVADSPAHASTSSLLAALTGTATAGVPINEQMSRSMHEARNQIFEEQLPEVG 1284
:..|...:|.|...|
Mouse 1113 --------------------------------------------------KTFNDSEQEDLQGFG 1127
Fly 1285 SSAAAAAVAAPGTPVSAGSVPRSRRGGKQGTSSPEPIPSPPQLAFTMDPTYNVLWVFDGAARKLR 1349
..:||.|:|||.|..:.|:|.
Mouse 1128 --------------------------------------------VCLDPVYDVLWRFRPSTRELW 1148
Fly 1350 CHNVVASDINDSDANAATYR-SLLSPELSLPDRVDSRVARSQASLNLLACLDILTSAQDNIPGCF 1413
|:|.|.:|.....|.....| |:|||||:||....:...||.|:|::|.|||.|.:.||...|
Mouse 1149 CYNAVVADARLPSATDMQSRCSILSPELALPTGSRALTTRSHAALHILGCLDTLAAMQDLKMG-- 1211
Fly 1414 EQPLLKQTQQTAETQA-------GEFQVVNRFDNFGGGWGYSGHSVEAIRFSADTDIVICGFGMF 1471
:..|:: |||| .::.|||||::.|||||||.||||||||||||||::.|.|:|
Mouse 1212 ----IASTEE--ETQAVMKVYSKEDYSVVNRFESHGGGWGYSAHSVEAIRFSADTDILLGGLGLF 1270
Fly 1472 GGRGEYSCKLKLFDLGGDGGGYEKEGILISETKEVPYECGARSKHHILLPKPVSAVAGRWYLVWA 1536
||||||:.|:|||:||.|||.:|.:|.|::||..:.|:|.||.|:.::..:||...||.||:.||
Mouse 1271 GGRGEYTAKIKLFELGPDGGDHETDGDLLAETDVLAYDCAAREKYAMMFDEPVLLQAGWWYVAWA 1335
Fly 1537 RIAGPSSDCGSCGQASVTTEDQVVFSFKSSKKANNGTDVNSGQIPAILYRLVTQDCKQTPA-QMD 1600
|::||||||||.||||:||:|.|:|.||||||:|||||||:||||.:||||.|.|...:.. |..
Mouse 1336 RVSGPSSDCGSHGQASITTDDGVIFQFKSSKKSNNGTDVNAGQIPQLLYRLPTSDGSTSKGKQQT 1400
Fly 1601 ADPVQRISRAFANSVSRECFESLVVLLSWSWDCFKLQLREERDRSRPLQLQQS---LQYLGYVIK 1662
::||..:.|:||.:||.||||||:.:|.|||....|.:.|.|. .:..|...: |:.|.:|..
Mouse 1401 SEPVHILKRSFARTVSVECFESLLSILHWSWTTLVLGVEELRG-LKGFQFTATLLDLERLRFVGT 1464
Fly 1663 SCLRLLRKYTIEIYPQRNSSTSVATGGGSNAAHGSGVVTTAKSVQSKPNKDKNTPRVVGNAGVMA 1727
.||||||.||.|||| |..|.|:|..:.:|
Mouse 1465 CCLRLLRVYTCEIYP---------------------VSATGKAVVEETSK--------------- 1493
Fly 1728 KYFGDPSTSVAPAMISSASSGGAPSTSASAAVAPGSGTPVTRKTNMENIQLAECIGNVRALLIGI 1792
||||||..|.||..|
Mouse 1494 --------------------------------------------------LAECIGKTRTLLRKI 1508
Fly 1793 F---CDDIFKDIATD-EGY-----ELSLEILDECHLSFVACFDAFYPTSSLKWNCLCDLLAQMDR 1848
. .|.....:..| :|| .|...:|.|||.:|.|||.:||||.:|:|.||||||..:|:
Mouse 1509 LSEGVDHCMVKLDNDPQGYLSQPLRLLEAVLQECHNTFTACFHSFYPTPALQWACLCDLLNCLDQ 1573
Fly 1849 G-------ALHSRLLSAILAGLCSPSVKLRATFSLLSAAGNERQSIISPSDNSGLPMLSSTDAHP 1906
. ...||||:|:::.||..||||.:.|.:........:||:....... .||..|.
Mouse 1574 DIQEANFKTSSSRLLAAVMSALCHTSVKLTSLFPIAYDGEVLLRSIVKQVSTEN----DSTLVHR 1634
Fly 1907 YPVLVEQMIYRTQQEKSDFLSNSWTFKDVLVRLLDIIASPIRSRIEAIYSRSLGSLGYPGGKDCV 1971
:|:||..|...:|.|:: :|...:|::||.::|.|:..|:|:.:.. ..:..
Mouse 1635 FPLLVGHMEKLSQSEEN--ISGMTSFREVLEKMLVIVVLPVRNSLRR-------------ESELF 1684
Fly 1972 NQGLIDNCCHLLARVLAEIVYQTAMG---EYDKLFMPPRTLHSTGA---RFARCDVSRTWNTGNF 2030
:..|:.|.|.|||.:::|:. .:|:| ..|.| .:|||..| ||.:....|:|||||.
Mouse 1685 SSHLVSNTCGLLASIVSELT-ASALGSEVRVDGL----NSLHSVKASANRFTKTSQGRSWNTGNG 1744
Fly 2031 GPDAIAFAVDRPGVAIAGAMVYSGSGSYDYQLELLYDNT---ADLQPQHKWETLESVSGSYDQDA 2092
.||||.||||:||:.:.|..||.|.|.::|:||:|.|:: .|....|:|.:||.|.|:|..|.
Mouse 1745 SPDAICFAVDKPGIVVVGFAVYGGGGIHEYELEVLVDDSEHAGDSTHSHRWTSLELVKGTYTTDD 1809
Fly 2093 VHNDLAEIKFDHPVHIKENARYALRLCSQGARTCSGDAGMPAVRGPCGAQFHFYACDLSFNGTTP 2157
..:|:|||:.|..|.:|||.:||:||.:.|:||.:||.||..|:.|.|..|.|..|.||.|||..
Mouse 1810 SPSDIAEIRLDKVVPLKENVKYAVRLRNYGSRTANGDGGMTTVQCPDGVTFTFSTCSLSSNGTNQ 1874
Fly 2158 ARGQLPCILYYSTPMKQDGHSASGRTGDGSNVATHLEDRIMLLGPHEVSTRDTALQIAADITKKC 2222
.|||:|.||||.:....| |:.:::.....|......||.:.:.:.:..
Mouse 1875 TRGQIPQILYYRSEFDGD-----------------LQSQLLSKANEEDKNCSRALSVVSTVVRAA 1922
Fly 2223 TELLILARNAMAASCSPSDNSSNHTQTIDSEHNITPIEEHMDINWANNSRTAALPTAIDPQLSTA 2287
.:|| ..|:| :|:: || |:|
Mouse 1923 KDLL---HRALA---------------VDAD----------DI----------------PEL--- 1940
Fly 2288 RDLGKRIESFSKGLMETLKFDKRSTNPFEMEIEIGATEVEESADLRNGQSQSVSQSQSQSQSVPI 2352
Mouse 1941 ----------------------------------------------------------------- 1940
Fly 2353 NGNERTADFEFAEQSAQQSMPQHLHSDSEEAPLEVAGMAAGGGVSVADGSGGVAGVGSQAAAVQL 2417
Mouse 1941 ----------------------------------------------------------------- 1940
Fly 2418 LEVFNLAASNMFHTLLPLVYAHIANLACSDPKSSVQILGLIKEILPHIAALNQLHVSKDQRQPEP 2482
|::|::|..||||:.|:|..:|.:.||.:|::.||::::||.:|.|| |:...|
Mouse 1941 -----LSSSSLFSMLLPLIIAYIGPVAAAIPKVAVEVFGLVQQLLPSVAILN-------QKYAPP 1993
Fly 2483 AIFATQTSGSGNSN------SSSTTSNHYCVVESDHPYKSASISSYRVEFPPCVQWLTIEFDPQC 2541
|....|::.|...| |:.||||||.|:||:||||.|.:..|:|.||.||:|:||||||||
Mouse 1994 AFNPNQSTDSTTGNQPEQGLSACTTSNHYAVIESEHPYKPACVMHYKVTFPECVRWMTIEFDPQC 2058
Fly 2542 GTAQLEDYLLLSIPMRPASQAPPVPHVDDYLEQADNNVNGAGDRRRNTGGGIAGSGAAPNTHQRS 2606
||||.||.:.|.||:|.. :|:|.|
Mouse 2059 GTAQSEDVIRLLIPVRTI---------------------------QNSGYG-------------- 2082
Fly 2607 ASVQLTMASCCRSPGCGNAPGSAAAPSSMPLRSQDPNDREWIVVKKFNTASTWLHNVLILPGNCV 2671
..|.|...|...|:.:||::.:|.|...||:||||..
Mouse 2083 ----------------------------AKLTSVHENLNSWVELKKYSGSSGWPTMVLVLPGNEA 2119
Fly 2672 EFSLETASLYAQDPHNNRYGFKCLVVGYD-NPTSINASNSCLIRLEQELAYLGGMCSANLMKKEL 2735
.|||||||.|.:|...:.|||||..:||: :| ..:..:|:||:|||.|||:|:|.||||:|
Mouse 2120 LFSLETASDYVKDDKASFYGFKCFAIGYEFSP----GPDEGVIQLEKELANLGGVCAAALMKKDL 2180
Fly 2736 NLPDDKDV-EDMSGIEE----TINTHHTLLSKGFALSEPQLTVHQALESYLPIGSQSNERQFLKD 2795
.||...:: ||:..:|| ...||..:|.||.|||... |:.:|||..||:..||||:.||.|
Mouse 2181 ALPVGNELEEDLEILEEAALQVCKTHSGILGKGLALSHSP-TILEALEGNLPLQIQSNEQSFLDD 2244
Fly 2796 FISGAPGSSGARLAAWLQPESRLDPNKCELNTITEPLRYGWPSQVTVTIRDQYGDAVLVPELKVE 2860
||:..|||||.|||.||||:|..||.|..|....:.:|.|||:.:||..:|||||.|.||.:|||
Mouse 2245 FIACVPGSSGGRLARWLQPDSYADPQKTSLILNKDDIRCGWPTTITVQTKDQYGDVVHVPNMKVE 2309
Fly 2861 IKAIPTGSGPNGSATGTGTSCTSVAEVSAPG-PNLWMRRASRDTWGWGGMAPPP-RINYEPTVKD 2923
:||:|............|..|..: || |: ..||.....:||:|.|. .::|||.:..
Mouse 2310 VKAVPVSQKKTSLQQDQGKKCQRI-----PGSPS---AAASSADMTFGGLASPKLDVSYEPMIVK 2366
Fly 2924 KMVFKAITFMKPYANYSFEELRYASPVQTRVTELLNAKDMEDGTFSVQWTPSSVGAYCLAVTIDG 2988
:..:.|||.||.|.||||||||:|||...|.:|.:..:...|||:...|||.::|.|.:.|||||
Mouse 2367 EARYIAITMMKVYENYSFEELRFASPTPKRPSENMLIRVNNDGTYCANWTPGAIGLYTVHVTIDG 2431
Fly 2989 IPLEEVYRVDVKE---GILPPPTQRNSAQRRPQAPSKLRRFQARHSSGLRIRSHPTLQSEQVGVV 3050
|.::....|.||: |::||.||....:..|| |:|:|:|.|:.|:||||||||:|||||:|:|
Mouse 2432 IEIDAGLEVKVKDPPKGMIPPGTQLVKPKADPQ-PNKIRKFVAKDSAGLRIRSHPSLQSEQIGIV 2495
Fly 3051 RVGGVISFIDEIENDDGVWLRLSTESIRQHC-TMGWYPTEAWCLQFNQHLARMLLQPV------- 3107
||.|.|:|||||.|||||||||:.|:|:::. .|..| ||||||.|||||.:.||.||
Mouse 2496 RVNGTITFIDEIHNDDGVWLRLNEETIKKYVPNMNGY-TEAWCLSFNQHLGKSLLVPVDNIFNAS 2559
Fly 3108 ------------------------TD---KEVNP---------------VRKGVGAEEDVEEQP- 3129
|| |::|. :|.|.|..:.|:..|
Mouse 2560 QGVRDLDVFSWTSKAFFPQEPKTNTDDFFKDMNSCGPQEATMQERDHPFLRGGPGMYKVVKTGPS 2624
Fly 3130 -------------PV---------------------------------TPSASGEA--------- 3139
|: ..|..|||
Mouse 2625 GHNIRSCPNLRGIPIGMLVLGNKVKAVGEVTNSEGAWVQLDKNSMVEFCESDEGEAWSLARDRGG 2689
Fly 3140 ---------------SPEPEPDPSP----------------------------VLSPAKTKPGRF 3161
:.:| |.||| ||..|..:....
Mouse 2690 NQYLRHEDEQVLLDQNSQP-PPPSPFSVQAFNKGASCSAQGFDYGLGNNKVLTVLPTAGDQLSAI 2753
Fly 3162 LSGHQST---------------------NPFLY--------------PAKHADLAEREA------ 3185
|:..||. :||:: |:: :||.||.
Mouse 2754 LNSIQSRPNLPAPSIFDQAAKPPSSLVHSPFVFGQPLSFQQRQLQNSPSR--NLASRERIYKHLG 2816
Fly 3186 -------------QVQEER-------------------------EKEEEQVDDEDADDREPE-QE 3211
::|.:| .|.:..|....||.::|. .|
Mouse 2817 VAGPASALSSLSHKLQGDRGTISTSSRPVSTSGKSELPSKHSRSVKPDGHVSRTPADQKKPRGTE 2881
Fly 3212 ALPAVELLPAHIGSAIAGVVGGGAIKLQA-------------LQ------KWFKGDAVDGPQPLT 3257
.|.|.|.| ::...|.||:: || :...|...:.|.|.:
Mouse 2882 GLSASESL----------MLKSDAAKLRSDSHSRSLSPNHNTLQTLKSDGRTSSGFRAESPGPGS 2936
Fly 3258 PSHSP-------PLAGVSVRELVRAMGGQDS----------------PRGNGNRSQQEQDPEFSL 3299
.|.|| |.:..|.....|:...||. ||..........||: :|
Mouse 2937 RSSSPKPKPLPTPRSSPSGASSPRSSSPQDKNLPQKSTAPAKTKLDPPRERSKSDSYTLDPD-TL 3000
Fly 3300 ASMRRPNYSASQTAALLSTPKHTPKRSAVVASETSGLEDEL------------SLLQITTTTT-- 3350
...:.|.....:..:....||..||. ..::.|.|:.. .::::.|::|
Mouse 3001 RKKKMPLTEPLRGRSTSPKPKPVPKD----PKDSPGSENRAPSPHVVQENLHSEVVEVCTSSTLK 3061
Fly 3351 -----------------------------GQGEQQSELQL----------ATTSTASSASKRN-- 3374
|:...:.|.:: |...|.....|.|
Mouse 3062 TNGVTDSTCDDSGDLKSVDEGSNKVHFSIGKAPLKDEQEMRASPKISRKCANRHTRPKKEKSNFL 3126
Fly 3375 -------PMGPIKRAMPPSFAESIRAVFAALLWHEGVVHDAMACASFLKFHPGLPKEGATVVTRR 3432
.:.|.|:||.||.||..|||||:.|||||:|||||||:|||||:|.|.||.|.: |.
Mouse 3127 FKGDGTKSLEPAKQAMSPSVAECARAVFASFLWHEGIVHDAMACSSFLKFNPDLSKEHAPI--RS 3189
Fly 3433 GESGDPRLQLSREQKAQQRHSVEVANAGNYLNIRP-----STLETLTKSGNCSLHNRSKYRKNLL 3492
..:..|..: .:|.|.:.|||:|:::|.|..||.| |.:.::.|:...|:.......:...
Mouse 3190 SLNSQPPTE-EKEIKLKNRHSLEISSALNMFNIAPHGPDISKMGSINKNKVLSMLKEPPLHEKCE 3253
Fly 3493 SGGGGAINSGDDTAQKLQALPEM--------VSVLPPALRCLVYLWEQICSGCVQIVQSNALEQR 3549
.| |.:|..|| .|.||..|:.||..||.|....::....|.:
Mouse 3254 DG-------------KSEATFEMSMHHTMKSKSPLPLTLQHLVAFWEDISLATIKAASQNMI--- 3302
Fly 3550 EPRLLSPGSRDLNGDADTEGKEGKNSDQASAGEKDLGRKCKRKKK-------------------- 3594
..|||| .|..:.||.:..::.:..|| |:|:|
Mouse 3303 ---FPSPGS-----CAVLKKKECEKENKKTKKEK------KKKEKTEIRPRGNLFGEMAQLAVGG 3353
Fly 3595 -DDGSWCEICELFLPMPVTYHMRIAHPGCGKSAKGKGYNSVGIFCEGWAGNCGEGGKGASSWFLM 3658
:..:.||:|....|.|||||||.||||||:.|.|:||||:|.||.|||||||:||.|.|:|:|:
Mouse 3354 PEKDTICELCGESHPYPVTYHMRQAHPGCGRYAGGQGYNSIGHFCGGWAGNCGDGGMGGSTWYLV 3418
Fly 3659 CDPCRDRYLASCRSANNINSAARQLESSAAEGNELNLFGVKSTTLIANAEVYTTMRENATFLLEL 3723
||.||::||...::| |..:::.|..:..: ||:...:...|.:..::.||.|||.|
Mouse 3419 CDRCREKYLREKQAA-----AREKVKQSRRKPMQ-----VKTPRALPTMEAHQVIKANALFLLSL 3473
Fly 3724 CSSSSSASGAAGSLAATSSSSKRSPQQMSVVAMPVVIEHQLGNSDLKPSTSRCSRMARLSGSKFC 3788
.| ||..|.....|.:.....:|:|.| |.|:..|....|..:..|:..
Mouse 3474 SS------------AAEPSILCYHPAKPFQSQLPIVKE---GVSEDLPVKMPCLYLQTLARH--- 3520
Fly 3789 PGVGSGAFRKSFVGGPPTAPENVWLAPESFACLECLGTAGHEDLPYEMFGLGPNSNDNGYDRPLS 3853
..::||| ...:| |..:....|. ...:|.....:.|:::.|.::.|
Mouse 3521 -------HHENFVG---YQDDN--LFQDEMRYLR------STSVPAPYISVTPDASPNVFEEP-- 3565
Fly 3854 EISYESCEPNNYDMLSGSLAPGTTAAASVGGGNLSK---FHRSYSMGQGWASLAQHNHPPPHHPQ 3915
|.|...| |.:...:.:...:|:| |.||||: ..::::
Mouse 3566 -------ESNMKSM------PPSLETSPITDTDLAKRTVFQRSYSV-----VASEYD-------- 3604
Fly 3916 QQHHQQQQMNLQLQQHQAPPVDGQPKVVYRRRNNSTSEGDGSLLICYPSEHLRRLVPQKLLASVS 3980
:||...| .:.|.:.|||.||.....||.|:.:||..|.||:
Mouse 3605 -------------KQHSILP--ARVKAIPRRRVNSGDTEVGSSLLRHPSPELSRLI--------- 3645
Fly 3981 VMQTASGEGTGKDHATGTLGLDQSAGQNGGGNLLLTRPAMAFITQKHELDRLRAAMRRSLRIAAC 4045
..|:: .|.|:.. ...|.:||:.|.|:|:.|..||:::||.:||
Mouse 3646 -----------SAHSS------LSKGERN-----FQWPVLAFVIQHHDLEGLEIAMKQALRKSAC 3688
Fly 4046 RIYALQALNWLLRSVTQGVCLHDLMWWFVSSLNPTGGHQPVERGEEASEP--------------- 4095
|::|::|.||||.:|.|...|||::|.||::|.|: |||..|:..|.
Mouse 3689 RVFAMEAFNWLLCNVIQTTSLHDILWHFVAALTPS----PVEAEEDEDEDNKSNKENAEQEKDTR 3749
Fly 4096 ALEHPVAYTQISGRFAHLITQSLHVFLQSVADLTLHLPLGSPLQRVAIQCFGIRFRQADHQFLHS 4160
..|||::...|:|..||.:..:.|..||:::||.:.||.||.||::|::|:.::|:|:||||||.
Mouse 3750 VCEHPLSDIVIAGEAAHPLPHTFHRLLQTISDLMMSLPSGSSLQQMALRCWSLKFKQSDHQFLHQ 3814
Fly 4161 SHVFGNISKILSKSDEQNDAMAVSTILKPDCDVEHNQVHSVATG--GSSGAGARLLCYTDLAGMF 4223
|:||.:|:.|||||| |.|.|.:...||.:| ..|.....::|..||..:.
Mouse 3815 SNVFHHINNILSKSD--------------DGDSEESFSISVQSGFEAMSQELCIVMCLKDLTSIV 3865
Fly 4224 EVTVSSRPAMAESLTDNSTETFWESDEEDRNKCKIIELSLTK-LNYACRYLLVHIDNSRDIQNKV 4287
::..||||||..||||.||||||||.:||:||.|.|.::..| :| .||:.||:|||||:.|||
Mouse 3866 DIKTSSRPAMIGSLTDGSTETFWESGDEDKNKTKNITINCVKGIN--ARYVSVHVDNSRDLGNKV 3928
Fly 4288 LNVVFYAGQSLGDTNIIKSADVDPKACSWISAKICDDSCTHFRLELHGPENTLRVRQIKLLG--- 4349
.::.|..|:::.:...||..|:|.:...|:::::........::||.||||||||||:|:||
Mouse 3929 TSMTFLTGKAVEELCRIKQVDLDSRHIGWVTSELPGGDNQIIKIELKGPENTLRVRQVKVLGWKD 3993
Fly 4350 ---LPIGGAVGSDDSSDHKHQPHLRLSHASRIQQQICEAETLRVFRLITGQVFGKLISNVSSDLV 4411
..|.|.:. ||..||:.|||||||||||||.||||||| |.|..
Mouse 3994 GESTKIAGQIS-----------------ASVAQQRSCEAETLRVFRLITSQVFGKLI---SGDAE 4038
Fly 4412 P----PDSAGIGPPSGGAASTSLLADSLDLREHMVGILFSRSKLSHLQKQVIVHIVHAIRKEAQR 4472
| .:.|.:..|.|.....:..:|: ||:||||||:||||||::|||||..|||.|||.||.|
Mouse 4039 PTPEQEEKALLSSPEGEEKVYNATSDA-DLKEHMVGIIFSRSKLTNLQKQVCAHIVQAIRMEATR 4102
Fly 4473 AKEDWELANLAHVLKQSPQQQTAPALAASASCESTPERSRAPDTYCFEMLSMVLALSGSVVGRSY 4537
.:|:|| |.:.......:.|: :...:.|.||||:||||||||||.|||.|
Mouse 4103 VREEWE-----HAISSKENANSQPS-----------DEDASSDAYCFELLSMVLALSGSNVGRQY 4151
Fly 4538 LSQQHGLLRDLLGLLHTGSDRVQRQVTALLRRILPEITPESFAELLGVQRLPPADYSIAHQSASD 4602
|:||..||:||..||||.|.|||||||:||||:|||:||...|.::||:.|||||.|....|...
Mouse 4152 LAQQLTLLQDLFSLLHTASPRVQRQVTSLLRRVLPEVTPNRLASIIGVKSLPPADISDIIHSTEK 4216
Fly 4603 FDMSRLGLLDIFLAVIAKSLQLQVKVKTTVASTGPSGSGGVSGSSSGNGGAVLKAGQQEKTPAFV 4667
.|.::||:||:||..|||:|.:|:|.|.|..: |.:|::.|.|...:
Mouse 4217 GDWNKLGILDMFLGCIAKALTVQLKAKGTTIT-------GTAGTTVGKGVTTV------------ 4262
Fly 4668 RLWSSLDLSVQQLRSRPPTGEPGTTDPFQFDALPPRK-ESKRNLNQRWFLNGVISTKQAESIISL 4731
|.|..|::...|: || .|::.|...|:.:|.||.|
Mouse 4263 ------------------------TLPMIFNSSYLRRGES------HWWMKGSTPTQISEIIIRL 4297
Fly 4732 IRDLASGKLSEKWSQITKAAIAESVLNLTRLEEIYRSPEHCTKTSTLWLALASLCVLERDHVEKL 4796
|:|:|:|.|||.||::||.||||:::.||::||.:|||..|..|:.|||||||||||::|||::|
Mouse 4298 IKDMAAGHLSEAWSRVTKNAIAETIIALTKMEEEFRSPVRCIATTRLWLALASLCVLDQDHVDRL 4362
Fly 4797 SSGQWSKLCDTR---PLCSNHDDGETAAIIQCETCGSLCGDCDRFLHLNRKTRSHKRTVCKEEEE 4858
|||:|......: |:|.|||||||||||.|..||:||.||||||||:|:|::|:|.|.|||||
Mouse 4363 SSGRWMGKDGQQKQMPMCDNHDDGETAAIILCNICGNLCTDCDRFLHLHRRTKTHQRQVFKEEEE 4427
Fly 4859 AIRVELHESCGRTKLFWLLALADSKTLKAMVEFRDGSHTIISGPQEAVGRCRFCGLTGNSGLLEI 4923
||:|:|||.|||||||||:|||||||:|||||||:.:....:...|| |||||....:.|..:
Mouse 4428 AIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTGKPTTSSSEA---CRFCGSRSGTELSAV 4489
Fly 4924 GNVCADAQCQEYAANSCLKTKPCGHACGGVTGERKCLPCLQHVCHTRENELAEELRDPKLTQDAD 4988
|:||:||.|||||..:|.||.||||.||||..|..||||| |.| ::.|..|: ||||
Mouse 4490 GSVCSDADCQEYAKIACSKTHPCGHPCGGVRNEEHCLPCL-HGC----DKSATTLK-----QDAD 4544
Fly 4989 DMCMICFVEALSCAPSIHLECGHVFHYHCCKAVLEKRWSGPRITFGFSLCPICKADIQHPLLSDI 5053
|||||||.||||.||:|.|:|.||||..||:.|||.||.||||||||..|||||..|.|.:|.|:
Mouse 4545 DMCMICFTEALSAAPAIQLDCSHVFHLQCCRRVLENRWLGPRITFGFISCPICKNKINHIVLKDL 4609
Fly 5054 LEPINGLKQDVKRKALMRIKYEGVVKDTDSKNV---------NMTQLAMDRYAYYVCFKCQKAYY 5109
|:||..|.:||:||||||::|||:.| |:.: :....||:|||||||:||:|||:
Mouse 4610 LDPIKELYEDVRRKALMRLEYEGLHK---SEAITTPGVRFYNDAAGYAMNRYAYYVCYKCRKAYF 4671
Fly 5110 GGEARCDAEI--GEKFDPEELVCGGCSDVARAQMCPKHGTDFLEYKCRYCCSVAVFFCFGTTHFC 5172
|||||||||. |:.:||.||:||.||||:|||||||||||||||||||||||||||||||||||
Mouse 4672 GGEARCDAEAGQGDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFGTTHFC 4736
Fly 5173 DTCHDDFQRLTNIPKVKLPQCPAGPKAKQLLGDECPLHVMHPPTGEEFALGCGVCRNAQTF 5233
:.|||||||:|:|||.:||.||||||.|||.|.||||||:||||||||||||||||||.||
Mouse 4737 NACHDDFQRMTSIPKEELPHCPAGPKGKQLEGTECPLHVVHPPTGEEFALGCGVCRNAHTF 4797
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