Protein Alignment hiw and mycbp2

DIOPT Version :9

• Sequence 1: NP_001285258.1
• Gene: hiw / 32429
• FlyBaseID: FBgn0030600
• Length: 5233
• Species: Drosophila melanogaster
• Sequence 2: XP_031752927.1
• Gene: mycbp2 / 100379925
• XenbaseID: XB-GENE-998752
• Length: 4723
• Species: Xenopus tropicalis
• Alignment Length: 5786
• Identity: 1934/5786 - (33%)
• Similarity: 2702/5786 - (46%)
• Gaps: 1621/5786 - (28%)

  Fly     4 LLNPLKYGDHFYELYTNSTRRKMQ------HDRKVLTKRK-SRKDKSAAAMAAAAAAAVLEGNAG 61
            ||:.....|.:..:||.:...:.|      .::|:::|:| .||.|:.:
 Frog     3 LLSGRALADRYRHIYTAAVSDREQQAGQSGRNKKIISKKKLKRKQKTKS---------------- 51

  Fly    62 AGGLVNPLDPPLVKEQLMILPSFPVAHIELDPNASKFAVFSAIRSTVLE---AETRYSLFQEGGA 123
            .|...|.:|.   :|....:|.     ::|..|.|.|.|:..:|..|||   .||...|..:...
 Frog    52 KGKTRNKVDN---QENAFFIPD-----LKLHSNPSAFNVYCNVRHCVLEWQRKETSLVLSAKNSV 108

  Fly   124 PSGQSGSNQKKWSNNVNSACCMMCAHSCMISNLLDCSCHAHMAMHGAVGPGNAGPGGPVGVLVDG 188
            .||:|
 Frog   109 QSGES------------------------------------------------------------ 113

  Fly   189 RIPAPVPVVVGGPGLPAEKRPRRDSANSDADSDTEEPTEREPVYATVPLIVGAGLRSLFELIADA 253
                                          |||.||.: :||: ..:|.|:..||..:||||.:.
 Frog   114 ------------------------------DSDDEEES-KEPL-IKLPKIIEIGLCEVFELIKET 146

  Fly   254 RHVHPLLCTKALKALLDVIQGQQPESFKLEPEELINPLYDLLLDLATMPAALNSATGAEANWSAM 318
            |..||.||.::|:|||:|:||||||..:.||.|::..|..|:|::.......|.:||  ...:|:
 Frog   147 RFSHPSLCLRSLQALLNVLQGQQPEGLQSEPPEVLESLLQLILEITVRSTGSNDSTG--QTLTAV 209

  Fly   319 ACAALLGLCIARGDTGKMLKAIAAMLMTPRQLSAQIVQLPVVLATLQHTVISAALNKPTRPDFHS 383
            :||.|..|.::.|:|||:|:||:|:|......:.|.:|:|.:|.:||.:|.:..:.|....|:.:
 Frog   210 SCACLFSLVVSWGETGKILQAISAILTNNGSHACQNIQVPTILNSLQRSVQAVLVGKIQIQDWFT 274

  Fly   384 HGVPHNSLIDEFPVKLPPLSTGAPITSPAMACDGVFVYLLYGGTLLKIGTGFGGSYKGHIYAQNE 448
            .|:...:|:.::.::..|:......   .:..||.|:|||....|.|||:|:.|:.:||||....
 Frog   275 SGIKKAALMQKWSLRDIPVDEDEQC---LLQSDGFFLYLLCKDGLYKIGSGYSGTVRGHIYNSTS 336

  Fly   449 DFS--HERSAWLGYSGGQLYFR------RTCRRSAGDQLQMVGLDTLAIKAMSPLSMLHMREGLN 505
            ...  .|:.:||||:.|.|.:|      .|.:|...:.|:..|  |:.:...:       .:|.|
 Frog   337 RIKSRREKKSWLGYAQGYLLYRDTSNQGMTAKRINPETLEQDG--TVTVPDGN-------TDGQN 392

  Fly   506 YVLFTDDDSLHAICSNRDDTLVVKKLNLYHNSYNIDPPPF---ELPLQLARKKFRTLGYAAFEDE 567
             :||:|.:.::.|.:::||..||:       .:.....|.   ||.|:||||.....|.:.|:.|
 Frog   393 -ILFSDGEFINQIAASKDDGFVVR-------IFATSTEPVLQQELQLKLARKCLHACGISLFDLE 449

  Fly   568 LLNQYQIQRIQSAHNSFEPKLPAPCRDADVDVMGMACGKEFGLVRASNGRVYYYGKSAALGLKCV 632
                   :.:......|         |.::.|:|  .|:||.|::.::|:|||.||..:||:| .
 Frog   450 -------KDLHIISTGF---------DEELAVLG--AGREFALMKTASGKVYYTGKYQSLGIK-Q 495

  Fly   633 GRTPTLKLTELVISKAANIVHVAVGHDGIHALLVNDDGTVFFAGTARRGEDGDS--SKNRRQPKA 695
            |...|.|..||.|:|:..||..:|||||.||||..|||:|||.|||.:||||:|  ||:|||.|.
 Frog   496 GGPSTGKWVELPITKSPKIVQFSVGHDGSHALLTADDGSVFFTGTASKGEDGESSKSKSRRQSKP 560

  Fly   696 VKPKKMTKIDGHVVVHAACNNGTSAFVTKTGKLIMYGKDTAHCDAMGFVSELLEQHVTKVALGKA 760
            .|||||.|:||.:||..|||||:|:.::|.|:|.|:|||..:.|:...|::|....||:||:|||
 Frog   561 YKPKKMMKMDGKIVVATACNNGSSSIISKDGELYMFGKDAIYSDSSNLVTDLKGHVVTQVAMGKA 625

  Fly   761 HCVALNAKGQLFSFGLNNKGQCGRIFNKLQPVKDVPPFASSSTAAACFASLLPLDKRL------K 819
            |...|..||::::||:||||||||....:.  :....|...:.|.|       :|:.|      |
 Frog   626 HTCVLTKKGEVWTFGVNNKGQCGRDTGAMN--QGGKAFGVENMATA-------MDEDLEEELDDK 681

  Fly   820 LDFSTLCDYDDHNLVQGQCRVCVICRECTGYNVSCVSALNVPLDQRLAGSICPCGHGDAGCAKCG 884
            .:.|.:|....|.....||.||.:|.|||||..||||:   ....|:.|.||.||.|::||..||
 Frog   682 DEKSMMCPPRMHKWKLEQCMVCTVCGECTGYGASCVSS---GRPDRVPGGICGCGSGESGCGVCG 743

  Fly   885 LCAACIALQDSDEAKT------------------ELKPPP-----SDVQQRQQRSKTLIMRR--- 923
            .|.||....|..||:.                  :..|.|     ..:|.||:..:..:.||
 Frog   744 CCKACARELDGQEARQRGILDAVKEMIPLDLLLGKAVPVPGVNIDEHLQLRQEDKRQRVNRRHRI 808

  Fly   924 -KERKGELETGAAGGGA------------------ATPTDL---------------DKDPPRVAP 954
             :.|.|....|..|...                  :.|..|               :||..::..
 Frog   809 DEGRGGNKPNGDLGPFVFPGPNFMKHREQALARLRSLPAQLKHKRDKKKDEGREQGEKDASKITT 873

  Fly   955 LAPQLLQLTSSSPVVQVACGLHHTVVLTLAGEVYTFGSNQYGQLGSGDLQPVSGPVRVQ-VPGAI 1018
            ..|..::.......|||:||.||:|:|...|:|||||..|:||||.||:.....|..:| :||..
 Frog   874 YPPGAVRFDCELRAVQVSCGFHHSVILMENGDVYTFGYGQHGQLGHGDVSCRGCPTLIQALPGPS 938

  Fly  1019 SQVAAGSNHTVLLTSKGMVYTFGNYQKGQLGRLPSDYGLKPPPQDDDSPVGAGSDGGAGGSPTVA 1083
            :||.||||||.:|...|.|:|||::.||||||
 Frog   939 TQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGR--------------------------------- 970

  Fly  1084 PVGMPGPERSQSPANVQPSGSKEMPPLLPVLTQRQKFLWNCSPGAVFGLGPCYGKKVTWIGANGD 1148
                                     |:|.|.      .||..|..:..:|..||:|.||:||:||
 Frog   971 -------------------------PILDVP------YWNAKPAPMPNIGSKYGRKATWVGASGD 1004

  Fly  1149 QTFIKIDESLITAQMLPKMHVVANKKTILLIPSI---PLSFHTLSINRRDGSCTAHYRGQTNFVK 1210
            |||::|||:||.:.:|....:.|::..|.|:|:.   |..|..|.||:.||:|...
 Frog  1005 QTFLRIDEALINSHVLATSEIFASRHIIGLVPAYMTEPPPFKCLLINKVDGNCATF--------- 1060

  Fly  1211 LMQAQPEQQQPEINSNLDVAVTPVADSPAHASTSSLLAALTGTATAGVPINEQMSRSMHEARNQI 1275
                                                                          |..
 Frog  1061 --------------------------------------------------------------NDS 1063

  Fly  1276 FEEQLPEVGSSAAAAAVAAPGTPVSAGSVPRSRRGGKQGTSSPEPIPSPPQLAFTMDPTYNVLWV 1340
            .:|.|...|                                            ..:||.::|:|.
 Frog  1064 EQEDLQGFG--------------------------------------------VCLDPIHDVIWR 1084

  Fly  1341 FDGAARKLRCHNVVASDINDSDANAATYR-SLLSPELSLPDRVDSRVARSQASLNLLACLDILTS 1404
            |.|:.::|.|:|.|.:|.....|.....| |:|||||:||....:...||.|:|::|.|||.|.:
 Frog  1085 FQGSTKELWCYNAVIADSRLPSAPDMQLRCSILSPELALPIGQKAVTTRSHAALHILGCLDTLAA 1149

  Fly  1405 AQDNIPGCFEQPLLKQTQQTAETQAGE-FQVVNRFDNFGGGWGYSGHSVEAIRFSADTDIVICGF 1468
            .||...|.  ..:.::||...:..:.| :.|||||::.|||||||.||||||||.|||||::.|.
 Frog  1150 MQDLKMGV--SSIEEETQSVMKVYSKEDYSVVNRFESHGGGWGYSAHSVEAIRFCADTDILLGGL 1212

  Fly  1469 GMFGGRGEYSCKLKLFDLGGDGGGYEKEGILISETKEVPYECGARSKHHILLPKPVSAVAGRWYL 1533
            |:|||||||:.|:|||:||.|||.:|.:|.|::||..:.|:|.||.|:.::..:||...||.||:
 Frog  1213 GLFGGRGEYTAKIKLFELGPDGGDHETDGDLLAETDVLAYDCAAREKYAMMFDEPVLLQAGWWYV 1277

  Fly  1534 VWARIAGPSSDCGSCGQASVTTEDQVVFSFKSSKKANNGTDVNSGQIPAILYRLVTQDCKQTPAQ 1598
            .|||::||||||||.||||:||:|.|||.||||||:|||||||:||||.:||||.|.|...|..:
 Frog  1278 AWARVSGPSSDCGSHGQASITTDDGVVFQFKSSKKSNNGTDVNAGQIPQLLYRLPTSDGSATKGK 1342

  Fly  1599 -MDADPVQRISRAFANSVSRECFESLVVLLSWSWDCFKLQLREERDRSRPLQLQQSLQY------ 1656
             ...:||..:.|:||.:||.:|||||:.:|.|||....|.:.|       |:..:..||
 Frog  1343 PQTTEPVHILKRSFARTVSVDCFESLLSILHWSWTTLVLGVEE-------LRSLKGFQYTATLLD 1400

  Fly  1657 ---LGYVIKSCLRLLRKYTIEIYPQRNSSTSVATGGGSNAAHGSGVVTTAKSVQSKPNKDKNTPR 1718
               |.:|...|||||:.|..||||                     |..|.|:|..:.:|
 Frog  1401 LERLRFVGTCCLRLLKVYICEIYP---------------------VSATTKAVVEETSK------ 1438

  Fly  1719 VVGNAGVMAKYFGDPSTSVAPAMISSASSGGAPSTSASAAVAPGSGTPVTRKTNMENIQLAECIG 1783
                                                                       ||||||
 Frog  1439 -----------------------------------------------------------LAECIG 1444

  Fly  1784 NVRALLIGIF---CDDIFKDIATD-EGY---ELSL--EILDECHLSFVACFDAFYPTSSLKWNCL 1839
            ..|.||..|.   .|:....:..| |||   .:||  .:|.|||.:|.|||.:||||.:|:|.||
 Frog  1445 KTRTLLRKILSEGVDNCMTKLDNDPEGYLSQPMSLLEAVLQECHNTFTACFHSFYPTPALQWACL 1509

  Fly  1840 CDLLAQMDRGALH-------SRLLSAILAGLCSPSVKLRATFSLLSAAGNE---RQSI--ISPSD 1892
            ||||..:|:....       ||||:|:::.||:.||||.:.|.:  |...|   |..:  :|..:
 Frog  1510 CDLLNCLDQDIQEANFKPSSSRLLAAVMSALCNTSVKLTSIFPI--AYDGEVLLRSMVKQVSTEN 1572

  Fly  1893 NSGLPMLSSTDAHPYPVLVEQMIYRTQQEKSDFLSNSWTFKDVLVRLLDIIASPIRSRIEAIYSR 1957
            ::.|       ||.:|:||..|...:|.|::  :|...:|::||.::|.|:..|:|:.:..
 Frog  1573 DTAL-------AHRFPLLVSAMEKLSQTEEN--VSGITSFREVLEKMLVIVVLPVRNSLRR---- 1624

  Fly  1958 SLGSLGYPGGKDCVNQGLIDNCCHLLARVLAEIVYQTAMGEYDKLFMPPRTLHSTGA---RFARC 2019
                     ..:..:..|:.|.|.|||.:::|:.......|.|.|    .:|||..:   ||.:.
 Frog  1625 ---------ENELFSSHLVSNTCGLLASIVSELTASALGSEVDGL----NSLHSVKSSPNRFTKT 1676

  Fly  2020 DVSRTWNTGNFGPDAIAFAVDRPGVAIAGAMVYSGSGSYDYQLELLY---DNTADLQPQHKWETL 2081
            ...|:|||||..||||.|:||:||:.:.|..||.|.|.::|:||:|.   |::.|....|:|.:|
 Frog  1677 SQGRSWNTGNGSPDAICFSVDKPGLVVVGFCVYGGGGIHEYELEVLVDDSDHSGDAAHSHRWTSL 1741

  Fly  2082 ESVSGSYDQDAVHNDLAEIKFDHPVHIKENARYALRLCSQGARTCSGDAGMPAVRGPCGAQFHFY 2146
            |.:.|:|..|...:|:|||:.|..|.:|||.:||:||.:.|:||.:||.||..|:......|.|.
 Frog  1742 ELMKGTYTTDDSPSDIAEIRLDKAVPLKENMKYAVRLRNYGSRTANGDGGMTTVQCSDNVTFTFS 1806

  Fly  2147 ACDLSFNGTTPARGQLPCILYYSTPMKQDGHSASGRTGDGSNVATHLEDRIMLLGPHEVSTRDTA 2211
            :|.||.|||...|||:|.:|||.:....|                 |:.:::.....|......|
 Frog  1807 SCSLSSNGTNQTRGQIPQVLYYRSEFDGD-----------------LQSQLLSKANEEDKNCSRA 1854

  Fly  2212 LQIAADITKKCTELLILARNAMAASCSPSDNSSNHTQTIDSEHNITPIEEHMDINWANNSRTAAL 2276
            |.:...:|:...:||   ..|:|               :|:|          ||
 Frog  1855 LAVVNAVTRAAKDLL---HRALA---------------VDAE----------DI----------- 1880

  Fly  2277 PTAIDPQLSTARDLGKRIESFSKGLMETLKFDKRSTNPFEMEIEIGATEVEESADLRNGQSQSVS 2341
                 |:|
 Frog  1881 -----PEL--------------------------------------------------------- 1883

  Fly  2342 QSQSQSQSVPINGNERTADFEFAEQSAQQSMPQHLHSDSEEAPLEVAGMAAGGGVSVADGSGGVA 2406
                                                                             
 Frog  1884 ----------------------------------------------------------------- 1883

  Fly  2407 GVGSQAAAVQLLEVFNLAASNMFHTLLPLVYAHIANLACSDPKSSVQILGLIKEILPHIAALNQL 2471
                            |::|::|..||||:.|:|..:|.:.||::|::..|::::||.:|.|||.
 Frog  1884 ----------------LSSSSLFSMLLPLLIAYIGPVAAAIPKAAVEVFSLVQQLLPSVAILNQK 1932

  Fly  2472 HVSKDQRQPEPAIF-ATQTSGSGNSN-----SSSTTSNHYCVVESDHPYKSASISSYRVEFPPCV 2530
            :.        |.:| ..|::.|...|     |:.|||:||.|:||:||||.||:..::|.||.||
 Frog  1933 YA--------PPVFNPNQSTDSTTGNQPEQLSACTTSSHYAVLESEHPYKPASVMQFKVAFPECV 1989

  Fly  2531 QWLTIEFDPQCGTAQLEDYLLLSIPMRPASQAPPVPHVDDYLEQADNNVNGAGDRRRNTGGGIAG 2595
            :|:::||||||||||.||.|.|.||.|                    |.:            ::|
 Frog  1990 RWISVEFDPQCGTAQSEDVLRLMIPGR--------------------NFH------------LSG 2022

  Fly  2596 SGAAPNTHQRSASVQLTMASCCRSPGCGNAPGSAAAPSSMPLRSQDPNDREWIVVKKFNTASTWL 2660
            .|.....|:...|                                      |:.||||:.::.|.
 Frog  2023 FGPKFPVHESLNS--------------------------------------WVEVKKFSGSTGWP 2049

  Fly  2661 HNVLILPGNCVEFSLETASLYAQDPHNNRYGFKCLVVGYD-NPTSINASNSCLIRLEQELAYLGG 2724
            .:|||||||...|||||||.|.:|...:.|||||..:||: :|    .|:..:|:||:|||.|||
 Frog  2050 TSVLILPGNEAVFSLETASDYVKDEKASFYGFKCFAIGYEYSP----GSDEGIIQLEKELANLGG 2110

  Fly  2725 MCSANLMKKELNLPDDKDV-EDMSGIEE----TINTHHTLLSKGFALSEPQLTVHQALESYLPIG 2784
            .|:|.||||:|.||...:: ||:..:||    ...||..:|.||.|||... |:.:|||..||:.
 Frog  2111 TCAAALMKKDLALPVGSELEEDLEIVEEAALQVCKTHSGILGKGLALSHSP-TILEALEGSLPLQ 2174

  Fly  2785 SQSNERQFLKDFISGAPGSSGARLAAWLQPESRLDPNKCELNTITEPLRYGWPSQVTVTIRDQYG 2849
            .||||:.||:|||:..|||||.|||.||||:|..||.|..|....:.:|.|||:.:||..:||||
 Frog  2175 IQSNEQSFLEDFITCVPGSSGGRLARWLQPDSYADPQKTSLILNKDDVRCGWPTTITVQTKDQYG 2239

  Fly  2850 DAVLVPELKVEIKAIPTGSGPN--------------GSATGTGTSCTSVAEVSAPGPNLWMRRAS 2900
            |.|.||.:|||:||:|......              ||.:.|.||.|.:.
 Frog  2240 DVVHVPNMKVEVKAVPVSQKKTSLQQEQVKKFPRIPGSPSTTNTSGTDMT--------------- 2289

  Fly  2901 RDTWGWGGMAPPPRI--NYEPTVKDKMVFKAITFMKPYANYSFEELRYASPVQTRVTELLNAKDM 2963
                 :||: |.|::  :|||.:..:..:.|||.||.|.||||||||||||:..|.:|.:..:..
 Frog  2290 -----FGGL-PSPKLDASYEPMIVKEARYIAITMMKAYENYSFEELRYASPMPKRPSENMLIRVN 2348

  Fly  2964 EDGTFSVQWTPSSVGAYCLAVTIDGIPLEEVYRVDVKE---GILPPPTQRNSAQRRPQAPSKLRR 3025
            .|||:...|||.:||.|.:.||||||.::....|.||:   |::||.||....:..|| |:|:|:
 Frog  2349 NDGTYCANWTPGAVGLYTIHVTIDGIEIDAGLEVKVKDPPKGMVPPGTQLVKPKSEPQ-PNKVRK 2412

  Fly  3026 FQARHSSGLRIRSHPTLQSEQVGVVRVGGVISFIDEIENDDGVWLRLSTESIRQHC-TMGWYPTE 3089
            |.|:.|:||||||||:|||||:|:|:|.|.|:|:|||.|||||||||:.|:::::. .|..| .|
 Frog  2413 FVAKDSAGLRIRSHPSLQSEQIGIVKVNGTIAFVDEIHNDDGVWLRLNDETVKKYVHNMNGY-NE 2476

  Fly  3090 AWCLQFNQHLARMLLQPV------------------TDK-------------------------- 3110
            ||||.|||||.:.||.||                  |.|
 Frog  2477 AWCLSFNQHLGKSLLAPVDNIFYASQGARDFDVFSWTSKAFISQEQACISDEVLKARCSQEVTMQ 2541

  Fly  3111 --EVNPVRKGVGAEEDVEEQP--------------PV---------------------------- 3131
              ||..:|.|.|..:.|:..|              |:
 Frog  2542 EHEVPVLRSGPGLYKVVKTGPSGHNIRSCPNLRGIPIGMLVLGNKVKAVGEVVGSEGTWVQLDKN 2606

  Fly  3132 ------------------TPSAS--------------GEASPEPEP------------------- 3145
                              .||.:              |..:|.|.|
 Frog  2607 SMVEFCENDEGEAWSLARDPSGNQYLRHEDEQIILDQGSQTPPPSPFTIQMFHRSTSGNIVSGFD 2671

  Fly  3146 -----------------------DPSPVLSPAKTKP-----------GRFLSGHQSTNPFLYPAK 3176
                                   .|:|.:.....||           |:..|..|..:|...|:.
 Frog  2672 YGLGNNKGDQLSAILNSIQSRPNFPTPSIFDQAAKPPSSLVNSPFVFGQSPSFQQPQSPLQNPSS 2736

  Fly  3177 HADLAEREA------------------------------------------QVQEEREKEEEQVD 3199
             :.:|.||:                                          :|:.:..|.:.::.
 Frog  2737 -SSVASRESIHQPKAAPASAFSSLAFKQKDDKGHFAKTTSAVNKSDLPSKNRVESKSPKPDGRIS 2800

  Fly  3200 DEDADDREPE-QEALPAVELL-------------------PAHIGSAIA---GVVGGGAIKLQAL 3241
            ..:||.::|: .|.|.|.|.|                   |.|....|.   |.|..|   |:|
 Frog  2801 RSNADQKKPKNNEGLTASESLLLKSDAAKLRSDSHSRSSSPNHNTLQILKTDGKVNSG---LRA- 2861

  Fly  3242 QKWFKGDAVDGPQPLT-PSHSPPLAGVS--------VRELVRAMGGQ-----DSPRGNGNRSQQE 3292
            :....|.....|:|.| |:..|..:|.|        .:.|.:...|.     :.||.........
 Frog  2862 ESPGPGSRSSSPKPKTVPAGKPNTSGASSPRSASPQEKSLPQKTSGPSKSKLEPPRERSKSDSYT 2926

  Fly  3293 QDPEFSLASMRRPNYSASQTAALLST---PKHTPK----------------------RSAVVA-- 3330
            .||:    ::|:.....::.....||   ||..||                      .|.||.
 Frog  2927 LDPD----TLRKKKVPLTEPLRGRSTSPKPKIIPKDAKPAGGSENRAPSPHVVQENLHSEVVEVC 2987

  Fly  3331 ------------------SETSGLEDELSLLQITTTTTGQGEQQSELQLATTSTASSASKRNP-- 3375
                              :|...::|..|.:..:.......|:|........|..|::....|
 Frog  2988 SSSTLKTNSITDSTCEDNAEVKSVDDGSSKVHFSIGKAPLKEEQDTRASPKISRKSTSRHVRPKK 3052

  Fly  3376 --------------MGPIKRAMPPSFAESIRAVFAALLWHEGVVHDAMACASFLKFHPGLPKEGA 3426
                          :.|.|.||.||.||..||||||.|||||:|||||||:|||||:|.|.||.|
 Frog  3053 EKSNFFFKGESSKSIEPAKEAMSPSVAECARAVFAAFLWHEGIVHDAMACSSFLKFNPDLSKEHA 3117

  Fly  3427 TVVTRRGESGDPRLQLSREQKAQQRHSVEVANAGNYLNIRP-----STLETLTKSGNCS------ 3480
            .:   |....:.:....:|.|.:.|||:|:::|.|..:|.|     |.:.::.|:...|
 Frog  3118 PI---RCSLNNQQPSEEKEVKLKNRHSIEISSALNMFHIAPHGPDISKMGSINKNKVLSMLKEPP 3179

  Fly  3481 LHNRSKYRKNLLSGGGGAINSGDDTAQKLQA--LPEMVSV-----LPPALRCLVYLWEQICSGCV 3538
            ||  .||               :|...:..|  ||...||     ||..|:.||..||.|....:
 Frog  3180 LH--EKY---------------EDGKHETSAFDLPSQHSVKTKSPLPLTLQHLVAFWEDISLATI 3227

  Fly  3539 QIVQSNALEQREPRLLSPGS----RDLNGDADTE--GKEGKNSDQASAGEKD--LGRKCK----R 3591
            :....|.:      ..||||    :..:||.|.:  .||.|..::|.:..:.  .|...:    .
 Frog  3228 KAASQNMI------FPSPGSCAVLKKKDGDKDNKKAKKEKKKKEKAESRPRGNLFGEMAQLAVGG 3286

  Fly  3592 KKKDDGSWCEICELFLPMPVTYHMRIAHPGCGKSAKGKGYNSVGIFCEGWAGNCGEGGKGASSWF 3656
            .:||  :.||:|....|.|||||||.||||||:.|.|:||||:|.||.|||||||:||.|.|:|:
 Frog  3287 PEKD--TICELCGESHPYPVTYHMRQAHPGCGRYAGGQGYNSIGHFCGGWAGNCGDGGIGGSTWY 3349

  Fly  3657 LMCDPCRDRYLASCRSANNINSAARQLESSAAEGNELNLFGVKSTTLIANAEVYTTMRENATFLL 3721
            |:||.||::||...:.|  :....:|......:        ||:...:...|.:..::.||.|||
 Frog  3350 LVCDRCREKYLREKQVA--VREKVKQSRRKPVQ--------VKTPRALPTMEAHQVIKANALFLL 3404

  Fly  3722 ELCSSSSSASGAAGSLAATSSSSKRSPQQMSVVAMPVVIEHQLGNSDLKPSTSRC---SRMARLS 3783
            .|.|            ||..:.....|.:..:..:|.|.|  ..:.|:.|. .:|   ..:||..
 Frog  3405 SLSS------------AAEPNILCYHPPKPFLSHLPSVKE--TISEDIPPK-MQCLYLQTLARHH 3454

  Fly  3784 GSKFCPGVGSGAFRKSFVGGPPTAPENVWLAPESFACLECLGTAGHEDLPYEMFGLGPNSNDNGY 3848
            ...|........|:          .|..:|...|              :|.....:.|::..|.:
 Frog  3455 HDNFVGYQDDNLFQ----------DEMRYLRSTS--------------VPAPYISVTPDACPNVF 3495

  Fly  3849 DRPLSEISYESCEPNNYDMLSGSLAPGTTAAASVGGGNLSKFHRSYSMGQGWASLAQHNHPPPHH 3913
            :.|          .||...:..||.  |:..........:.|.||||:
 Frog  3496 EEP----------ENNMKSMPPSLE--TSPITDTDSAKRTVFQRSYSV----------------- 3531

  Fly  3914 PQQQHHQQQQMNLQLQQHQAPPVDGQPKVVYRRRNNSTSEGDGSLLICYPSEHLRRLVPQKLLAS 3978
             ....:.:|...||      |.|    |.:.|||.||.....||.|:.:||..|.||:
 Frog  3532 -VASEYDKQHSILQ------PRV----KAIPRRRVNSGDAEVGSSLLRHPSPELSRLI------- 3578

  Fly  3979 VSVMQTASGEGTGKDHATGTLGLDQSAGQNGGGNLLLTRPAMAFITQKHELDRLRAAMRRSLRIA 4043
                         ..|::      .|.|:..     ...|.:||:.|.|:|:.|..||:::||.:
 Frog  3579 -------------SAHSS------LSKGERN-----FQWPVLAFVIQHHDLEGLEIAMKQALRKS 3619

  Fly  4044 ACRIYALQALNWLLRSVTQGVCLHDLMWWFVSSLNPTGGHQPVERGEEASEP------------- 4095
            |||::|::|.||||.:|.|...|||::|.||:||.|.    |||..|:..|.
 Frog  3620 ACRVFAMEAFNWLLCNVIQTTSLHDILWHFVASLTPA----PVEPEEDEDEENKANKENAEQEKD 3680

  Fly  4096 --ALEHPVAYTQISGRFAHLITQSLHVFLQSVADLTLHLPLGSPLQRVAIQCFGIRFRQADHQFL 4158
              ..|||::...|:|..||.:..:.|..||:::||.:.||.||.||::|::|:.::|:|:|||||
 Frog  3681 TRVCEHPLSDIVIAGEAAHPLPDTFHRLLQTISDLMMSLPGGSSLQQMALRCWSLKFKQSDHQFL 3745

  Fly  4159 HSSHVFGNISKILSKSDEQNDAMAVSTILKPDCDVEHNQVHSVATG--GSSGAGARLLCYT---- 4217
            |.|:||.:|:.||||||              |.|.|.:...||.:|  ||        |..
 Frog  3746 HQSNVFRHINNILSKSD--------------DGDSEESFNISVQSGFEGS--------CLVTGLK 3788

  Fly  4218 DLAGMFEVTVSSRPAMAESLTDNSTETFWESDEEDRNKCKIIELSLTK-LNYACRYLLVHIDNSR 4281
            |:..:.::..||||||..||||.||||||||.:||:||.|.|.::..| :|  .||:.|||||||
 Frog  3789 DMTSIVDIKTSSRPAMIGSLTDGSTETFWESGDEDKNKTKSITINCVKGIN--TRYVSVHIDNSR 3851

  Fly  4282 DIQNKVLNVVFYAGQSLGDTNIIKSADVDPKACSWISAKICDDSCTHFRLELHGPENTLRVRQIK 4346
            |:.|||.::.|.:|:::.|...||.||:|.:...|:::::........::||.||||||||||:|
 Frog  3852 DLGNKVTSLTFLSGKTVEDLCRIKQADLDSRHIGWVTSELPGGDNNIIKIELKGPENTLRVRQVK 3916

  Fly  4347 LLG------LPIGGAVGSDDSSDHKHQPHLRLSHASRIQQQICEAETLRVFRLITGQVFGKLISN 4405
            :||      :.|.|.:.                 ||..||:.||:||||||||||.|||||||
 Frog  3917 VLGWKDGETIKIPGQIS-----------------ASVAQQRNCESETLRVFRLITSQVFGKLI-- 3962

  Fly  4406 VSSDLVP----PDSAGIGPPSGGAASTSLLADSLDLREHMVGILFSRSKLSHLQKQVIVHIVHAI 4466
             |.|..|    .:...:..|.|...:.|    ..||:||||||:||||||::|||||..|||.||
 Frog  3963 -SGDAEPTPEQEEKTLLSSPEGEEKAPS----DADLKEHMVGIIFSRSKLTNLQKQVCAHIVQAI 4022

  Fly  4467 RKEAQRAKEDWELANLAHVLKQSPQQQTAPALAASASCESTP-ERSRAPDTYCFEMLSMVLALSG 4530
            |.||.|.:|:||     |            |:::..:..|.| :...:.|.||||:|||||||||
 Frog  4023 RMEAMRVREEWE-----H------------AISSKENANSQPNDEDASSDAYCFELLSMVLALSG 4070

  Fly  4531 SVVGRSYLSQQHGLLRDLLGLLHTGSDRVQRQVTALLRRILPEITPESFAELLGVQRLPPADYSI 4595
            |.|||.||:||..||:||..||||.|.|||||||:||||:|||:||...|.::||:.|||||.|.
 Frog  4071 SNVGRQYLAQQLTLLQDLFHLLHTASPRVQRQVTSLLRRVLPEVTPSRLASIIGVKSLPPADISD 4135

  Fly  4596 AHQSASDFDMSRLGLLDIFLAVIAKSLQLQVKVKTTVASTGPSGSGGVSGSSSGNGGAVLKAGQQ 4660
            ...|....|.:::|:||:||..|||:|.:|:|.|.|...       |.:|:|:|.|...:
 Frog  4136 IIHSTEKGDWNKMGILDMFLGCIAKALTVQLKAKGTPIK-------GTAGTSAGKGVTTV----- 4188

  Fly  4661 EKTPAFVRLWSSLDLSVQQLRSRPPTGEPGTTDPFQFDALPPRK-ESKRNLNQRWFLNGVISTKQ 4724
                                           |.|..|::...|: ||      .|::.|...|:.
 Frog  4189 -------------------------------TLPMIFNSSYLRRGES------HWWMKGSTPTQI 4216

  Fly  4725 AESIISLIRDLASGKLSEKWSQITKAAIAESVLNLTRLEEIYRSPEHCTKTSTLWLALASLCVLE 4789
            :|.||.||:|:|:|.|||.||::||.||||:::.||::||.||||..|..|:.||||:||||||:
 Frog  4217 SEIIIKLIKDMAAGHLSEAWSRVTKNAIAETIIALTKMEEEYRSPVRCIATTRLWLAVASLCVLD 4281

  Fly  4790 RDHVEKLSSGQWSKLCDTR---PLCSNHDDGETAAIIQCETCGSLCGDCDRFLHLNRKTRSHKRT 4851
            :|||::||||:|......:   |:|.|||||||||||.|..||:||.||||||||:|:|:||:|.
 Frog  4282 QDHVDRLSSGRWMGKDGQQKQMPMCDNHDDGETAAIILCNACGNLCTDCDRFLHLHRRTKSHQRQ 4346

  Fly  4852 VCKEEEEAIRVELHESCGRTKLFWLLALADSKTLKAMVEFRDGSHTIISGPQEAVGRCRFCGLTG 4916
            |.|||||||:|:|||.|||||||||:|||||||:|||||||:.:....|...|.   |||||...
 Frog  4347 VFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREQTGKPASSSSET---CRFCGSRN 4408

  Fly  4917 NSGLLEIGNVCADAQCQEYAANSCLKTKPCGHACGGVTGERKCLPCLQHVCHTRENELAEELRDP 4981
            .:.|..:|:||:|:.|||||..:|.||..|||.||||..|..||||| |.|         :....
 Frog  4409 GTELSAVGSVCSDSDCQEYAKTACSKTHSCGHPCGGVKNEDHCLPCL-HGC---------DKNAT 4463

  Fly  4982 KLTQDADDMCMICFVEALSCAPSIHLECGHVFHYHCCKAVLEKRWSGPRITFGFSLCPICKADIQ 5046
            .|.|||||||||||.||||.||:|.|:|.||||..||:.|||.||.||||||||..|||||..|.
 Frog  4464 SLKQDADDMCMICFTEALSAAPAIQLDCSHVFHMQCCRRVLENRWLGPRITFGFMSCPICKNKIN 4528

  Fly  5047 HPLLSDILEPINGLKQDVKRKALMRIKYEGVVKDTDSKNV-------NMTQLAMDRYAYYVCFKC 5104
            |.:|.|:|:||..|.:||:||||||::|||:.| :|:...       :....||:|||||||:||
 Frog  4529 HTVLKDLLDPIKELYEDVRRKALMRLEYEGLHK-SDAITTPGVRFYNDPASYAMNRYAYYVCYKC 4592

  Fly  5105 QKAYYGGEARCDAEI--GEKFDPEELVCGGCSDVARAQMCPKHGTDFLEYKCRYCCSVAVFFCFG 5167
            :|||:|||||||||.  |:.:||.||:||.||||:||||||||||||||||||||||||||||||
 Frog  4593 KKAYFGGEARCDAEAGQGDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFG 4657

  Fly  5168 TTHFCDTCHDDFQRLTNIPKVKLPQCPAGPKAKQLLGDECPLHVMHPPTGEEFALGCGVCRNAQT 5232
            |||||:.|||||||:|::||.:||.||||||.|||.|.||||||:||||||||||||||||||.|
 Frog  4658 TTHFCNACHDDFQRMTSLPKEELPHCPAGPKGKQLEGTECPLHVVHPPTGEEFALGCGVCRNAHT 4722

  Fly  5233 F 5233
            |
 Frog  4723 F 4723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hiw	NP_001285258.1	RCC1_2	752..781	CDD:290274	16/28 (57%)
		RCC1_2	968..997	CDD:290274	16/28 (57%)
		RCC1	985..1031	CDD:278826	25/46 (54%)
		RCC1_2	1018..1047	CDD:290274	15/28 (54%)
		PHR	1437..1585	CDD:285277	94/147 (64%)
		PHR	2015..2167	CDD:285277	68/154 (44%)
		zf-RING_2	4989..5042	CDD:290367	38/52 (73%)
mycbp2	XP_031752927.1	RING-H2_PHR	4470..4524	CDD:319377	39/53 (74%)
		ATS1	<456..650	CDD:227511	101/205 (49%)
		ATS1	597..969	CDD:227511	126/383 (33%)
		RCC1	903..951	CDD:395335	25/47 (53%)
		PHR	1180..1330	CDD:400388	96/149 (64%)
		PHR	1671..1828	CDD:400388	69/156 (44%)
		Filamin	<2336..2387	CDD:421532	20/50 (40%)
		SH3_3	2419..2470	CDD:400512	32/50 (64%)
		Bbox2_MYCBP2	4304..4352	CDD:380857	34/47 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	308	1.000	Domainoid score	I1338
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	2956	1.000	Inparanoid score	I19
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D117289at33208
OrthoFinder	1	1.000	-	-		FOG0005457
OrthoInspector	1	1.000	-	-		oto104189
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4751
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060