DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eag and GORK

DIOPT Version :9

Sequence 1:	NP_001036275.1	Gene:	eag / 32428	FlyBaseID:	FBgn0000535	Length:	1270	Species:	Drosophila melanogaster
Sequence 2:	NP_001332118.1	Gene:	GORK / 833728	AraportID:	AT5G37500	Length:	842	Species:	Arabidopsis thaliana

Alignment Length:	837	Identity:	175/837 - (20%)
Similarity:	300/837 - (35%)	Gaps:	231/837 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 FKAIWDWVILCLTFYTAIMVPYNVAFKNKTSEDVSLLVVDSIVDVIFFIDIVLNFHTTFVGPGG- 298
            :|| |:..||....|:::..|....|.....|  .|.|:|.:..:.|.:||||.|...:.....
plant    65 YKA-WEMFILVWAIYSSLFTPMEFGFFRGLPE--RLFVLDIVGQIAFLVDIVLQFFVAYRDTQTY 126

  Fly   299 EVVSDPKVIRMNYLKSWFIIDLLSCLPYD-VFNAFDRDEDGIGSLFSALKVVRLLRLGRVVR--- 359
            ..|..|..|...||||.|::|.:.|.|:| ::.|..:.|     |...|..:||.|:.:||.
plant   127 RTVYKPTRIAFRYLKSHFLMDFIGCFPWDLIYKASGKHE-----LVRYLLWIRLFRVRKVVEFFQ 186

  Fly   360 --KLDRYLEYGAAMLILLLCFYMLVAHWLACIWYSIGRSDADNGIQYSWLWKLANVTQSPYSY-- 420
              :.|..:.|....::.||...:...|..|||:|.:..:.......|:|   :.::....|||
plant   187 RLEKDTRINYLFTRILKLLFVEVYCTHTAACIFYYLATTLPPENEGYTW---IGSLKLGDYSYEN 248

  Fly   421 -----IWSNDTGPELVNGPSRKSMYVTALYFTMTCMTSVGFGNVAAETDNEKVFTICMMIIAALL 480
                 :|..               |.|||||.:..|.:||:|::.|....|.:|.:..:....:|
plant   249 FREIDLWKR---------------YTTALYFAIVTMATVGYGDIHAVNLREMIFVMIYVSFDMVL 298

  Fly   481 YATIFGHVTTIIQQMTSATAKYHDMLNNVREFMKLHEVPKALSERVMDYVVSTWAMTKGLDTEKV 545
            .|.:.|::|.:|.: .|.|.::.|.:|::..||...::.:.|..::..:|...:. :...|| .:
plant   299 GAYLIGNITALIVK-GSNTERFRDKMNDLISFMNRKKLGRDLRSQITGHVRLQYD-SHYTDT-VM 360

  Fly   546 LNYCPKDMKADICVHLNRKVFNEHPAFRLASDGCLRALAMHFMMSHSAPGDLLYHTGESIDSLCF 610
            |...|..::|.|...|......:.|.|:..|...:..:.:.....:..||:::...|..:|.|.|
plant   361 LQDIPASIRAKIAQLLYLPYIKKVPLFKGCSTEFINQIVIRLHEEYFLPGEVITEQGNVVDHLYF 425

  Fly   611 IVTGSLEVI-----QDDEVVAILGKGDVFGD---------QFWKDSAVGQSAANVRALTYCDLHA 661
            :..|.||.:     ..:|.|.:||....|||         .|           .||....|.|..
plant   426 VCEGLLEALVTKTDGSEESVTLLGPHTSFGDISIICNISQPF-----------TVRVCELCHLLR 479

  Fly   662 IKRDKLLEVLDFYSAFANSFARNLVLTYNLRHRLIFRKV-ADV-----KREKELAERRKNEP--- 717
            :.:.....:|:.|.....:...|::.......|:  :|: :|:     |:|.|||.:..:..
plant   480 LDKQSFSNILEIYFHDGRTILNNIMEEKESNDRI--KKLESDIVIHIGKQEAELALKVNSAAFQG 542

  Fly   718 ---QL---------PQNQDH-----LVR------------------------------------- 728
               ||         |...|:     |||
plant   543 DFYQLKSLIRSGADPNKTDYDGRSPLVRLSLIDYLSFKSLTLILFYIQHLAACRGYEDITLFLIQ 607

  Fly   729 -----KIFSKFRRTP---QVQAGSKELVG------------GSGQ---SDVEKGDGEVERTKLPA 770
                 .:..||..||   .|:||.:.::|            .||.   :.|.|||.:..:
plant   608 EGVDVNLKDKFGHTPLFEAVKAGQEGVIGLLVKEGASFNLEDSGNFLCTTVAKGDSDFLK----- 667

  Fly   771 KLTLTEDARILSTAAAPSPSP----SP---SPSSG---------PPSARSTRASKWG-------R 812
                    |:||:...|:...    :|   :.|.|         ...|......:||       |
plant   668 --------RLLSSGMNPNSEDYDHRTPLHVAASEGLFLMAKMLVEAGASVISKDRWGNSPLDEAR 724

  Fly   813 LLGSSSVDSASDTSAKVAVSRSLSARESLRESTAQARQSSTSSSNGGQGNKVFPKAPKLQASQAT 877
            |.|:..:....:.......|...|:...|:|...:.|:.:           |||..|:
plant   725 LCGNKKLIKLLEDVKNAQSSIYPSSLRELQEERIERRKCT-----------VFPFHPQ------- 771

  Fly   878 LARQDTIDEGGEVDSSPPSRDSRVVIEGAAVSSATVGPSPPVATTSSAAAGAGVSGG 934
            .|:::...:.|.|...|.:.:..:|                     :||...|:|.|
plant   772 EAKEERSRKHGVVVWIPSNLEKLIV---------------------TAAKELGLSDG 807

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eag	NP_001036275.1	PAS_9	28..155	CDD:290162
		PAS	40..153	CDD:238075
		Ion_trans	254..499	CDD:278921	67/258 (26%)
		Ion_trans_2	<440..494	CDD:285168	18/53 (34%)
		Crp	565..>702	CDD:223736	29/151 (19%)
		CAP_ED	571..682	CDD:237999	25/124 (20%)
GORK	NP_001332118.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	111	1.000	Domainoid score	I2073
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000148
OrthoInspector	1	1.000	-	-		mtm987
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X71
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910