DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eag and KT2/3

DIOPT Version :9

Sequence 1:	NP_001036275.1	Gene:	eag / 32428	FlyBaseID:	FBgn0000535	Length:	1270	Species:	Drosophila melanogaster
Sequence 2:	NP_567651.1	Gene:	KT2/3 / 828311	AraportID:	AT4G22200	Length:	802	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	128/563 - (22%)
Similarity:	249/563 - (44%)	Gaps:	66/563 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 RQFSAHLPTLKDPTKQSNLAHMMSLSADIMP-----QYRQEAPKTPPHILLHYCAFKAIWDWVIL 244
            |:|..|....::....::...:.:||..|:|     .|.|...::...|:....:....|::.::
plant    19 RRFHQHRGKGREEEYDASSLSLNNLSKLILPPLGVASYNQNHIRSSGWIISPMDSRYRCWEFYMV 83

  Fly   245 CLTFYTAIMVPYNVAFKNKTSEDVSLLVVDSIVDVIFFIDIVLNFHTTFVGPGGE-VVSDPKVIR 308
            .|..|:|.:.|:.|||.| :|...:|.:.|:|||:.|.:||||.|...::....: :|.:||.|.
plant    84 LLVAYSAWVYPFEVAFLN-SSPKRNLCIADNIVDLFFAVDIVLTFFVAYIDERTQLLVREPKQIA 147

  Fly   309 MNYLKSWFIIDLLSCLPYDVFNAFDRDEDGIG---SLFSALKVVRLLRLGRVVRKLDRYLEYGAA 370
            :.||.:||::|:.|.:|:|...........:.   :|...|:..||.|:..:..:|::.:.|.
plant   148 VRYLSTWFLMDVASTIPFDAIGYLITGTSTLNITCNLLGLLRFWRLRRVKHLFTRLEKDIRYS-- 210

  Fly   371 MLILLLCFYML-----VAHWLACIWYSIGRSDADNGIQYSWLWKLANVTQSPYSYIWSNDTGPEL 430
             ...:.||.:|     :.|...|.:|.|.......|  .:|...:.|.|::..|.
plant   211 -YFWIRCFRLLSVTLFLVHCAGCSYYLIADRYPHQG--KTWTDAIPNFTETSLSI---------- 262

  Fly   431 VNGPSRKSMYVTALYFTMTCMTSVGFGNVAAETDNEKVFTICMMIIAALLYATIFGHVTTIIQQM 495
                    .|:.|:|:::|.||:||:|::.|....|.||....|:....|.|.:.|::|.::.:.
plant   263 --------RYIAAIYWSITTMTTVGYGDLHASNTIEMVFITVYMLFNLGLTAYLIGNMTNLVVEG 319

  Fly   496 TSATAKYHDMLNNVREFMKLHEVPKALSERVMDYVVSTWAMTKGLDTEKVLNYCPKDMKADICVH 560
            |..|.::.:.:.....|:..:.:|..|.::::.|:...: ..:.|:.:.:::..||.:...||.|
plant   320 TRRTMEFRNSIEAASNFVNRNRLPPRLKDQILAYMCLRF-KAESLNQQHLIDQLPKSIYKSICQH 383

  Fly   561 LNRKVFNEHPAFRLASDGCLRALAMHFMMSHSAPGDLLYHTGESIDSLCFIVTGSLEVIQDD-EV 624
            |......:...|:..|...|..|.......:..|.:.:....|:.|.:..||:|.:|:|..: |.
plant   384 LFLPSVEKVYLFKGVSREILLLLVSKMKAEYIPPREDVIMQNEAPDDVYIIVSGEVEIIDSEMER 448

  Fly   625 VAILGK---GDVFGDQFWKDSAVGQSAANVRALTY-----CDLHAIKRDKLLEVLDFYSAFANSF 681
            .::||.   ||:||:       ||......::.|:     ..|..:|...|:|.:........:.
plant   449 ESVLGTLRCGDIFGE-------VGALCCRPQSYTFQTKSLSQLLRLKTSFLIETMQIKQQDNATM 506

  Fly   682 ARNLVLTYNLRH--RLIFRKVADVKREKELAERRKNEPQLPQN 722
            .:|.     |:|  :|....:.|:|.:    :..:|...:|.|
plant   507 LKNF-----LQHHKKLSNLDIGDLKAQ----QNGENTDVVPPN 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eag	NP_001036275.1	PAS_9	28..155	CDD:290162
		PAS	40..153	CDD:238075
		Ion_trans	254..499	CDD:278921	67/253 (26%)
		Ion_trans_2	<440..494	CDD:285168	18/53 (34%)
		Crp	565..>702	CDD:223736	30/147 (20%)
		CAP_ED	571..682	CDD:237999	26/119 (22%)
KT2/3	NP_567651.1	PLN03192	23..802	CDD:215625	126/559 (23%)
		ANK repeat	574..604	CDD:293786
		ANK repeat	606..668	CDD:293786
		ANK repeat	670..695	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	111	1.000	Domainoid score	I2073
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm987
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X71
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910