DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eag and KAT2

DIOPT Version :9

Sequence 1:	NP_001036275.1	Gene:	eag / 32428	FlyBaseID:	FBgn0000535	Length:	1270	Species:	Drosophila melanogaster
Sequence 2:	NP_001329801.1	Gene:	KAT2 / 827555	AraportID:	AT4G18290	Length:	708	Species:	Arabidopsis thaliana

Alignment Length:	460	Identity:	117/460 - (25%)
Similarity:	209/460 - (45%)	Gaps:	66/460 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 HMMSLSADIMPQYR---QEAPKTPPHILLHYCAFKAIWDWVILCLTFYTAIMVPYNVAFKNKTSE 266
            |...||||::|...   .::.|...||:..:......|:..::.|..|:|.:.|:..||  .|.:
plant    36 HSSFLSADLLPSLGARINQSTKLRKHIISPFDPRFRGWEMWLVILVIYSAWICPFEFAF--ITYK 98

  Fly   267 DVSLLVVDSIVDVIFFIDIVLNFHTTFVGPGGEVVSD-PKVIRMNYLKSWFIIDLLSCLPYDVFN 330
            ..:|.::|:||:..|.|||:|.|...::.....::.| ||.|.:.||.:||..|:.|..|:...:
plant    99 KDALFIIDNIVNGFFAIDIILTFFVAYLDSHSYLLVDKPKKIAIRYLSTWFAFDVCSTAPFQSLS 163

  Fly   331 -AFDRDEDGIGSLFSALKVVRLLRLGRV---VRKLDRYLEYG-----AAMLILLLCFYMLVAHWL 386
             .|..:...||  |..|.::||.||.||   ..:|::.:.:.     ...||.:..|   ..|..
plant   164 LLFKYNGSEIG--FRVLSMLRLWRLRRVSSLFARLEKDIRFNYFWTRCTKLISVTLF---AVHCA 223

  Fly   387 ACIWYSIGRSDADNGIQYSWLWKLANVTQSPYSYIWSNDTGPELVNGPSRKSMYVTALYFTMTCM 451
            .|..|.|    ||.....:..|..|.......:.:||.               ||||||:::|.:
plant   224 GCFAYLI----ADQYHDPTKTWIGAVYPNFKETSVWSR---------------YVTALYWSITTL 269

  Fly   452 TSVGFGNVAAETDNEKVFTICMMIIAALLYATIFGHVTTIIQQMTSATAKYHDMLNNVREFMKLH 516
            |:.|:|::.||...|.:|.:..|:......:.:.|::|.::...||.|..:.|.:....||...:
plant   270 TTTGYGDLHAENPREMLFFVFFMLFNLGFTSYLIGNMTNLVVHWTSRTRNFRDTVRAASEFASRN 334

  Fly   517 EVPKALSERVMDYVVSTWAMTKGLDTEKVLNYCPKDMKADICVHL------NRKVF---NEHPAF 572
            ::|..:.::::.::...: .|:||..::.||..||.:::.|..:|      |..:|   :.:..|
plant   335 QLPPNIQDQMLSHICLKF-KTEGLKQQEALNGLPKAIRSSIANYLFFPIVQNVYLFHGVSRNFLF 398

  Fly   573 RLASDGCLRALAMHF------MMSHSAPGDLLYHTGESIDSLCFIVTGSLEVIQDDEVVAILGKG 631
            :|.||    ..|.:|      ::.:.||.||......::|...::  |..:.:|...||     |
plant   399 QLVSD----IDAEYFPPREDVILQNEAPTDLYILVSGAVDFTVYV--GEEDQVQGKAVV-----G 452

  Fly   632 DVFGD 636
            |.||:
plant   453 DAFGE 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eag	NP_001036275.1	PAS_9	28..155	CDD:290162
		PAS	40..153	CDD:238075
		Ion_trans	254..499	CDD:278921	69/254 (27%)
		Ion_trans_2	<440..494	CDD:285168	17/53 (32%)
		Crp	565..>702	CDD:223736	20/81 (25%)
		CAP_ED	571..682	CDD:237999	19/72 (26%)
KAT2	NP_001329801.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	111	1.000	Domainoid score	I2073
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm987
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X71
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910