Protein Alignment eag and cng-2

DIOPT Version :9

• Sequence 1: NP_001036275.1
• Gene: eag / 32428
• FlyBaseID: FBgn0000535
• Length: 1270
• Species: Drosophila melanogaster
• Sequence 2: NP_001343690.1
• Gene: cng-2 / 190732
• WormBaseID: WBGene00022295
• Length: 819
• Species: Caenorhabditis elegans
• Alignment Length: 646
• Identity: 140/646 - (21%)
• Similarity: 252/646 - (39%)
• Gaps: 131/646 - (20%)

  Fly   169 LGLSKFAKLARSVTRSRQFSAHLPTLKDPTKQS-----NLAHMMS--LSA--------------- 211
            |.|:|    :||.:::|:.||.....:||.::|     ..|.|:.  :||
 Worm   117 LDLNK----SRSTSKNRRKSAQNGGAEDPGQKSFSDVVKTAMMLRTWISAMEHDERESEPDRDAT 177

  Fly   212 ------------DIMP-----QYRQEAPKTPPHILLHYCAFKAIWDWVILCLTFY---TAIM--- 253
                        .|:|     |.||........||...|. |..:.:|....||:   |||:
 Worm   178 TTNAEITAADDRSILPSPPIFQQRQTGFTQIKDILTDKCR-KLYYFYVTENSTFFYYWTAIISIG 241

  Fly   254 VPYNV-AFKNKTSEDVSL------LVVDSIVDVIFFIDIVLNFHTTFVGPGGEVVSDPKVIRMNY 311
            :.||: |......:||..      |.|:...|..|.:|.::....|||..|.||....|:.: ||
 Worm   242 ILYNMFAMVIFIFDDVHFGYFNQWLYVNLFFDFCFLLDCLVGSRMTFVSEGNEVSQTDKMFK-NY 305

  Fly   312 LKSWFI-IDLLSCLPYDVFNAFDRDEDGIGSLFSALKVVRLLRLGRVVRKLDRYLEYGAAMLILL 375
            .:|... :|||...|.|.:...|..    .||..|:::|:..||...:....|..::...|.||.
 Worm   306 RQSRRCKLDLLCLAPADFYLFIDTK----ASLVRAIRLVKAYRLYEFIMLTQRRTDFPHFMKILF 366

  Fly   376 L---CFYMLVAHWLACIWYSIG-----RSDADNGIQYSWLWKLANVTQSPYSYIWSND----TGP 428
            |   |  .::.||.||:::...     ..|..|...:|: :|:.:...|....::..|    ...
 Worm   367 LTSSC--AILFHWNACVYFLFSLYQGLTEDDPNAFGFSY-YKVFDPRFSICDALYDQDCYYPEDT 428

  Fly   429 ELVNGPSRKSMYVTALY-FTMTCMTSVGFGNVAAE----------------------TDNEKVFT 470
            |:::....:..|:..:| |.......:..||.:.|                      ..::....
 Worm   429 EVLDIRDERPHYMEDMYKFWDKKFNILQIGNFSREYSMTIYWSSLTITKCGQQPWPSKSSQNSLE 493

  Fly   471 ICMMIIAALLYATIFGHVTTIIQQMTSATAKYHDMLNNVREFMKLHEVPKALSERVMDYVVSTWA 535
            |...:|..|::|||.|.|.:::.||:.....:.:|::.::.:||...|..|:.:||::..:...:
 Worm   494 IFDTLIGVLVFATIIGGVGSVVTQMSQNVNDFREMMDGIKFYMKYRGVQSAIQDRVLNCFLYLNS 558

  Fly   536 MTKGLDTEKVLNYCPKDMKADICVHLNRKVFNEHPAFRLASDGCLRALAMHFMMSHSAPGDLLYH 600
            ..:..|.|::|:..|...:|.|..:|::...::...|.......|:.:.|.......:|.|.|..
 Worm   559 HNQLYDEEEILSLLPPFFQARIAANLHQDTLSKVSLFYKCDQRLLQEVVMLVKQQVYSPNDYLCR 623

  Fly   601 TGESIDSLCFIVTGSLEVIQDD---------------EVVAILGKGDVFGDQFWKDSAVGQSAAN 650
            ..|....:..:..|.|.||.||               |:..:..||::.||         :.:.:
 Worm   624 KNEKAKEMFIVKKGLLAVIDDDTGVELDSLKEGHTFGELSIVQVKGNILGD---------RRSVS 679

  Fly   651 VRALTYCDLHAIKRDKLLEVLDFYSAFANSFARNLVLTYNLRHRLIFRKVADVKREKELAE 711
            :|::.|.|::.:.:|.:..:|..|.      ...:.|..|.|..|..|.:.:.....|:.|
 Worm   680 LRSVGYSDVYVLHQDDVTRLLQEYP------EERVRLMENARRMLHSRGLLETNELGEMCE 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eag	NP_001036275.1	PAS_9	28..155	CDD:290162
		PAS	40..153	CDD:238075
		Ion_trans	254..499	CDD:278921	65/287 (23%)
		Ion_trans_2	<440..494	CDD:285168	14/76 (18%)
		Crp	565..>702	CDD:223736	29/151 (19%)
		CAP_ED	571..682	CDD:237999	24/125 (19%)
cng-2	NP_001343690.1	Ion_trans	232..>407	CDD:366146	49/182 (27%)
		PLN03192	<457..>713	CDD:215625	52/270 (19%)
		CAP_ED	594..711	CDD:237999	24/131 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158447
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840