Protein Alignment eag and cnga1a

DIOPT Version :10

• Sequence 1: NP_001036275.1
• Gene: eag / 32428
• FlyBaseID: FBgn0000535
• Length: 1270
• Species: Drosophila melanogaster
• Sequence 2: NP_001139095.1
• Gene: cnga1a / 100001558
• ZFINID: ZDB-GENE-090312-66
• Length: 697
• Species: Danio rerio
• Alignment Length: 600
• Identity: 147/600 - (24%)
• Similarity: 265/600 - (44%)
• Gaps: 89/600 - (14%)

  Fly   218 RQEAPK----TPPHILLHYCAFKAIWDWVILCLTFYTAIMVPYNVAFKNKTSED------VSLLV 272
            ::|.||    ..|..||:|       .| :|.:||  .:|..:.|.......|:      ::..:
Zfish   122 KKEGPKEVFVINPAGLLYY-------QW-LLIITF--PVMYNWTVIIARACFEELQHEYLLTWFL 176

  Fly   273 VDSIVDVIFFIDIVLNFHTTFVGPGGEVVSDPKVIRMNYLKS-WFIIDLLSCLPYDVFNAFDRDE 336
            :|...|:::..|:.....|.:: ..|.:|.|.|::...|..| .|.:|::|.||.|:|...
Zfish   177 LDYTSDLLYLADMAFRARTGYL-EQGLLVKDEKLLLKRYTDSLQFRLDVISMLPTDIFYFI---- 236

  Fly   337 DGIGSLFSALKVVRLLRLGRVVR--KLDRYL-EYGAAMLILLLCFY-MLVAHWLACIWYSIGR-- 395
              :|..:..:::.:||||.|:..  |:...: .|.....|..|..| :::.||.||:::|..:
Zfish   237 --LGLDYPEIRINKLLRLNRMFEFFKISETMTNYPNIFRICTLVMYIIIIIHWNACLYFSFSKSI 299

  Fly   396 ---SDADNGIQYSWLWKLANVTQSPYSYIWSNDTGPELVNGPSRKSMYVTALYFTMTCMTSVGFG 457
               |||         |....:|:..:.         ||:    ||  |..:||::...:|::| .
Zfish   300 GFGSDA---------WVYPALTEPEFG---------ELM----RK--YSFSLYWSTLTLTTIG-E 339

  Fly   458 NVAAETDNEKVFTICMMIIAALLYATIFGHVTTIIQQMTSATAKYHDMLNNVREFMKLHEVPKAL 522
            ..:.|.|:|..|.:...::..|::|||.|::.|:|..|.:|.|::...::|::::|....|.|.|
Zfish   340 TPSPELDSEFFFHVVDFLVGVLIFATIVGNIATMISNMNAAQAQFQARIDNIKQYMHARHVSKEL 404

  Fly   523 SERVMDYVVSTWAMTKGLDTEKVLNYCPKDMKADICVHLNRKVFNEHPAFRLASDGCLRALAMHF 587
            .:||:.:....|...|..|..:||.|.|..::|:|.::::.....:...|.....|.|..|.:..
Zfish   405 EDRVIKWFDYLWTNKKAQDEREVLRYLPDKLRAEIGMNVHLDTLKKVRIFADCEAGLLIELVLKL 469

  Fly   588 MMSHSAPGDLLYHTGESIDSLCFIVTGSLEVIQDDEVV--AILGKGDVFGD----QFWKDSAVGQ 646
            .....:|||.:...|:....:..|..|.|.|:.||.|.  .:||.|..||:    ......|..:
Zfish   470 RPQVFSPGDYICRKGDIGREMYIIKDGKLAVVADDGVTQFVVLGDGSYFGEISILNIKGSKAGNR 534

  Fly   647 SAANVRALTYCDLHAIKRDKLLEVLDFY---SAFANSFARNLVLTYNLRHRLIFRKVADVKREKE 708
            ..||:|::.|.||..:.:|.|:|.|..|   .|......|.::    |:..|:....:.:|.::.
Zfish   535 RTANIRSIGYSDLFCLSKDDLMEALTEYPDAKAMLEEKGRQIL----LKDGLLELDPSKLKPDER 595

  Fly   709 LAERRKNEP----QLPQN-------QDHLVRKIFSKFRRTPQVQAGSKELVGGSGQSDVEKGDGE 762
            ..|.|.|..    ||.|.       |....||  |..||..:::....|:|....:.:.|:.:.|
Zfish   596 DLEDRVNRMYSTLQLMQTKVNKLLAQQEETRK--SIRRRIIEIERFVGEVVEDEEEEEKEETEAE 658

  Fly   763 VERTKLPAKLTLTED 777
             ::.:.|.|..:.|:
Zfish   659 -KKEEEPEKERIEEE 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eag	NP_001036275.1	PAS_9	40..155	CDD:463873
		Ion_trans	238..499	CDD:459842	66/276 (24%)
		CAP_ED	571..682	CDD:237999	33/119 (28%)
cnga1a	NP_001139095.1	Ion_trans	139..381	CDD:459842	67/283 (24%)
		CAP_ED	453..569	CDD:237999	33/115 (29%)
		CLZ	569..627	CDD:465160	11/61 (18%)