Protein Alignment pdgy and LYS2

DIOPT Version :9

• Sequence 1: NP_001188590.1
• Gene: pdgy / 32426
• FlyBaseID: FBgn0027601
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_009673.1
• Gene: LYS2 / 852412
• SGDID: S000000319
• Length: 1392
• Species: Saccharomyces cerevisiae
• Alignment Length: 636
• Identity: 133/636 - (20%)
• Similarity: 229/636 - (36%)
• Gaps: 149/636 - (23%)

  Fly    71 TIPNVPLHEYVWRDF------------KKWERRTAAVCVI--------TDRQYTFAQMRDASAAF 115
            ::|: |.....|.||            :.:..||   ||:        ..|.:|:..:...|...
Yeast   222 SLPD-PTKNLGWCDFVGCIHDIFQDNAEAFPERT---CVVETPTLNSDKSRSFTYRDINRTSNIV 282

  Fly   116 AVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLV 180
            |..| .|..:::.||:.|......:..:..:|.::||.|.:.::|.|.|   |||..:.|    |
Yeast   283 AHYL-IKTGIKRGDVVMIYSSRGVDLMVCVMGVLKAGATFSVIDPAYPP---ARQTIYLG----V 339

  Fly   181 GTVSGFATLSQASKL-------VGRQIPIAVVRTSAEEALPEGAIDFSELTSTQNV-----RYED 233
            ....|...:..|.:|       :..::.| |.|.::......|.|:..:|.:.::|     .|:|
Yeast   340 AKPRGLIVIRAAGQLDQLVEDYINDELEI-VSRINSIAIQENGTIEGGKLDNGEDVLAPYDHYKD 403

  Fly   234 LKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTLPGV----- 293
            .:.......|....|.|:||:.|:||||:..|.::......:.....|........|.|:
Yeast   404 TRTGVVVGPDSNPTLSFTSGSEGIPKGVLGRHFSLAYYFNWMSKRFNLTENDKFTMLSGIAHDPI 468

  Fly   294 -----LPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHP 353
                 .|.|....|.|.....:|...|||..           :.||..::.:|.|.:...:
Yeast   469 QRDMFTPLFLGAQLYVPTQDDIGTPGRLAEW-----------MSKYGCTVTHLTPAMGQLL---- 518

  Fly   354 KLTQETAPHLKVVMSGAAPIG----QHDVERFLNKFPNTVFKQGYGMTEASPVVLL------TPE 408
             ..|.|.|..|  :..|..:|    :.|..|......|......||.||....|..      ..:
Yeast   519 -TAQATTPFPK--LHHAFFVGDILTKRDCLRLQTLAENCRIVNMYGTTETQRAVSYFEVKSKNDD 580

  Fly   409 GNKVYASTGVLPASTEAKIVPL------DGSDAKGVGPRTTGELCVRGPQVMAGYLNNDEANQVT 467
            .|.:.....|:||......|.|      |.:...|:|  ..||:.||...:..||....|.|:..
Yeast   581 PNFLKKLKDVMPAGKGMLNVQLLVVNRNDRTQICGIG--EIGEIYVRAGGLAEGYRGLPELNKEK 643

  Fly   468 FYPGNWL-----------------------------RSGDVAFYDEDGLFYITDRMKELIKVKGF 503
            |. .||.                             |:||:..|..:|......|..:.:|::||
Yeast   644 FV-NNWFVEKDHWNYLDKDNGEPWRQFWLGPRDRLYRTGDLGRYLPNGDCECCGRADDQVKIRGF 707

  Fly   504 QVPPAELEAVLRDHPKILE--------------AAVFGIPH--------EFNGEAPR-----AIV 541
            ::...|::..:..||.:.|              ...|.:|.        :|..:.|:     .||
Yeast   708 RIELGEIDTHISQHPLVRENITLVRKNADNEPTLITFMVPRFDKPDDLSKFQSDVPKEVETDPIV 772

  Fly   542 VLRQGEKASAEEISAYVAERVAHYKKLEGGVIFVDEVPKNPTGKILRRELK 592
            ....|....:::|..::.:|:|.| .:...::.:|::|.||.||:.:.:|:
Yeast   773 KGLIGYHLLSKDIRTFLKKRLASY-AMPSLIVVMDKLPLNPNGKVDKPKLQ 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	131/630 (21%)
		Firefly_Luc_like	99..587	CDD:213279	123/581 (21%)
LYS2	NP_009673.1	alpha_am_amid	7..1379	CDD:274582	133/636 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910