DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdgy and FAT1

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_009597.2	Gene:	FAT1 / 852329	SGDID:	S000000245	Length:	669	Species:	Saccharomyces cerevisiae

Alignment Length:	542	Identity:	126/542 - (23%)
Similarity:	210/542 - (38%)	Gaps:	105/542 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 LQTKFNLQKPDVLAICLPNLPEY-----PIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAK- 177
            |...:|:|..|.:||...|.|.:     .:..:|||.|.|...|..   ||  :...|..|...
Yeast   128 LHFDYNVQAGDYVAIDCTNKPLFVFLWLSLWNIGAIPAFLNYNTKG---TP--LVHSLKISNITQ 187

  Fly   178 -FLVGTVSGFATLSQASKLVGRQIPIAVVRTSAEE---ALPEGAIDF-------SELTSTQN--- 228
             |:....|.               ||   |.|.||   |||:..:::       .||.::|:
Yeast   188 VFIDPDASN---------------PI---RESEEEIKNALPDVKLNYLEEQDLMHELLNSQSPEF 234

  Fly   229 VRYEDLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTLPGV 293
            ::.::::.|...:......|.::||||||||..::|....:..|:.....|.   |..::|:...
Yeast   235 LQQDNVRTPLGLTDFKPSMLIYTSGTTGLPKSAIMSWRKSSVGCQVFGHVLH---MTNESTVFTA 296

  Fly   294 LPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQE 358
            :|.||.....:...:.|..|..||....|....|.:.:.....:.:..|..:..::::.|....|
Yeast   297 MPLFHSTAALLGACAILSHGGCLALSHKFSASTFWKQVYLTGATHIQYVGEVCRYLLHTPISKYE 361

  Fly   359 TAPHLKVVM-SGAAPIGQHDV-ERFLNKFPNTVFKQGYGMTEASPVVLLTPEGN------KVYAS 415
            ....:||.. :|..|    |: :.|..:|...|..:.|..|||........:|:      :.|.:
Yeast   362 KMHKVKVAYGNGLRP----DIWQDFRKRFNIEVIGEFYAATEAPFATTTFQKGDFGIGACRNYGT 422

  Fly   416 TGVLPASTEAKIVPLDGSD-------AKG---VGP-RTTGELCVR-----GPQV-MAGYLNNDEA 463
            ......|.:..:|.:|.:|       :||   |.| ...||:.:|     .|:. ..|||.|.:.
Yeast   423 IIQWFLSFQQTLVRMDPNDDSVIYRNSKGFCEVAPVGEPGEMLMRIFFPKKPETSFQGYLGNAKE 487

  Fly   464 NQV-----TFYPGN-WLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPAELEAVL--RDHPKI 520
            .:.     .|..|: |.|.||:...||.||:|..|||.:..:.|...|...|:|..|  .:..:.
Yeast   488 TKSKVVRDVFRRGDAWYRCGDLLKADEYGLWYFLDRMGDTFRWKSENVSTTEVEDQLTASNKEQY 552

  Fly   521 LEAAVFGIP-HEFNGEAPRAIVVLRQ------------GEKASAEEISAYVAERVAHYKKLEGGV 572
            .:..|.||. .::.|.|..|::.|..            .:..|...:.:|.....         |
Yeast   553 AQVLVVGIKVPKYEGRAGFAVIKLTDNSLDITAKTKLLNDSLSRLNLPSYAMPLF---------V 608

  Fly   573 IFVDEVPKNPTGKILRRELKEK 594
            .||||:......|||::..:|:
Yeast   609 KFVDEIKMTDNHKILKKVYREQ 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	126/542 (23%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	123/533 (23%)
FAT1	NP_009597.2	FATP_chFAT1_like	107..634	CDD:341260	126/542 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910