DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdgy and AAE2

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_177848.1	Gene:	AAE2 / 844060	AraportID:	AT1G77240	Length:	545	Species:	Arabidopsis thaliana

Alignment Length:	544	Identity:	137/544 - (25%)
Similarity:	220/544 - (40%)	Gaps:	89/544 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 TDRQYTFAQMRDASAAFAVRLQT-KFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVY 162
            |...:|:::........|..|.: ...:.:..|:::..||:|...........:|..:..:||..
plant    36 TTTVHTWSETHSRCLRIASTLSSASLGINRGQVVSVIGPNVPSVYELQFAVPMSGAVLNNINPRL 100

  Fly   163 TPDEIARQLTFSGAKFL-VGTVSGFATLSQASKLVGRQIPIAVVRTSAEEALPEGAIDFSELTST 226
            ....::..|..|.:|.: |...|....|...|.|...:.|..|:.....:.....:.|...|.:.
plant   101 DAHALSVLLRHSESKLVFVDHHSSSLVLEAVSFLPKDERPRLVILNDGNDMPSSSSADMDFLDTY 165

  Fly   227 Q------NVRYEDLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNI---TSNCEQVQASLPLD 282
            :      ::|::.::...|.:.   :.|.::||||..||||:.||.::   |.|      || ||
plant   166 EGFMERGDLRFKWVRPKSEWTP---MVLNYTSGTTSSPKGVVHSHRSVFMSTIN------SL-LD 220

  Fly   283 LMGPQNTLPG------VLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNL 341
            .     :||.      .||.||..|.:... :....|.|...:...........:||||.:.:..
plant   221 W-----SLPNRPVYLWTLPMFHANGWSYTW-ATAAVGARNICVTRVDVPTIFNLIDKYQVTHMCA 279

  Fly   342 VPPIALFMINHPKLTQETAPHLKVVMSGAAPIGQHDVERFLNKFPNTVFKQ----------GYGM 396
            .|.:...:.|||......:| :||:.:||.|             |.||..:          ||||
plant   280 APMVLNMLTNHPAQKPLQSP-VKVMTAGAPP-------------PATVISKAEALGFDVSHGYGM 330

  Fly   397 TEASPVVL---LTPEGNK------------------VYASTGVLPASTEAKIVPLDGSDAKGVGP 440
            ||...:|:   |.||.::                  |:|...|..        |:.|...|..|
plant   331 TETGGLVVSCALKPEWDRLEPDERAKQKSRQGIRTAVFAEVDVRD--------PISGKSVKHDG- 386

  Fly   441 RTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIKVKGFQV 505
            .|.||:..||..||.||..:.|....:.....|..:||:.....||...:.||.|:::...|..:
plant   387 ATVGEIVFRGGSVMLGYYKDPEGTAASMREDGWFYTGDIGVMHPDGYLEVKDRSKDVVICGGENI 451

  Fly   506 PPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGEKASAE-EISAYVAERVAHYKKLE 569
            ...||||||..:|.|.||||...|.:..||.|.|.|.|:..:.:..| ||..:...::..| .:.
plant   452 SSTELEAVLYTNPAIKEAAVVAKPDKMWGETPCAFVSLKYHDGSVTEREIREFCKTKLPKY-MVP 515

  Fly   570 GGVIFVDEVPKNPTGKILRRELKE 593
            ..|:|::|:||..||||.:..|::
plant   516 RNVVFLEELPKTSTGKIQKFLLRQ 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	137/544 (25%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	135/536 (25%)
AAE2	NP_177848.1	ttLC_FACS_AEE21_like	13..538	CDD:341283	136/541 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810