DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pdgy and 4CL3

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_176686.1	Gene:	4CL3 / 842814	AraportID:	AT1G65060	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	581	Identity:	206/581 - (35%)
Similarity:	301/581 - (51%)	Gaps:	45/581 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 TASAQRERTQSVSET----DKFLHYSPEDGYYKTSPFDPVTIPN-VPLHEYVWRDFKKWERRTAA 94
            ||:....:....::|    |..|.:||.......|....:.||| :|||.|.   |:|....:..
plant     3 TAALHEPQIHKPTDTSVVSDDVLPHSPPTPRIFRSKLPDIDIPNHLPLHTYC---FEKLSSVSDK 64

  Fly    95 VCVI---TDRQYTFAQ-----MRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEA 151
            .|:|   |.:.||:.:     .|.||..:      |..::|.||:.|.|.|..|:..:.:||...
plant    65 PCLIVGSTGKSYTYGETHLICRRVASGLY------KLGIRKGDVIMILLQNSAEFVFSFMGASMI 123

  Fly   152 GLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLSQ-ASKLVGRQIPIAVVRTSAEEALPE 215
            |...||.||.||..|:.:||..||||.::       |.|| ..||......:.::.|  :|..||
plant   124 GAVSTTANPFYTSQELYKQLKSSGAKLII-------THSQYVDKLKNLGENLTLITT--DEPTPE 179

  Fly   216 GAIDFSELTSTQNVRYEDLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNN-ITSNCEQVQASL 279
            ..:.||.|.:....  ...:...:...||...||||||||||||||:|:|.: |||..:||....
plant   180 NCLPFSTLITDDET--NPFQETVDIGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDN 242

  Fly   280 PLDLMGPQNTLPGVLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPP 344
            |...:...:.:..|||.||||.|..|:|:.|..|..:..|..|:....:..:.:::.:|..||||
plant   243 PNLYLKSNDVILCVLPLFHIYSLNSVLLNSLRSGATVLLMHKFEIGALLDLIQRHRVTIAALVPP 307

  Fly   345 IALFMINHPKLTQETAPHLKVVMSGAAPIGQHDVERFLNKFPNTVFKQGYGMTEASPVVLLT--- 406
            :.:.:..:|.:.......::.|:|||||:|:...:....:.|..:..||||||||.||:.::
plant   308 LVIALAKNPTVNSYDLSSVRFVLSGAAPLGKELQDSLRRRLPQAILGQGYGMTEAGPVLSMSLGF 372

  Fly   407 ---PEGNKVYASTGVLPASTEAKIVPLDGSDAKGVGPRTTGELCVRGPQVMAGYLNNDEANQVTF 468
               |...| ..|.|.:..:.|.|:|.|:  ....:|....||:|:||.|:|..|||:.||...|.
plant   373 AKEPIPTK-SGSCGTVVRNAELKVVHLE--TRLSLGYNQPGEICIRGQQIMKEYLNDPEATSATI 434

  Fly   469 YPGNWLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFN 533
            ....||.:||:.:.|||...:|.||:||:||.|||||||||||::|.:|..|.:|||.....|..
plant   435 DEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELESLLINHHSIADAAVVPQNDEVA 499

  Fly   534 GEAPRAIVVLRQGEKASAEEISAYVAERVAHYKKLEGGVIFVDEVPKNPTGKILRRELKEK 594
            ||.|.|.||...|...:.|::..|||::|..||:|. .|.||..:||:|:|||||::||.|
plant   500 GEVPVAFVVRSNGNDITEEDVKEYVAKQVVFYKRLH-KVFFVASIPKSPSGKILRKDLKAK 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	194/534 (36%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	181/500 (36%)
4CL3	NP_176686.1	PLN02246	26..561	CDD:215137	201/558 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54045
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	1	1.000	-	-		FOG0000951
OrthoInspector	1	1.000	-	-		otm2758
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.790