DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdgy and 4CL1

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_175579.1	Gene:	4CL1 / 841593	AraportID:	AT1G51680	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	568	Identity:	199/568 - (35%)
Similarity:	307/568 - (54%)	Gaps:	28/568 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 QSVSET-DKFLHYSPEDGYYKTSPFDPVTIPN-VPLHEYVWRDFKKWERRTAAVCVITDRQYTFA 106
            |:||:. :|..:.:..|..:: |....:.||| :.||:|::::..::..:...:...|...||::
plant     6 QAVSQVMEKQSNNNNSDVIFR-SKLPDIYIPNHLSLHDYIFQNISEFATKPCLINGPTGHVYTYS 69

  Fly   107 QMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQL 171
            .:...|...|.... |..:.:.||:.:.|||.||:.::.|.|...|.|.|..||.:||.|||:|.
plant    70 DVHVISRQIAANFH-KLGVNQNDVVMLLLPNCPEFVLSFLAASFRGATATAANPFFTPAEIAKQA 133

  Fly   172 TFSGAKFLVGTVSGFATLSQASKLVGRQ----IPIAVVRTSAEEALPEGAIDFSELTSTQNVRYE 232
            ..|..|.::      .......|:...|    :.|..:..:....:|||.:.|:|||.:.....|
plant   134 KASNTKLII------TEARYVDKIKPLQNDDGVVIVCIDDNESVPIPEGCLRFTELTQSTTEASE 192

  Fly   233 DLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNN-ITSNCEQVQASLPLDLMGPQNTLPGVLPF 296
            .:.: .|.|.||:|.||:|||||||||||||:|.. :||..:||....|.......:.:..|||.
plant   193 VIDS-VEISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPM 256

  Fly   297 FHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETAP 361
            ||||.|..:||..|..|..:..||.|:.:..:..:.:.:.::..:||||.|.:....:..:....
plant   257 FHIYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPMVPPIVLAIAKSSETEKYDLS 321

  Fly   362 HLKVVMSGAAPIGQHDVERFLN-KFPNTVFKQGYGMTEASPVVLLT------PEGNKVYASTGVL 419
            .::||.|||||:|: ::|..:| ||||....||||||||.||:.::      |...| ..:.|.:
plant   322 SIRVVKSGAAPLGK-ELEDAVNAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVK-SGACGTV 384

  Fly   420 PASTEAKIVPLDGSDAKGVGPRTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDE 484
            ..:.|.|||..|..|:  :.....||:|:||.|:|.|||||..|...|.....||.:||:...|:
plant   385 VRNAEMKIVDPDTGDS--LSRNQPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDD 447

  Fly   485 DGLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGEKA 549
            |...:|.||:|||||.|||||.||||||:|..||.|.:.||..:..|..||.|.|.||..:..:.
plant   448 DDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSEL 512

  Fly   550 SAEEISAYVAERVAHYKKLEGGVIFVDEVPKNPTGKILRRELKEKFSD 597
            |.:::..:|:::|..||:: ..|.|.:.:||.|:|||||::|:.|.::
plant   513 SEDDVKQFVSKQVVFYKRI-NKVFFTESIPKAPSGKILRKDLRAKLAN 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	189/529 (36%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	182/499 (36%)
4CL1	NP_175579.1	PLN02246	16..560	CDD:215137	195/558 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	70	1.000	Domainoid score	I3393
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80284
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54045
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	1	1.000	-	-		FOG0000951
OrthoInspector	1	1.000	-	-		otm2758
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.790