DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pdgy and AAE14

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001322322.1	Gene:	AAE14 / 839932	AraportID:	AT1G30520	Length:	560	Species:	Arabidopsis thaliana

Alignment Length:	560	Identity:	134/560 - (23%)
Similarity:	228/560 - (40%)	Gaps:	86/560 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 RRTAAVCVITDRQYTFAQMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEY-----PIATLGAI 149
            :|.|.|.|..:|:.|..:..|...:.|..| .:..|:..||::|...|...:     .:|.:|.:
plant    20 KRNAVVTVYGNRKRTGREFVDGVLSLAAGL-IRLGLRNGDVVSIAAFNSDLFLEWLLAVALVGGV 83

  Fly   150 -----------EAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLSQASKLVGRQIPIA 203
                       ||.:.:..|.||.                   .|:....:|....:....||..
plant    84 VAPLNYRWSLKEAKMAMLLVEPVL-------------------LVTDETCVSWCIDVQNGDIPSL 129

  Fly   204 VVRTSAEEALPEGAIDFSELTSTQNVRYEDLKAPKEA----SADDMVFLPFSSGTTGLPKGVMLS 264
            ..|...|....:.|.:.::..:|:.::...| .|..|    ::||.|.:.|:|||||.||||.:|
plant   130 KWRVLMESTSTDFANELNQFLTTEMLKQRTL-VPSLATYAWASDDAVVICFTSGTTGRPKGVTIS 193

  Fly   265 HNNITSNCEQVQASLPLDLMGPQNTLPGVLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMR 329
            |   .:...|..|.:.:...|..:......|..||.||:..|...:...|.: .:|.|.....::
plant   194 H---LAFITQSLAKIAIAGYGEDDVYLHTSPLVHIGGLSSAMAMLMVGACHV-LLPKFDAKTALQ 254

  Fly   330 SLDKYQGSILNLVPPIALFMINHPKLTQETAPH--LKVVMSGAAPIGQHDVERFLNKFPNTVFKQ 392
            .:::...:....||.:...:|...:.|:..|.:  ::.:::|...:....::..:|.||......
plant   255 VMEQNHITCFITVPAMMADLIRVNRTTKNGAENRGVRKILNGGGSLSSELLKEAVNIFPCARILS 319

  Fly   393 GYGMTEA-SPVVLLT-------------PEGNKVYASTGV-LPASTEAKIVPLDGSDAKGVGPRT 442
            .|||||| |.:..:|             |..|:....|.| .||.....:|.||...::
plant   320 AYGMTEACSSLTFMTLHDPTQESFKVTYPLLNQPKQGTCVGKPAPHIELMVKLDEDSSR------ 378

  Fly   443 TGELCVRGPQVMAGYLNNDEAN---QVTFYPGN--WLRSGDVAFYDEDGLFYITDRMKELIKVKG 502
            .|::..|||..|..|..:..|.   :.:....|  ||.:||:..:||.|..::..|....||..|
plant   379 VGKILTRGPHTMLRYWGHQVAQENVETSESRSNEAWLDTGDIGAFDEFGNLWLIGRSNGRIKTGG 443

  Fly   503 FQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVL-----------RQGE-KASAEEIS 555
            ..|.|.|:||||.:||.|:.|.|.|:.....||...|.|.|           |:|. :.|:|.:.
plant   444 ENVYPEEVEAVLVEHPGIVSAVVIGVIDTRLGEMVVACVRLQEKWIWSDVENRKGSFQLSSETLK 508

  Fly   556 AYV-AERVAHYKKLEGGVIFVDEVPKNPTGKILRRELKEK 594
            .:. .:.:..:|..:..|.:..:.|...|||:.|.|::.:
plant   509 HHCRTQNLTGFKIPKRFVRWEKQFPLTTTGKVKRDEVRRQ 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	134/560 (24%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	128/542 (24%)
AAE14	NP_001322322.1	PLN02860	1..560	CDD:215464	134/560 (24%)
		AFD_class_I	42..>269	CDD:302604	53/251 (21%)
		AFD_class_I	172..546	CDD:302604	102/383 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810