DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pdgy and AAE1

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_564116.1	Gene:	AAE1 / 838644	AraportID:	AT1G20560	Length:	556	Species:	Arabidopsis thaliana

Alignment Length:	590	Identity:	161/590 - (27%)
Similarity:	246/590 - (41%)	Gaps:	132/590 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 VPLHEYVWRDFKKWERRTAAVCVITDR--------QYTFAQMRDASAAFAVRLQTKFNLQKPDVL 131
            |||....:.|      |:|.  |..||        :||:.|.||.....|..| ::..:...||:
plant    14 VPLTPISFLD------RSAV--VYADRVSIVYGSVKYTWRQTRDRCVRIASAL-SQLGISTGDVV 69

  Fly   132 AICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLSQASKLV 196
            ::..||:|.......|...||..:.|:|..:....:|..|..||.|.:............|.:::
plant    70 SVLAPNVPAMVELHFGVPMAGALLCTLNIRHDSSLVAVLLRHSGTKVIFADHQFLQIAEGACEIL 134

  Fly   197 ---GRQIPIAVVRTSAEEALPEGAIDFSELT--------STQNVRYEDLKAPKEASAD------- 243
               |.::||.|:       :||      .||        |.:.:.|||:.|..::..:
plant   135 SNKGDKVPILVL-------IPE------PLTQSVSRKKRSEEMMEYEDVVAMGKSDFEVIRPTDE 186

  Fly   244 -DMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTLPGVL---PFFH------ 298
             |.:.:.::||||..||||:.||.....|      ||...|:...::.|..|   |.||
plant   187 CDAISVNYTSGTTSSPKGVVYSHRGAYLN------SLAAVLLNEMHSSPTYLWTNPMFHCNGWCL 245

  Fly   299 IYGLTVVMLSKLGQGCRLATMPCFK---PDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETA 360
            ::|:|.:.          .|..|.:   ......::.:::.:.:...|.|...:||.|:..|:..
plant   246 LWGVTAIG----------GTNICLRNVTAKAIFDNISQHKVTHMGGAPTILNMIINAPESEQKPL 300

  Fly   361 PHLKVVMSGAAPIGQHDVERFLNKFPNTVFK---------QGYGMTEA-SPVVLLT--PEGNKVY 413
            |.....::||||...|           .:||         ..||:||. .|..:.|  ||.:.
plant   301 PGKVSFITGAAPPPAH-----------VIFKMEELGFSMFHSYGLTETYGPGTICTWKPEWDS-- 352

  Fly   414 ASTGVLPASTEAKIVPLDGSD-------------------AKGVGPRTTGELCVRGPQVMAGYLN 459
                 ||...:||:....|.:                   |.||   |.||:..||..||.|||.
plant   353 -----LPREEQAKMKARQGVNHLGLEEIQVKDPVTMRTLPADGV---TMGEVVFRGNTVMNGYLK 409

  Fly   460 NDEANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAA 524
            |.||.:..| .|.|..|||:.....||...:.||.|::|...|..:...|:|:.|..||.:||||
plant   410 NPEATKEAF-KGGWFWSGDLGVKHPDGYIELKDRSKDIIISGGENISSIEVESTLFTHPCVLEAA 473

  Fly   525 VFGIPHEFNGEAPRAIVVLRQGEKASAEEISAYVAERVAHYKKLEGGVIFVDEVPKNPTGKILRR 589
            |...|.|:.||...|.|.|:.|.||||||:.:|..:|:.|| .....::| :::||..|||:.:.
plant   474 VVARPDEYWGETACAFVKLKDGSKASAEELISYCRDRLPHY-MAPRSIVF-EDLPKTSTGKVQKF 536

  Fly   590 ELKEK 594
            .|:.|
plant   537 VLRTK 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	159/588 (27%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	152/557 (27%)
AAE1	NP_564116.1	PRK08162	4..545	CDD:236169	161/590 (27%)
AAE1	NP_564116.1	ttLC_FACS_AEE21_like	13..540	CDD:213326	160/587 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810