DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pdgy and OPCL1

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_564115.1	Gene:	OPCL1 / 838639	AraportID:	AT1G20510	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	538	Identity:	186/538 - (34%)
Similarity:	282/538 - (52%)	Gaps:	26/538 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 YYKTSPFDPVTIPNVPLHEYVWRDFKKWERRTAAVCVITDRQYTFAQMRDASAAFAVRLQTKFNL 125
            |.|.:|. |:. ||..|....:...:....|.|.:...|.:..||.::..|..:.|..| ::..:
plant    18 YSKRTPI-PLP-PNPSLDVTTFISSQAHRGRIAFIDASTGQNLTFTELWRAVESVADCL-SEIGI 79

  Fly   126 QKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLS 190
            :|..|:.:..||...:|:..|..:..|..:||.||:.|.:|||:|:..|.......|......:|
plant    80 RKGHVVLLLSPNSILFPVVCLSVMSLGAIITTTNPLNTSNEIAKQIKDSNPVLAFTTSQLLPKIS 144

  Fly   191 QASKLVGRQIPIAVVRTSAEEALPEGAIDFSELTSTQNVRYEDLKAPKEASADDMVFLPFSSGTT 255
            .|:|    ::||.::    :|...:...|...|...........:..:....||...|.:|||||
plant   145 AAAK----KLPIVLM----DEERVDSVGDVRRLVEMMKKEPSGNRVKERVDQDDTATLLYSSGTT 201

  Fly   256 GLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTLPGVLPFFHIYGLTVVMLSKLGQGCRLATMP 320
            |:.|||:.||.|:.:..:.:......| .|.|..:..| |.||||||.......|..|..:..:.
plant   202 GMSKGVISSHRNLIAMVQTIVNRFGSD-DGEQRFICTV-PMFHIYGLAAFATGLLAYGSTIIVLS 264

  Fly   321 CFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETAPH----LKVVMSGAAPIGQHDVERF 381
            .|:..:.|.::.|||.:.|.|||||.:.|:|  ...|..|.:    :..|:.|.||:.:...|.|
plant   265 KFEMHEMMSAIGKYQATSLPLVPPILVAMVN--GADQIKAKYDLSSMHTVLCGGAPLSKEVTEGF 327

  Fly   382 LNKFPNTVFKQGYGMTEASPVVLLTP--EGNKVYASTGVLPASTEAKIV-PLDGSDAKGVGPRTT 443
            ..|:|.....||||:||::.:...|.  |.::.|.:.|.|.||.|.:|| |:.|   :.:||:.|
plant   328 AEKYPTVKILQGYGLTESTGIGASTDTVEESRRYGTAGKLSASMEGRIVDPVTG---QILGPKQT 389

  Fly   444 GELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPA 508
            |||.::||.:|.||.:|:||...|.....|||:||:.:.||||..::.||:|||||.||:||.||
plant   390 GELWLKGPSIMKGYFSNEEATSSTLDSEGWLRTGDLCYIDEDGFIFVVDRLKELIKYKGYQVAPA 454

  Fly   509 ELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGEKASAEEISAYVAERVAHYKKLEGGVI 573
            ||||:|..||:|.:|||...|.:..|:.|.|.||.:.|...|.:.|..:||::||.||::. .|.
plant   455 ELEALLLTHPEITDAAVIPFPDKEVGQFPMAYVVRKTGSSLSEKTIMEFVAKQVAPYKRIR-KVA 518

  Fly   574 FVDEVPKNPTGKILRREL 591
            ||..:||||:|||||::|
plant   519 FVSSIPKNPSGKILRKDL 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	180/522 (34%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	173/494 (35%)
OPCL1	NP_564115.1	4CL	26..536	CDD:341230	181/527 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54045
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2758
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.790