DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdgy and 4CL8

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_198628.2	Gene:	4CL8 / 833792	AraportID:	AT5G38120	Length:	550	Species:	Arabidopsis thaliana

Alignment Length:	566	Identity:	176/566 - (31%)
Similarity:	285/566 - (50%)	Gaps:	37/566 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 AQRERTQSVSETDKFLHYSPEDGYYKT-----SPFDPVTIP---NVPLHEYVWRDFKKWERRTAA 94
            |..:|:.|:.:        |.:|:..:     |...|:.:|   ::.:..::  ..:.:..:||.
plant     2 ANSQRSSSLID--------PRNGFCTSNSTFYSKRKPLALPSKESLDITTFI--SSQTYRGKTAF 56

  Fly    95 VCVITDRQYTFAQMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVN 159
            :...||.:.:|:.:..|....|..|.....:::.||:.:..||....||..|..:..|..:||.|
plant    57 IDAATDHRISFSDLWMAVDRVADCLLHDVGIRRGDVVLVLSPNTISIPIVCLSVMSLGAVLTTAN 121

  Fly   160 PVYTPDEIARQLTFSGAKFLVGTVSGFATLSQASKLVGRQIPIAVVRTSAEEALPEGAIDFSELT 224
            |:.|..||.||:..|..|.      .|.|...|.|:....|.|.:.|......:|.|......||
plant   122 PLNTASEILRQIADSNPKL------AFTTPELAPKIASSGISIVLERVEDTLRVPRGLKVVGNLT 180

  Fly   225 STQNVRYEDLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNT 289
            ..............:...||...|.:||||||..|||..||.|:.::..:..|. |.:  .||.|
plant   181 EMMKKEPSGQAVRNQVHKDDTAMLLYSSGTTGRSKGVNSSHGNLIAHVARYIAE-PFE--QPQQT 242

  Fly   290 LPGVLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPK 354
            ....:|.||.:||...:|:.|..|..:..:|.|...:.|.:::||:.:.|.||||:.:.|||...
plant   243 FICTVPLFHTFGLLNFVLATLALGTTVVILPRFDLGEMMAAVEKYRATTLILVPPVLVTMINKAD 307

  Fly   355 --LTQETAPHLKVVMSGAAPIGQHDVERFLNKFPNTVFKQGYGMTEA--SPVVLLTPEGNKVYAS 415
              :.:.....|:.|..|.||:.:...:.|:.|:|.....|||.:||:  :...:.:.|.::.|.:
plant   308 QIMKKYDVSFLRTVRCGGAPLSKEVTQGFMKKYPTVDVYQGYALTESNGAGASIESVEESRRYGA 372

  Fly   416 TGVLPASTEAKIVPLDGSDAKGVGPRTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVA 480
            .|:|....||:||  |.:..:.:|...||||.::||.:..||..|:|  ::....| ||::||:.
plant   373 VGLLSCGVEARIV--DPNTGQVMGLNQTGELWLKGPSIAKGYFRNEE--EIITSEG-WLKTGDLC 432

  Fly   481 FYDEDGLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQ 545
            :.|.||..:|.||:|||||.||:|||||||||:|.:||.||:|||...|.:..|:.|.|.|..:.
plant   433 YIDNDGFLFIVDRLKELIKYKGYQVPPAELEALLLNHPDILDAAVIPFPDKEAGQFPMAYVARKP 497

  Fly   546 GEKASAEEISAYVAERVAHYKKLEGGVIFVDEVPKNPTGKILRREL 591
            ......:::..:::::||.|||:. .|.|:|.:||.|:||.||::|
plant   498 ESNLCEKKVIDFISKQVAPYKKIR-KVAFIDSIPKTPSGKTLRKDL 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	168/519 (32%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	163/491 (33%)
4CL8	NP_198628.2	PLN02574	17..542	CDD:215312	170/541 (31%)
4CL8	NP_198628.2	4CL	33..542	CDD:213272	168/525 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54045
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2758
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.790