DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pdgy and 4CL5

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_188760.3	Gene:	4CL5 / 821677	AraportID:	AT3G21230	Length:	570	Species:	Arabidopsis thaliana

Alignment Length:	573	Identity:	190/573 - (33%)
Similarity:	303/573 - (52%)	Gaps:	41/573 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 TQSVSETDKFLHYSPEDGYYKTSPFDPVTIPN-VPLHEYVWRDFK-KWERRTAAVCVI---TDRQ 102
            |:.:.:.|:  ...|...:...|....:.||| :||.:||::.|. ..:..::..|:|   |.|.
plant    11 TKKIDQEDE--EEEPSHDFIFRSKLPDIFIPNHLPLTDYVFQRFSGDGDGDSSTTCIIDGATGRI 73

  Fly   103 YTFAQMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEI 167
            .|:|.::......|..:. :..::..||:.:.|||.||:.::.|.....|...||.||.||..||
plant    74 LTYADVQTNMRRIAAGIH-RLGIRHGDVVMLLLPNSPEFALSFLAVAYLGAVSTTANPFYTQPEI 137

  Fly   168 ARQLTFSGAKFLVGTVSGFATLSQASKLVGRQIPIAVVRTSAEEAL----PEGAIDFSELTSTQN 228
            |:|...|.||.:   ::....:.:.:.|....:.|..:....:..:    .:|.:.|:|||....
plant   138 AKQAKASAAKMI---ITKKCLVDKLTNLKNDGVLIVCLDDDGDNGVVSSSDDGCVSFTELTQADE 199

  Fly   229 VRYEDLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNN-ITSNCEQVQASLPLDLMGPQNTLPG 292
            .   :|..|| .|.:|.|.:|:||||||||||||::|.. :||..::|....|.......:.:..
plant   200 T---ELLKPK-ISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLNFTANDVILC 260

  Fly   293 VLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQ 357
            .||.||||.|..:|||.:..|..|..:|.|:.:..|..:.:|:.:::.:.||:.|..|..|:..:
plant   261 FLPMFHIYALDALMLSAMRTGAALLIVPRFELNLVMELIQRYKVTVVPVAPPVVLAFIKSPETER 325

  Fly   358 ETAPHLKVVMSGAAPIGQHDVERFLNKFPNTVFKQGYGMTEASPVV---------LLTPEGNKVY 413
            .....:::::||||.:.:...:....||||.:|.|||||||:..|.         ..|..|
plant   326 YDLSSVRIMLSGAATLKKELEDAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFKTKSG---- 386

  Fly   414 ASTGVLPASTEAKIVPLDGSDAKGVG-PRT-TGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRS 476
             :.|.:..:.|.|:|..:    .|:. ||. :||:||||.|:|.||||:.||...|.....||.:
plant   387 -ACGTVIRNAEMKVVDTE----TGISLPRNKSGEICVRGHQLMKGYLNDPEATARTIDKDGWLHT 446

  Fly   477 GDVAFYDEDGLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIV 541
            ||:.|.|:|...:|.||:|||||.||:||.||||||:|..||.|.:|||..:..|...|.|.|.|
plant   447 GDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPSIDDAAVVAMKDEVADEVPVAFV 511

  Fly   542 VLRQGEKASAEEISAYVAERVAHYKKLEGGVIFVDEVPKNPTGKILRRELKEK 594
            ...||.:.:.:::.:||.::|.|||::: .|.|::.:||..:|||||::|:.|
plant   512 ARSQGSQLTEDDVKSYVNKQVVHYKRIK-MVFFIEVIPKAVSGKILRKDLRAK 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	182/538 (34%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	171/503 (34%)
4CL5	NP_188760.3	PLN02246	20..567	CDD:215137	188/562 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	70	1.000	Domainoid score	I3393
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H80284
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54045
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	1	1.000	-	-		FOG0000951
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.790