DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pdgy and AAE7

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_188316.1	Gene:	AAE7 / 820946	AraportID:	AT3G16910	Length:	569	Species:	Arabidopsis thaliana

Alignment Length:	604	Identity:	162/604 - (26%)
Similarity:	243/604 - (40%)	Gaps:	143/604 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 WRDFKK--------------WERRTAAVCVIT-------DRQYTFAQMRDASAAFAVRLQTKFNL 125
            |||...              |....|||...|       .|:||:.|..|.....|..|..: ::
plant     6 WRDIDDLPKIPANYTALTPLWFLDRAAVVHPTRKSVIHGSREYTWRQTYDRCRRLASALADR-SI 69

  Fly   126 QKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLS 190
            .....:||..||:|....|..|....|..:..||.......:|..|:.|.:..::.....|....
plant    70 GPGSTVAIIAPNIPAMYEAHFGVPMCGAVLNCVNIRLNAPTVAFLLSHSQSSVIMVDQEFFTLAE 134

  Fly   191 QASKLVGRQI------PIAVV---RTSAEE----ALPEGAIDFSELTSTQNVRYEDLKAPKEASA 242
            .:.:|:..:.      |:.:|   .|.|.|    ||.:|||::.:..:|.:..|     |.:..|
plant   135 DSLRLMEEKAGSSFKRPLLIVIGDHTCAPESLNRALSKGAIEYEDFLATGDPNY-----PWQPPA 194

  Fly   243 DD--MVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQA-SLPLDLMGPQN--TLPGVLPFFHIYG- 301
            |:  .:.|.::||||..||||:|.|..     ..:.| |.|| :.|.|:  .....||.||..|
plant   195 DEWQSIALGYTSGTTASPKGVVLHHRG-----AYIMALSNPL-IWGMQDGAVYLWTLPMFHCNGW 253

  Fly   302 ---LTVVMLSKLGQGCRLATMPCFK---PDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQET- 359
               .::.:||        .|..|.:   ..:....:.||:.:.....|.:...::|.||  ::|
plant   254 CFPWSLAVLS--------GTSICLRQVTAKEVYSMIAKYKVTHFCAAPVVLNAIVNAPK--EDTI 308

  Fly   360 --APH-LKVVMSGAAPIGQHDVERFLNKFPNTVFKQG---------YGMTEA---SPVVLLTPEG 409
              .|| :.|:.:||||.            |:.:|...         ||::|.   |.|....||.
plant   309 LPLPHTVHVMTAGAAPP------------PSVLFSMNQKGFRVAHTYGLSETYGPSTVCAWKPEW 361

  Fly   410 NKVYASTGVLPASTEAKI------------------------VPLDGSDAKGVGPRTTGELCVRG 450
            :.       ||..|:||:                        ||.||        :|.||:..||
plant   362 DS-------LPPETQAKLNARQGVRYTGMEQLDVIDTQTGKPVPADG--------KTAGEIVFRG 411

  Fly   451 PQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPAELEAVLR 515
            ..||.|||.|.|||:.|| .|.|..|||:|....|....|.||.|::|...|..:...|:|.|:.
plant   412 NMVMKGYLKNPEANKETF-AGGWFHSGDIAVKHPDNYIEIKDRSKDVIISGGENISSVEVENVVY 475

  Fly   516 DHPKILEAAVFGIPHEFNGEAPRAIVVL-----RQGEKASAEEISAYVAERVAHYKKLEGGVIFV 575
            .||.:|||:|...|.|...|:|.|.|.|     :..:...|::|..:..|::..| .:...|:|
plant   476 HHPAVLEASVVARPDERWQESPCAFVTLKSDYEKHDQNKLAQDIMKFCREKLPAY-WVPKSVVF- 538

  Fly   576 DEVPKNPTGKILRRELKEK 594
            ..:||..||||.:..|:.|
plant   539 GPLPKTATGKIQKHILRTK 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	162/604 (27%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	152/564 (27%)
AAE7	NP_188316.1	PLN02479	3..569	CDD:178097	162/604 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810