Protein Alignment pdgy and Acsl3

DIOPT Version :10

• Sequence 1: NP_572988.1
• Gene: pdgy / 32426
• FlyBaseID: FBgn0027601
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001396004.1
• Gene: Acsl3 / 74205
• MGIID: 1921455
• Length: 746
• Species: Mus musculus
• Alignment Length: 617
• Identity: 138/617 - (22%)
• Similarity: 235/617 - (38%)
• Gaps: 184/617 - (29%)

  Fly   126 QKPDV-LAICLPNLPEYPI----------------ATLG--AIEAGLTVTTVNPVYTPDEIARQL 171
            |||.. :||......|:.|                ||||  ||..||..|.|..:.|..|:.:
Mouse   156 QKPKANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQ-- 218

  Fly   172 TFSGAKFLVGTVSGFATLSQASKLVGRQIPIAVV--RTSAEEALPEGAIDFSELTSTQ------N 228
                           ..|.....||.|...|..|  :.......|:|.| ...:.:.|      |
Mouse   219 ---------------TKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGVI-VHTMAAVQALGVKAN 267

  Fly   229 VRYEDLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLP------------- 280
            |   :.||..:....|:..:.::||:||:|||||:||:||.::...:...:|
Mouse   268 V---EKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMARRIPRLGQITGHEPAAA 329

  Fly   281 LDL-----------MGPQNTLPGVLPFFHIYGLTVVMLSKLGQGCRLA----------------- 317
            ::|           :..::...|.||..|:..|:..::. |..|||:.
Mouse   330 VELWRNRKVHQPASLREEDVYIGYLPLAHVLELSAELVC-LSHGCRIGYSSPQTLADQSSKIKKG 393

  Fly   318 ----------TMPCFKPDDFMRSLDKYQGSILNLVPPIALFMIN------HPKLTQET------- 359
                      |:....|:    .:|:...:::|.|..::.|..|      :.|:.|.:
Mouse   394 SKGDTSVLKPTLMAAVPE----IMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPL 454

  Fly   360 -------------APHLKVVMSGAAPIGQHDVERFLNKFPNTVFKQGYGMTEASPVVLLTPEGNK 411
                         ..::::::.|.||:.. ..:||:|........||||:||::....:|    :
Mouse   455 CDRFVFRNVRRLLGGNIRLLLCGGAPLSA-TTQRFMNICFCCPVGQGYGLTESTGAGTIT----E 514

  Fly   412 VY-ASTGVLPASTEAKIVPLDGSDAKGV----GPRTTGELCVRGPQVMAGYLNNDEANQVTFYPG 471
            |: .:||.:.|......:.|...:..|.    .|...||:.:.|..|..||..|:...:..|:..
Mouse   515 VWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFED 579

  Fly   472 ----NWLRSGDVAFYDEDGLFYITDRMKELIKVK-GFQVPPAELEAVLRDHPKI---------LE 522
                .||.:||:..:|.||...|.||.|:|:|:: |..|...::||.|::.|.|         ..
Mouse   580 ENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYH 644

  Fly   523 AAVFG--IPHEFNGEAPRAIVVL--RQGEKASAEEI--SAYVAERV----------AHYKKLEGG 571
            :.|.|  :|::      :.:..|  .:|.|.:.||:  |:.:...|          |..:|.|..
Mouse   645 SYVIGFVVPNQ------KELTELARTKGFKGTWEELCNSSEMENEVLKVLSEAAISASLEKFEIP 703

  Fly   572 V-IFVDEVPKNP-TG------KILRRELKEKF 595
            : |.:...|..| ||      |:.|:|||..:
Mouse   704 LKIRLSPDPWTPETGLVTDAFKLKRKELKTHY 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_572988.1	Firefly_Luc_like	93..587	CDD:341237	134/607 (22%)
Acsl3	NP_001396004.1	LC_FACS_euk1	130..731	CDD:341294	135/611 (22%)
		entF	<229..>305	CDD:236668	24/79 (30%)